Results 251 to 260 of about 88,078 (299)
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Adaptation by Hyperpolarization
Science, 1997Adaption to external stimuli prevents us from being overwhelmed by the constant bombardment of our senses: A noxious odor, immediately repulsive, becomes hardly noticeable; after a time, the sound of traffic is no longer annoying. A report in this week's issue by Carandini and Ferster (p.
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Current Pharmaceutical Biotechnology, 2010
Hyperpolarized (HP) (13)C labeled compounds can be used as MR contrast agents to investigate metabolic pathways in vivo in almost real time. To date, a high proportion of reported studies have utilized HP 1-(13)C pyruvate to investigate intracellular metabolism in tumors and other tissues. The long T(1) relaxation time of the carboxylate carbon enables
Ian J, Rowland +3 more
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Hyperpolarized (HP) (13)C labeled compounds can be used as MR contrast agents to investigate metabolic pathways in vivo in almost real time. To date, a high proportion of reported studies have utilized HP 1-(13)C pyruvate to investigate intracellular metabolism in tumors and other tissues. The long T(1) relaxation time of the carboxylate carbon enables
Ian J, Rowland +3 more
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Mobilization of Transmitter by Hyperpolarization
Nature, 1962RECENT investigations have shown that repetitive stimulation produces hyperpolarization of nerve terminals1,2. It has been suggested that such a hyperpolarization could account for post-activation potentiation, since the height of the action potential in the pre-synaptic terminals would be increased, and this in turn might enhance synaptic ...
J I, HUBBARD, W D, WILLIS
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Quantification in Hyperpolarized NMR
The Journal of Physical Chemistry Letters, 2016Quantitative aspects of hyperpolarized NMR are analyzed in the present work, and it is shown theoretically and experimentally that measured "apparent" signal enhancements could deviate significantly from real enhancements of polarization. Expressions are given as a function of spin count to deduce real enhancements from measured "apparent" enhancements,
Arnab, Dey, Narayanan, Chandrakumar
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Hyperpolarizing Water with Parahydrogen
ChemPhysChem, 2017AbstractStudies of water‐based systems are of fundamental interest for nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) as water is the most abundant and important medium for global living. Hence, increasing the polarization of water and dissolved compounds is particularly attractive for biomedical applications such as ...
Sören Lehmkuhl +6 more
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Hyperpolarized Molecules in Solution
2011Hyperpolarization is a technique to enhance the nuclear polarization and thereby increase the available signal in magnetic resonance (MR). This chapter provides an introduction to the concept of hyperpolarization as well as an overview of dynamic nuclear polarization (DNP) and para-hydrogen induced polarization (PHIP), two methods used to generate ...
Jan Henrik, Ardenkjaer-Larsen +3 more
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Coronary Artery Disease, 1991
This review addresses the recent emergence in the literature of a putative factor called endothelium-derived hyperpolarizing factor (EDHF). The EDHF is characterized by the fact that it is emitted from the endothelium and hyperpolarizes the arterial smooth muscles.
Beny, Jean-Louis +1 more
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This review addresses the recent emergence in the literature of a putative factor called endothelium-derived hyperpolarizing factor (EDHF). The EDHF is characterized by the fact that it is emitted from the endothelium and hyperpolarizes the arterial smooth muscles.
Beny, Jean-Louis +1 more
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ENDOTHELIUM‐DERIVED HYPERPOLARIZING FACTOR
Clinical and Experimental Pharmacology and Physiology, 1996SUMMARY1. Not all endothelium‐dependent relaxation can be full explained by the release of either nitric oxide (NO) and/or prostacyclin. Another unidentified substance(s) that hyperpolarizes the underlying vascular smooth muscle cells (endothelium‐derived hyperpolarizing factor; EDHF) contributes to endothelium‐dependent relaxations.2. In blood vessels
Vanhoutte, PMGR, Félétou, M
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Endothelium-Derived Hyperpolarizing Factor
Journal of Vascular Research, 1990Although nitric oxide appears to be the major endothelium-derived relaxing factor (EDRF), it cannot explain all endothelium-dependent responses of isolated arteries. Thus, acetylcholine causes an endothelium-dependent, transient hyperpolarization, which is due to the release from the endothelial cells of a diffusible substance (endothelium-derived ...
Komori, K, Vanhoutte, PMGR
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Hyperpolarized 83Kr MRI of lungs
Journal of Magnetic Resonance, 2008Hyperpolarized (hp) (83)Kr (spin I=9/2) is a promising gas-phase contrast agent that displays sensitivity to the surface chemistry, surface-to-volume ratio, and surface temperature of the surrounding environment. This proof-of-principle study demonstrates the feasibility of ex vivo hp (83)Kr magnetic resonance imaging (MRI) of lungs using natural ...
Zackary I, Cleveland +5 more
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