Results 11 to 20 of about 798,798 (261)

Delayed Drug Hypersensitivity Reactions: Molecular Recognition, Genetic Susceptibility, and Immune Mediators

open access: yesBiomedicines, 2023
Drug hypersensitivity reactions are classified into immediate and delayed types, according to the onset time. In contrast to the immediate type, delayed drug hypersensitivity mainly involves T lymphocyte recognition of the drug antigens and cell ...
Mu-Tzu Chu   +3 more
doaj   +1 more source

Immediate Hypersensitivity Reaction to Composite Restorations

open access: yesNigerian Dental Journal, 2020
Restorative materials used in dentistry are constantly exposed to salivary components like enzymes that have a high impact on the degradation of  these materials and subsequent leaching of some of their constituents which may be harmful to the oral ...
O.H. Oderinu, O.E. Makinde
doaj   +1 more source

Immediate hypersensitivity reaction followed by successful oral desensitization to ursodiol

open access: yesAllergy, Asthma & Clinical Immunology, 2021
Background Immediate hypersensitivity reaction to ursodiol is rare and there is no previously published protocol on ursodiol desensitization.
Erika Yue Lee, Christine Song
doaj   +1 more source

Current practice for diagnosing immediate drug hypersensitivity reactions in Korea [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2021
Background/Aims Skin (STs) and drug provocation (DPTs) tests are essential for identifying the culprit drugs causing drug hypersensitivity reactions (DHRs).
Sung-Yoon Kang   +3 more
doaj   +1 more source

Protein contact dermatitis - case report [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2013
Protein contact dermatitis is a skin condition not well known and underdiagnosed by dermatologists, resulting from an IgE-mediated allergic reaction. Clinically it presents as a chronic hand and/or forearms eczema of occupational origin, especially in ...
Ana Rita Rodrigues Barata   +1 more
doaj   +1 more source

Converter Phenotype: A New Profile That Is Not Exclusive to Taxanes

open access: yesFrontiers in Allergy, 2022
Introduction: Phenotype I hypersensitivity reactions are the most commonly reported drug reactions; however, precision medicine has made it possible to characterize new phenotypes. A recent communication proposed the existence of a “converter phenotype,”
Teodorikez Wilfox Jimenez-Rodriguez   +13 more
doaj   +1 more source

Campylobacter jejuni infection and IgE sensitization in up to 2-year-old infants [PDF]

open access: yesVojnosanitetski Pregled, 2015
Background/Aim. The “hygiene hypothesis” addresses the correlation between the occurrence of atopy and the frequency of infections in the earliest age, explaining an increase in the incidence of atopic diseases by living in good, infection-free,
Jovanović Dara   +7 more
doaj   +1 more source

Predominant patterns of β-lactam hypersensitivity in a single German Allergy Center: exanthem induced by aminopenicillins, anaphylaxis by cephalosporins

open access: yesAllergy, Asthma & Clinical Immunology, 2020
Background Penicillins and other β-lactam antibiotics are the most common elicitors of allergic drug reaction. However, data on the pattern of clinical reaction types elicited by specific β-lactams are scarce and inconsistent.
Philipp Schrüfer   +3 more
doaj   +1 more source

Management of type 1 immediate hypersensitivity reactions to antituberculosis drug: succesful desensitization

open access: yesAllergy, Asthma & Clinical Immunology, 2022
Objective In this study, it was aimed to investigate the prevalence of type 1 hypersensitivity reaction under tuberculosis treatment and the management of hypersensitivity. Methods The study is a case series.
Zeynep Yegin Katran   +3 more
doaj   +1 more source

MRGPRX2 and Immediate Drug Hypersensitivity: Insights from Cultured Human Mast Cells.

open access: yesJournal of investigational allergology & clinical immunology, 2020
BACKGROUND AND OBJECTIVE Mast cell (MC) degranulation via activation of the Mas-related G protein-coupled receptor X2 (MRGPRX2) is held to be of key importance for immediate drug hypersensitivity (IDH). However, data in humans are limited to observations
J. Elst   +13 more
semanticscholar   +1 more source

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