Results 41 to 50 of about 52,142 (265)

Hypersensitivity to Gadolinium-Based Contrast Media

open access: yesFrontiers in Allergy, 2022
Gadolinium-based contrast agents (GBCAs) are frequently used in magnetic resonance imaging (MRI) examinations to increase sensitivity in diagnoses. Recently, an increase in the description of hypersensitivity reactions to GBCAs has been detected.
M. Teresa Gracia Bara   +27 more
doaj   +1 more source

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

open access: yesAdvanced Science, EarlyView.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su   +7 more
wiley   +1 more source

The incidence of anaphylaxis in Emergency Room of Songklanagarind Hospital

open access: yesJournal of Health Science and Medical Research (JHSMR), 2010
Objective: To study the incidence rate of anaphylaxis in the emergency room of Songklanagarind Hospital. Material and Methods: The medical records of patients diagnosed as having anaphylaxis who visited Songklanagarind Hospital's Emergency Room from June
Darm Rungrotkumnerd   +2 more
doaj  

A Case of Immediate Hypersensitivity Reaction to Maltitol

open access: yesCase Reports in Medicine, 2017
Background. Maltitol is a sugar alcohol that is frequently used as a noncaloric sweetener, although it is also used as an excipient, a plasticizer in gelatin capsules, and an emollient.
Ana Rodríguez Trabado   +4 more
doaj   +1 more source

Biomarkers of immediate drug hypersensitivity

open access: yesAllergy, 2023
AbstractImmediate drug hypersensitivity reactions (IDHRs) are a burden for patients and the health systems. This problem increases when taking into account that only a small proportion of patients initially labelled as allergic are finally confirmed after an allergological workup.
Cristobalina Mayorga   +5 more
openaire   +5 more sources

O‐GlcNAcylation Regulation of SNAP29‐Dependent Autophagy Activation Dictates Chemoresistance in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Model illustrating the proposed mechanism by which chemotherapy‐induced downregulation of OGT disrupts SNAP29 O‐GlcNAcylation, promoting STX17‐SNAP29‐VAMP8 SNARE complex assembly and protective autophagy, leading to chemoresistance, which in turn establishes a feedforward loop to perpetuate drug tolerance.
Liang Tang   +9 more
wiley   +1 more source

The Time Delay Between Drug Intake and Bronchospasm for Nonsteroidal Antiinflammatory Drugs Sensitive Patients

open access: yesWorld Allergy Organization Journal, 2010
A study was performed to assess the time between drug intake and drug induced hypersensitivity reaction for patients sensitive to nonsteroidal antiinflammatory drugs (NSAID) in clinical patient history and after oral provocation tests.
Giedre Grigiene, MD   +2 more
doaj   +1 more source

Distinct Neuropsychiatric Profiles Associated With 17p11.2 Deletions and RAI1 Variants in Smith–Magenis Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Smith–Magenis syndrome (SMS) results from either a recurrent 17p11.2 deletion or pathogenic variants in the retinoic acid induced 1 gene (RAI1). While neurodevelopmental impairment and behavioral dysregulation are well recognized, systematic genotype‐stratified analyses across psychiatric domains remain limited.
Albin Blanc   +7 more
wiley   +1 more source

Specific questionnaire detects a high incidence of intra-operative hypersensitivity reactions

open access: yesClinics, 2018
OBJECTIVE: To assess the incidence of intra-operative immediate hypersensitivity reactions and anaphylaxis. METHODS: A cross-sectional observational study was conducted at the Department of Anesthesiology, University of São Paulo School of Medicine ...
Laila S. Garro   +8 more
doaj   +1 more source

Female‐Specific Risk of TAS2R Variants in Chronic Rhinosinusitis: A Hospital‐Based Cohort Study From the Taiwan Precision Medicine Initiative

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Bitter taste receptors (T2Rs) function in the innate immune defense of the sinonasal mucosa; however, the genetic association between the TAS2R gene family and chronic rhinosinusitis (CRS) remains understudied in Asian populations.
Rong‐San Jiang   +6 more
wiley   +1 more source

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