Results 61 to 70 of about 54,107 (304)

Hypersensitivity reactions to contrast media: Part 1. Management of immediate and non-immediate hypersensitivity reactions in adults. Updated guidelines by the ESUR Contrast Media Safety Committee [PDF]

Hypersensitivity reactions to iodine-based, gadolinium-based and ultrasound contrast agents are a heterogeneous group that occur infrequently and can be classified as either immediate or non-immediate.
van de Ven, Annick A. J. M., Clément, Olivier, Dekkers, Ilona A., Mallio, Carlo A., Stacul, Fulvio, Quattrocchi, Carlo C., van de Ven, Annick A.J.M.; id_orcid, Correas, Jean Michel, Romanini, Laura, Radbruch, Alexander, Vega, Francisco, van der Molen, Aart J., Bellin, Marie-France, Deike, Katerina, Bellin, Marie France, Sebastià, Carmen, Geenen, Remy W.F., Bertolotto, Michele, Correas, Jean-Michel, Roditi, Giles, Heinz, Gertraud, Geenen, Remy W. F., Mahnken, Andreas H., Brismar, Torkel B., Reimer, Peter   +24 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Prevalence of Type I Allergy to Latex and Type IV Allergy to Rubber Additives in Turkish Healthcare Workers

Dermatology Practical & Conceptual, 2023
Introduction: Glove-induced dermatoses are frequently seen among healthcare workers (HCWs) and are often mistakenly defined as latex allergy. Objectives: To determine the prevalences of (i) the symptoms of immediate type hypersensitivity reactions ...
Hasan Aksoy, Necmettin Akdeniz, Fatma Karakurt   +2 more
doaj   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

Advanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio, Wei Xuan Wilson Loo, Yan Shan Loo, Wen Xin Tan, Hui Xuan Lim, Huitao Liu, Chen Seng Ng   +6 more
wiley   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Case series of sebelipase alfa hypersensitivity reactions and successful sebelipase alfa rapid desensitization

JIMD Reports, 2019
Allergic immune‐mediated hypersensitivity reactions are known potential complications of enzyme replacement therapy. Sebelipase alfa, recombinant lysosomal acid lipase (LAL), is a potentially life‐altering treatment for patients with LAL deficiency ...
Michelle F. Huffaker, Anne Y. Liu, Gregory M. Enns, Suresh Vijay, Antonio J. Amor, N. Franklin Adkinson Jr   +5 more
doaj   +1 more source

Consensus clinical scoring for suspected perioperative immediate hypersensitivity reactions

, 2019
Background Grading schemes for severity of suspected allergic reactions have been applied to the perioperative setting, but there is no scoring system that estimates the likelihood that the reaction is an immediate hypersensitivity reaction.
Savic, L. C., Platt, P. R., Clarke, Russel C., Mertes, P. M., Hepner, DL, Garvey, L. H., Garvey, Lene Heise, Cooke, P. J., Hepner, David L., Marshall, S. D., Hopkins, P. M., Kopac, P., Ebo, D. G., Krøigaard, M., Savic, LC, Volcheck, GW, Volcheck, G. W., Rose, MA, Sabato, V., Dewachter, P, Guttormsen, Anne Berit, Kolawole, H., Garvey, LH, Hopkins, Philip M., Garcez, T., Ebo, DG, Ebo, Didier G., Savic, S, Dewachter, Pascale, Ebo, Didier, Takazawa, T., Sabato, V, Voltolini, S, Sabato, Vito, Laguna, JJ, Savic, S., Clarke, R. C., Guttormsen, AB, Garcez, T, Takazawa, T, Hepner, D. L., Sadleir, P. H. M., Sadleir, PHM, Kroigaard, M., Krøigaard, M, Clarke, RC, Kolawole, H, Dewachter, P., Kopac, P, Marshall, SD, Garcez, Tomaz, Khan, D. A., Rose, M. A., Kopač, Peter, Mertes, PM, Voltolini, S., Laguna, J. J., Cooke, Peter J., Cooke, PJ, Khan, DA, Sadleir, P. H.M., Platt, Peter R., Hopkins, PM, Guttormsen, A. B., Platt, PR   +64 more
core   +1 more source

Distinct Neuropsychiatric Profiles Associated With 17p11.2 Deletions and RAI1 Variants in Smith–Magenis Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Smith–Magenis syndrome (SMS) results from either a recurrent 17p11.2 deletion or pathogenic variants in the retinoic acid induced 1 gene (RAI1). While neurodevelopmental impairment and behavioral dysregulation are well recognized, systematic genotype‐stratified analyses across psychiatric domains remain limited.
Albin Blanc, Christophe Nemos, Céline Bonnet, Mathilde Renaud, Sandra Chapuis, Pauline Boiroux, Marie‐Noëlle Babinet, Caroline Demily   +7 more
wiley   +1 more source

HLA-DRB1 is associated with cefaclor-induced immediate hypersensitivity

World Allergy Organization Journal
Background: Drug-induced hypersensitivity such as anaphylaxis is an important cause of drug-related morbidity and mortality. Cefaclor is a leading cause of drug induced type I hypersensitivity in Korea, but little is yet known about genetic biomarkers to
So-Young Park, MD, PhD, So Young Park, MD, PhD, Sujin Seo, BS, Hyouk-Soo Kwon, MD, PhD, Seung-Hyun Kim, PhD, Sae-Hoon Kim, MD, PhD, Hye-Kyung Park, MD, PhD, Yoon-Seok Chang, MD, PhD, Cheol-Woo Kim, MD, PhD, Byung Jae Lee, MD, PhD, Hae-Sim Park, MD, PhD, You Sook Cho, MD, PhD, Heung-Bum Oh, PhD, David A. Ostrov, PhD, Sungho Won, PhD, Tae Bum Kim, MD, PhD   +15 more
doaj   +1 more source

Inhibition of Three Novel Radix Scutellariae Extracts on Immediate Hypersensitivity

, 2014
Background: Radix Scutellariae, a few papers reported its pharmacology activities including alleviate small intestines smooth muscles spasm,sedation, antihypertensive effect.
Wang, X, Gao, L, wang, xueyan, Wang, J, Gao, Lei, Shi, Haiyun, Li, X, LI, Xiaorong, Wang, Jiangning, Shi, H   +9 more
core   +1 more source