Results 61 to 70 of about 94,721 (312)
Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]
, 2019 Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A. +5 more
core +1 more source
Advanced Science, EarlyView.Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang +11 more
wiley +1 more source
JIMD Reports, 2019 Allergic immune‐mediated hypersensitivity reactions are known potential complications of enzyme replacement therapy. Sebelipase alfa, recombinant lysosomal acid lipase (LAL), is a potentially life‐altering treatment for patients with LAL deficiency ...
Michelle F. Huffaker +5 more
doaj +1 more source
Specific questionnaire detects a high incidence of intra-operative hypersensitivity reactions
Clinics, 2018 OBJECTIVE: To assess the incidence of intra-operative immediate hypersensitivity reactions and anaphylaxis. METHODS: A cross-sectional observational study was conducted at the Department of Anesthesiology, University of São Paulo School of Medicine ...
Laila S. Garro +8 more
doaj +1 more source
Contact urticaria to giraffe hair [PDF]
, 2005 Background: Immediate-type hypersensitivity to animal proteins is a common problem in people occupationally exposed to animals. Methods: A 19-year-old female working as a voluntary zookeeper in her off-time suffered from hives on her forearms following ...
Herzinger, T. +3 more
core +1 more source
Immediate hypersensitivity to Cryptococcus neoformans [PDF]
Infection and Immunity, 1981 The role of the capsular polysaccharide in anaphylactic reactions to Cryptococcus neoformans was investigated. Groups of mice were sensitized with viable cells of either a moderately encapsulated strain of C. neoformans or a non-encapsulated variant. Anaphylactic reactions were observed in both groups of mice to a similar extent when challenged with ...
Y J, Tang, R, Morelli
openaire +2 more sources
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Contrast Medium Hypersensitivity: A Large Italian Study with Long-Term Follow-Up
Biomedicines, 2022 Hypersensitivity reactions (HRs) to contrast media (CM) are a major problem. We compared differences of HRs to iodinated contrast media (ICM) versus gadolinium-based contrast media (GBCM), collecting data on prevalence, type, latency and severity ...
Eleonora Nucera +7 more
doaj +1 more source
Tb3+‐Doped Glass‐Ceramic Scintillating Plates and Fibers for X‐Ray Imaging and Flexible Detection
Advanced Science, EarlyView.A Tb3+‐doped glass‐ceramic scintillator, with controlled Ba2GdF7 nanocrystal precipitation, was developed through a rational design strategy guided by phase diagrams and molecular dynamics simulations. The obtained material exhibits a high light yield of 41 800 photons/MeV (418%/BGO), a spatial resolution of 25.3 lp/mm, and exceptional thermal ...
Songxuan Liu +6 more
wiley +1 more source
Inter-strain differences of serotonergic inhibitory pain control in inbred mice [PDF]
, 2010 Background: Descending inhibitory pain control contributes to the endogenous defense against chronic pain and involves noradrenergic and serotonergic systems.
Wijnvoord, Nina +5 more
core +2 more sources