Sporothrix brasiliensis Causing Atypical Sporotrichosis in Brazil: A Systematic Review
Journal of FungiZoonotic sporotrichosis, a subcutaneous mycosis caused by Sporothrix brasiliensis, has become hyperendemic and a serious public health issue in Brazil and an emerging disease throughout the world.
Vanice Rodrigues Poester +6 more
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Intertwined Orders in Heavy-Fermion Superconductor CeCoIn$_5$
, 2016 The appearance of spin-density-wave (SDW) magnetic order in the low-temperature and high-field corner of the superconducting phase diagram of CeCoIn$_5$ is unique among unconventional superconductors.
Bauer, Eric D. +7 more
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Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire [PDF]
, 2012 Idiosyncratic adverse drug reactions are unpredictable, dose independent and potentially life threatening; this makes them a major factor contributing to the cost and uncertainty of drug development. Clinical data suggest that many such reactions involve
A. Lucas +47 more
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The complexity of T cell–mediated penicillin hypersensitivity reactions [PDF]
, 2020 Shawn J. R. Goh +4 more
openalex +1 more source
Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant Glioma
Advanced Science, EarlyView.IDH‐mutant gliomas exhibit sensitivity to PARP inhibitors (PARPi) owing to oncometabolite 2‐HG‐induced DNA repair defects. PARPi treatment induces resistance by upregulating Prickle4, which promotes VEGF‐driven angiogenesis. Combining PARPi veliparib with anti‐angiogenic lenvatinib blocks this pathway, causing tumor regression and prolonged survival in
Ju Yang +16 more
wiley +1 more source
Evaluation of aesthetic integration between composite restorations and natural tooth in NCCL: a case report [PDF]
, 2015 NCCL (non carious cervical lesion) is defined as irreversible loss of dental hard tissue that does not involve bacteria. It consists of erosion, attrition, abrasion and abfraction that rarely occur alone.
CORRIDORE, DENISE +6 more
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Training the Fetal Immune System Through Maternal Inflammation-A Layered Hygiene Hypothesis. [PDF]
, 2020 Over the last century, the alarming surge in allergy and autoimmune disease has led to the hypothesis that decreasing exposure to microbes, which has accompanied industrialization and modern life in the Western world, has fundamentally altered the immune
Apostol, April C +2 more
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Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
Advanced Science, EarlyView.Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen +4 more
wiley +1 more source
Mental and emotional health [PDF]
, 2012 Nowadays probably every person came across the term Psychotherapy. It seems, however, not to be so clear what psychotherapy actually means. Besides that, it seems to be not so clear, what a Psychotherapist does and how s/he can assist someone, who
Ohk, Brigitte
core
, 2017 The Japanese success rate for alcoholism treatment is approximately 30%, indicating high relapse rates. Although “difficulty in life” is thought to contribute to alcoholics’ relapse, the characteristics of the phenomenon are unknown.
Ito, Keiko
core +3 more sources