Results 91 to 100 of about 634,412 (379)

A novel splice variant of the DNA-PKcs gene is associated with clinical and cellular radiosensitvity in a xeroderma pigmentosum patient [PDF]

open access: yes, 2009
This article has been made available through the Brunel Open Access Publishing Fund.Background: Radiotherapy-induced DNA double strand breaks (DSB) are critical cytotoxic lesions.
Abbaszadeh, F   +9 more
core  

Understanding alcoholics’ “difficulty in life”: An empirical comparison of alcoholics and nonalcoholics

open access: yes, 2017
The Japanese success rate for alcoholism treatment is approximately 30%, indicating high relapse rates. Although “difficulty in life” is thought to contribute to alcoholics’ relapse, the characteristics of the phenomenon are unknown.
Ito, Keiko
core   +3 more sources

IgE-Mediated Hypersensitivity Reactions to Cannabis in Laboratory Personnel [PDF]

open access: yes, 2011
Background: There have been sporadic reports of hypersensitivity reactions to plants of the Cannabinaceae family (hemp and hops), but it has remained unclear whether these reactions are immunologic or nonimmunologic in nature.
Anibarro B   +17 more
core   +1 more source

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

open access: yesAdvanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle   +9 more
wiley   +1 more source

Erythema multiforme: distinguishing hypersensitivity reactions, drug allergy, or herpes simplex infection [PDF]

open access: yesExploration of Immunology
Cutaneous reactions present a diagnostic challenge, mainly when multiple factors, such as infections, medications, and environmental triggers, contribute to the clinical picture.
Vesna Vukičević Lazarević
doaj   +1 more source

Cough Hypersensitivity Syndrome: A Few More Steps Forward

open access: yesAllergy Asthma and Immunology Research, 2017
Cough reflex is a vital protective mechanism against aspiration, but when dysregulated, it can become hypersensitive. In fact, chronic cough is a significant medical problem with a high degree of morbidity.
W. Song, A. Morice
semanticscholar   +1 more source

Prospective genetic screening decreases the incidence of Abacavir hypersensitivity reactions in the Western Australian HIV cohort study [PDF]

open access: yes, 2005
Abacavir therapy is associated with significant drug hypersensitivity in ∼8% of recipients, with retrospective studies indicating a strong genetic association with the HLA-B*5701 allelle.
Almeida, C.   +5 more
core   +2 more sources

Autonomous Implants

open access: yesAdvanced Materials, EarlyView.
An ideal implant should mimic native tissues such that it can integrate, sense, heal, and continue to function, i.e., be autonomous. Although early, there are good steps taken in this way, e.g., the development of stimuli‐responsive, self‐powering, self‐actuating, self‐healing, self‐regenerating, and self‐aware implants.
Jagan Mohan Dodda   +5 more
wiley   +1 more source

Chlorhexidine Allergy: Current Challenges and Future Prospects

open access: yesJournal of Asthma and Allergy, 2020
Chirawat Chiewchalermsri,1,2 Mongkhon Sompornrattanaphan,3 Chamard Wongsa,3 Torpong Thongngarm3 1Division of Allergy and Clinical Immunology, Department of Medicine, Phramongkutklao Hospital, Bangkok, Thailand; 2Department of Medicine, Panyananthaphikkhu
Chiewchalermsri C   +3 more
doaj  

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