Results 91 to 100 of about 521,930 (421)
International Journal of Gynecological Cancer, 2005 Carboplatin has established an important role in many different cancers. As its use increased, the documented cases of hypersensitivity also picked up. Although the mechanism of these reactions remains unknown, the immediate type of hypersensitivity reaction mediated by IgE may be involved.
S, Sliesoraitis, P J, Chikhale
openaire +2 more sources
Inorganic Nanomaterials Meet the Immune System: An Intricate Balance
Advanced Healthcare Materials, EarlyView.Metal nanomaterials influence the immune responses, such as cytokine production and T‐cell activity. Unintended immune modulation can have significant consequences while its fine‐tuning may transform the oncology care. Within this review, a critical analysis is offered regarding the nano/immune‐interaction and suggests the future research directions to
Gloria Pizzoli +3 more
wiley +1 more source
Severe hypersensitivity reaction to etoposide phosphate: A case report
Clinical Case Reports, 2020 Hypersensitivity to etoposide phosphate has rarely been documented. We report a case of severe hypersensitivity reaction to etoposide phosphate in an old man.
Camille Cotteret +3 more
doaj +1 more source
Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire [PDF]
, 2012 Idiosyncratic adverse drug reactions are unpredictable, dose independent and potentially life threatening; this makes them a major factor contributing to the cost and uncertainty of drug development. Clinical data suggest that many such reactions involve immune mechanisms, and genetic association studies have identified strong linkage between drug ...
arxiv +1 more source
Practical Guidelines for Perioperative Hypersensitivity Reactions.
Journal of investigational allergology & clinical immunology, 2018 Perioperative hypersensitivity reactions constitute a first-line problem for anesthesiologists and allergists. Therefore, hospitals should have a consensus protocol for the diagnosis and management of these reactions.
J. Laguna +11 more
semanticscholar +1 more source
Advanced Materials, EarlyView.This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle +9 more
wiley +1 more source
Case Report: Maintenance of Desensitization to Nebulized Colomycin Over 10 Years
Frontiers in Pediatrics, 2021 Drug desensitization can be achieved successfully by gradual drug dose increases in different protocols. Most protocols are designed to obtain temporal tolerance. The data on long-term maintenance of drug tolerance is scarce.
Justyna Sieber +4 more
doaj +1 more source
Fluctuating local moments, itinerant electrons and the magnetocaloric effect: the compositional hypersensitivity of FeRh [PDF]
, 2014 We describe an ab-initio Disordered Local Moment Theory for materials with quenched static compositional disorder traversing first order magnetic phase transitions. It accounts quantitatively for metamagnetic changes and the magnetocaloric effect. For perfect stoichiometric B2-ordered FeRh, we calculate the transition temperature of the ferromagnetic ...
arxiv +1 more source
Universal Route for the Emergence of Exceptional Points in PT-Symmetric Metamaterials with Unfolding Spectral Symmetries [PDF]
, 2020 We introduce a class of Parity-Time symmetric elastodynamic metamaterials (Ed-MetaMater) whose Hermitian counterpart exhibits a frequency spectrum with unfolding (fractal) symmetries. Our study reveals a scale-free formation of exceptional points (EP) whose density is dictated by the fractal dimension of their Hermitian spectra. Demonstrated in a quasi-
arxiv +1 more source
Hypersensitivity pneumonitis: a complex lung disease
Clinical and Molecular Allergy, 2017 Hypersensitivity pneumonitis (HP), also called extrinsic allergic alveolitis, is a respiratory syndrome involving the lung parenchyma and specifically the alveoli, terminal bronchioli, and alveolar interstitium, due to a delayed allergic reaction.
G. R. Riario Sforza, A. Marinou
semanticscholar +1 more source