Results 121 to 130 of about 509,314 (341)

Pre‐Existing Th1 Immunity Outperforms Age in Predicting Antibody Responses to SARS‐CoV‐2 Inactivated Vaccines

open access: yesAdvanced Science, EarlyView.
Challenging the focus on age, this study finds pre‐existing T helper 1 cells are the key biomarker for predicting antibody response to SARS‐CoV‐2 inactivated vaccines. In both mice and humans, high responders exhibited elevated baseline T helper 1 cells, which correlated with robust humoral immunity, offering crucial guidance for improving vaccine ...
Chanyuan Ye   +12 more
wiley   +1 more source

Antiemesis Corticosteroids Potentiate Checkpoint Blockade Efficacy by Normalizing the Immune Microenvironment in Metastatic Murine Breast Cancer

open access: yesAdvanced Science, EarlyView.
Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin   +19 more
wiley   +1 more source

THE FACTS ABOUT PENICILLIN ALLERGY: A REVIEW

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2010
Hypersensitivity reactions are the major problem in the use of penicillins. Truepenicillin allergy is rare with the estimated frequency of anaphylaxis at 1-5 per 10 000cases of penicillin therapy.
Sanjib Bhattacharya
doaj  

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

open access: yesAdvanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Overcoming PEG Antigenicity: Statistical PEG Isomers Reduce Antibody Binding

open access: yesAdvanced Science, EarlyView.
Conventional poly(ethylene glycol) (PEG) is commonly applied in biomedicine, but is now known to induce antibody formation. Here, it is shown that the development of “randomized PEG” (rPEG) featuring glycidyl methyl ether (GME) comonomers decreased antibody binding.
Mareike Deuker   +5 more
wiley   +1 more source

Systemic hypersensitivity reaction to Omnipaque radiocontrast medium: a case of mini‐DRESS [PDF]

open access: gold, 2016
Christina George   +4 more
openalex   +1 more source

Toward Advanced Degradable Soft Robotics Incorporating Transient Soft Electronics: Materials, Fabrication, and Applications

open access: yesAdvanced Electronic Materials, EarlyView.
Degradable soft robots are gaining attention for applications in various fields such as exploration, healthcare, and security. The integration of transient electronics is essential to enhance their intelligent task‐performing capabilities. This review offers insights into the advancement of soft electronic–robotic systems by providing an overview of ...
Kyung‐Sub Kim   +3 more
wiley   +1 more source

Functional bowel disease : a challenging frontier in gastroenterology [PDF]

open access: yes, 1999
The last 30 years have seen incredible advances in the science and practice of gastroenterology and hepatology. In the 1970s, the fiberoptic endoscopic revolution facilitated the visualization of the mucosa of a large segment of the gastrointestinal ...
Camilleri, Michael
core  

Intrinsic neural stem cell properties define brain hypersensitivity to genotoxic stress [PDF]

open access: gold, 2022
Argyro Kalogeropoulou   +13 more
openalex   +1 more source

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