Results 61 to 70 of about 521,930 (421)

The Development of Hypersensitivity Reactions in the Pediatric Population: A Review [PDF]

open access: yes, 2019
Over the past several years, pediatric allergies have come to the forefront of many studies. Reports of immune-mediated hypersensitivity in younger patients have grown and led to an interest researching the causes of pediatric hypersensitivities.
Burns, Heather
core   +1 more source

Efficacy of a Dissolvable Strip with Calcium Sodium Phosphosilicate (NovaMin®) in Providing Rapid Dentine Hypersensitivity Relief [PDF]

open access: yes, 2019
Objective To evaluate the efficacy of a dissolvable strip containing 15% w/w calcium sodium phosphosilicate (CSPS) (Novamin®) in providing rapid relief from dentine hypersensitivity (DH).
Amini, Pejmon   +4 more
core   +2 more sources

Mas-Related G Protein-Coupled Receptor-X2 (MRGPRX2) in Drug Hypersensitivity Reactions

open access: yesFrontiers in Immunology, 2018
The human ortholog MRGPRX2 and the mice ortholog, Mrgprb2 are activated by basic secretagogues and neurokinins. A number of commonly used small-molecule drugs (e.g., neuromuscular blocking agents, fluoroquinolones, vancomycin) have been recently shown to
G. Porębski   +3 more
semanticscholar   +1 more source

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

open access: yesFEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley   +2 more
wiley   +1 more source

Immune checkpoint inhibitor-induced severe epidermal necrolysis mediated by macrophage-derived CXCL10 and abated by TNF blockade

open access: yesNature Communications
Immune checkpoint inhibitors (ICI) represent new anticancer agents and have been used worldwide. However, ICI can potentially induce life-threatening severe cutaneous adverse reaction (SCAR), such as Stevens-Johnson syndrome/toxic epidermal necrolysis ...
Chun-Bing Chen   +31 more
doaj   +1 more source

Lamiaceae: An Insight on Their Anti-Allergic Potential and Its Mechanisms of Action

open access: yesFrontiers in Pharmacology, 2019
The prevalence of allergic diseases such as asthma, allergic rhinitis, food allergy and atopic dermatitis has increased dramatically in recent decades.
Lee Yen Sim   +2 more
doaj   +1 more source

Nonlinear Response With Dichotomous Noise [PDF]

open access: yesPhys. Rev. E 66, 045603(R) (2002)., 2002
Dichotomous noise appears in a wide variety of physical and mathematical models. It has escaped attention that the standard results for the long time properties cannot be applied when unstable fixed points are crossed in the asymptotic regime. We show how calculations have to be modified to deal with these cases and present as a first application full ...
arxiv   +1 more source

The Three R\u27s of Delayed Hypersensitivity [PDF]

open access: yes, 1974
Delayed hypersensitivity is one of several immune responses initiated by thymus-derived (T) lymphocytes. The mononuclear infiltrate of delayed hypersensitivity is a collaborative phenomenon between T lymphocytes and monocytes.
Horwitz, David
core   +1 more source

Immediate-Type Hypersensitivity to Succinylated Corticosteroids [PDF]

open access: yes, 2011
Background: Despite their frequent use, systemic corticosteroids have rarely elicited immediate-type reactions. Objective: We report two male patients, aged 26 and 70 years, respectively, with severe immediate-type hypersensitivity secondary to the ...
Przybilla, Bernhard   +3 more
core   +1 more source

EAACI/ENDA Position Paper: Diagnosis and management of hypersensitivity reactions to non‐steroidal anti‐inflammatory drugs (NSAIDs) in children and adolescents

open access: yesPediatric Allergy and Immunology, 2018
Non‐steroidal anti‐inflammatory drugs (NSAIDs) are commonly used in the pediatric population as antipyretics/analgesics and anti‐inflammatory medications.
M. Kidon   +11 more
semanticscholar   +1 more source

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