Results 41 to 50 of about 371,617 (308)

Viral Infections and Cutaneous Drug-Related Eruptions

Frontiers in Pharmacology, 2021
In the general population, up to 10% of children treated by antibiotics have cutaneous adverse drug reaction, but allergy is confirmed in less than 20% of patients.
Eleonora Anci, Camille Braun, Camille Braun, Annalisa Marinosci, Frédérique Rodieux, Elise Midun, Elise Midun, Maria-Jose Torres, Jean-Christoph Caubet   +8 more
doaj   +1 more source

HLA-B*5701 screening for hypersensitivity to Abacavir [PDF]

, 2008
Background Hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele. This study was designed to establish the effectiveness of prospective HLA-B*5701 screening to prevent the hypersensitivity reaction to ...
Jagel-Guedes, E., Kozyrev, O., Phillips, E., Fitch, N., Thorborn, D., Molina, J-M, Hughes, A., Cid, J.F., Rugina, S., Nolan, D., Carosi, G., Hay, P., Ryan, S., Tomazic, J., Hughes, S., Benbow, A., Mallal, S., Workman, C.   +17 more
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Prevalence and cumulative incidence of food hypersensitivity in the first 3 years of life [PDF]

, 2007
Background: prevalence and incidence of food hypersensitivity (FHS) and its trends in early childhood are unclear. Methods: a birth cohort born on the Isle of Wight (UK) between 2001 and 2002 was followed-up prospectively.
Grundy, J., K. Voigt, Clayton, C., Venter, Carina, Dean, T., Higgins, B., Arshad, S., Pereira, B., B. Higgins, Arshad, Syed Hasan, Venter, C., Grundy, Jane D., Clayton, C.B., C. B. Clayton, T. Dean, Dean, Taraneh, Voigt, K., Higgins, Bernard, S. H. Arshad, C. Venter, B. Pereira, Dean, Tara, J. Grundy   +22 more
core   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Hypersensitivity to paroxetine

Allergologia et Immunopathologia, 2006
The increasingly extensive use of selective serotonin reuptake inhibitors will probably increase the number of cases of cutaneous reactions due to these drugs. This report describes a case of generalized exanthema due to paroxetine. Positive results to patch tests indicated delayed hypersensitivity.
María T Soto, Mera, Beatriz Veleiro, Pérez, Rosario Olivera, Fernández, José F Filgueira, Iglesias   +3 more
openaire   +2 more sources

Drug hypersensitivity: flare-up reactions, cross-reactivity and multiple drug hypersensitivity

, 2011
In drug hypersensitivity, change of drug treatment and continuation with a new drug may result in reappearance of drug hypersensitivity symptoms. This is not uncommon in patients with chronic infections requiring continued and long-lasting antibiotic ...
Pichler, Werner J, Daubner, Barbara, Barbara DAUBNER, Tom KAWABATA, Werner J. PICHLER, Kawabata, Tom, Daubner B, Kawabata T, Pichler WJ, Pichler, Werner Joseph   +9 more
core   +1 more source

Clarithromycin hypersensitivity in children: Is there a link with β‐lactam hypersensitivity?

, 2021
Background: Clarithromycin hypersensitivity is reported as the most common cause of non-beta-lactam antibiotic allergy in children. Clarithromycin is frequently prescribed in cases of suspected beta-lactam hypersensitivity.
Hizli Demirkale, Zeynep, Yucel, Esra, Ozdemir, Cevdet, Esra Yucel, Cevdet Ozdemir, Zeynep Hizli Demirkale, Nermin Guler, Guler, Nermin, Sevgi Sipahi Cimen, Tamay, Zeynep Ülker, Suleyman, Ayse, Zeynep Ulker Tamay, Ayse Suleyman, Sipahi Cimen, Sevgi   +13 more
core   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Allergic asthma and rhinitis comorbidity [PDF]

Vojnosanitetski Pregled, 2015
nema
Zvezdin Biljana, Hromiš Sanja, Kolarov Violeta, Milutinov Senka, Zarić Bojan, Jovančević Ljiljana, Ilić Miroslav   +6 more
doaj   +1 more source