Results 61 to 70 of about 358,537 (259)

Perfuração dos lóbulos das orelhas como fator de risco para o desenvolvimento de alergia de contato ao níquel Ear piercing as a risk factor for contact allergy to nickel

Jornal de Pediatria, 2010
OBJETIVOS: Determinar a prevalência da alergia de contato aos metais em crianças que frequentam um centro de saúde e caracterizar o subgrupo com alergia em relação aos fatores de risco.
Marilda H. T. Brandão, Bernardo Gontijo, Marcela A. Girundi, Maria C. M. de Castro   +3 more
doaj   +1 more source

High sensitivity of human leukocyte antigen–B*5701 as a marker for immunologically confirmed abacavir hypersensitivity in white and black patients [PDF]

, 2008
Background. Although the human leukocyte antigen (HLA)-B*5701 is highly associated with a hypersensitivity reaction (HSR) to abacavir (ABC), variable sensitivities have been reported when clinical data alone have been used to define an ABC HSR.
Stancil, B., Balu, R., Mosteller, M., Wannamaker, P., Phillips, E.J., Saag, M., Burman, W., Brothers, C., Brachman, P., Hughes, A., Sutherland‐Phillips, D., Martorell, C., Mallal, S., Shaefer, M.   +13 more
core  

Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity [PDF]

, 2005
Langerhans cells (LC) form a unique subset of dendritic cells ( DC) in the epidermis but so far their in vivo functions in skin immunity and tolerance could not be determined, in particular in relation to dermal DC ( dDC).
Clausen, B.E., Inaba, K, Jung, S, Erwin van Rijn, van Rijn, E., Ralph M. Steinman, Clausen, Björn E., Inaba, K., Jung, S., van Rijn, Erwin, Steffen Jung, Clausen, BE, Kapsenberg, Martien L., Kayo Inaba, Inaba, Kayo, van Rijn, E, Bennett, CL, Kapsenberg, ML, Kapsenberg, M.L., Björn E. Clausen, Martien L. Kapsenberg, Jung, Steffen, Steinman, RM, Bennett, C., Steinman, R.M., Bennett, Clare L., Steinman, Ralph M., Clare L. Bennett   +27 more
core   +2 more sources

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

The Efficacy of Selected Desensitizing OTC Products: A Systematic Review. [PDF]

, 2014
Licensed by the Creative Commons Attribution LicenseObjectives. The aim of the present study was to review the published literature in order to identify relevant studies for inclusion and to determine whether there was any evidence on the clinical ...
Talioti, E, Hill, R, Gillam, DG
core   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Modulation of the Bovine Delayed-Type Hypersensitivity Responses to Defined Mycobacterial Antigens by a Synthetic Bacterial Lipopeptide [PDF]

, 2003
The use of defined protein and peptide antigens can overcome specificity limitations of purified protein derivatives in the detection of bovine tuberculosis when the antigens are used in blood-based tests. Since the use of these specific antigens as skin
Howard, CJ, Hewinson, R. G., Vordermeier, H.M., Clifford, D., Hope, Jayne; id_orcid, Whelan, A O   +5 more
core  

FGF13 Deficiency Ameliorates Paclitaxel‐Induced Neuropathic Pain by Inhibiting VASH1‐Mediated Microtubule Detyrosination to Promote Mitophagy

Advanced Science, EarlyView.
FGF13 is upregulated in DRG neurons of PIPNP model mice. DRG neuron‐specific knockout of FGF13 ameliorates PIPNP symptoms. Mechanistically, FGF13 potentiates microtubule detyrosination by promoting VASH1 binding to microtubules. FGF13 knockout suppresses VASH1‐mediated microtubule detyrosination and promotes α‐tubulin tyrosination.
Yiming Dong, Yidan Wang, Simeng Lv, Zishan Dong, Kaixi Zhi, Xiuhua Guo, Xuyan Li, Ruoxi Yu, Yiyi Zhang, Siyuan Cheng, Chuan Wang   +10 more
wiley   +1 more source

Mechanisms Responsible for Serotonin Vascular Reactivity Sex Differences in the Internal Mammary Artery

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background The increased adverse cardiac events in women undergoing coronary artery bypass grafting are multifactorial and may include clinical, psychosocial, and biological factors.
Victor Lamin, Amenah Jaghoori, Rachel Jakobczak, Irene Stafford, Tamila Heresztyn, Michael Worthington, James Edwards, Fabiano Viana, Robert Stuklis, David P. Wilson, John F. Beltrame   +10 more
doaj   +1 more source

Duodenal administered seal oil for patients with subjective food hypersensitivity: an explorative open pilot study [PDF]

, 2010
Short-term duodenal administration of n-3 polyunsaturated fatty acid (PUFA)-rich seal oil may improve gastrointestinal complaints in patients with subjective food hypersensitivity, as well as joint pain in patients with inflammatory bowel disease (IBD ...
Bjørkkjær, Tormod, null Gregersen, Lind, Ragna Anne, Berstad, Arnold, Valeur, Jørgen, Lied, Gülen Arslan, Gregersen, Kine   +6 more
core   +1 more source