Results 21 to 30 of about 294,169 (269)

HLA Association with Drug-Induced Adverse Reactions

open access: yesJournal of Immunology Research, 2017
Adverse drug reactions (ADRs) remain a common and major problem in healthcare. Severe cutaneous adverse drug reactions (SCARs), such as Stevens–Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) with mortality rate ranges from 10% to more than 30 ...
Wen-Lang Fan   +6 more
doaj   +1 more source

Vaccination against COVID-19 in patients with allergy: experience of the allergological center in Dnipro

open access: yesMedičnì Perspektivi, 2023
Vaccination against COVID-19 is the main global preventive measure in the fight against SARS-CoV-2. As the COVID-19 vaccine will be administered to billions of individuals worldwide during the pandemic, there exists a reasonable fear of severe adverse ...
Ye.M. Dytiatkovska   +3 more
doaj   +1 more source

Incidence of teicoplanin adverse drug reactions among patients with vancomycin-associated adverse drug reactions and its risk factors [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2020
Background/Aims Teicoplanin can be used as an alternative to vancomycin when treating beta-lactam-resistant gram-positive bacterial infections. Both vancomycin and teicoplanin are associated with relatively high rates of adverse drug reactions (ADRs ...
Byung-Keun Kim   +5 more
doaj   +1 more source

HLA Associations and Clinical Implications in T-Cell Mediated Drug Hypersensitivity Reactions: An Updated Review

open access: yesJournal of Immunology Research, 2014
T-cell mediated drug hypersensitivity reactions may range from mild rash to severe fatal reactions. Among them, drug reaction with eosinophilia and systemic symptoms (DRESS) or drug-induced hypersensitivity syndrome (DIHS), Stevens-Johnson syndrome ...
Chi-Yuan Cheng   +5 more
doaj   +1 more source

Severe cutaneous adverse reactions associated with systemic antibiotics in acne vulgaris: a systematic review

open access: yesJournal of Dermatological Treatment
Background Acne vulgaris (AV) is an inflammatory disorder of the pilosebaceous unit commonly managed with systemic antibiotics. Since antibiotics are known triggers of severe cutaneous adverse drug reaction (SCARs), patients with AV receiving prolonged ...
Ivan Arni C. Preclaro   +4 more
doaj   +1 more source

A Novel System to Diagnose Cutaneous Adverse Drug Reactions Employing the Cellscan—Comparison with Histamine Releasing Test and Inf-γ Releasing Test

open access: yesClinical and Developmental Immunology, 2005
Background: There are several mechanisms to describe allergic drug reactions yet the methods to diagnose them are limited.
Ilan Goldberg   +9 more
doaj   +1 more source

Hypersensitivity to pyrazolones [PDF]

open access: yesThorax, 2000
To the allergologist, hypersensitivity to drugs means immunological drug reactions as classified in the Gell and Coombs system. To others, it may also include non-dose related adverse drug reactions including the non-immune mediated idiosyncratic drug reactions (type B).
openaire   +2 more sources

Clinical Characteristics and Disease Burden of Patients with Moderate-to-Severe Generalized Pustular Psoriasis Flares in Taiwan

open access: yesDermatology and Therapy
Introduction Generalized pustular psoriasis (GPP) is a rare and severe psoriasis subtype characterized by the rapid onset of coalescing sterile pustules over broad body areas and systemic inflammation.
Chun-Wei Lu   +10 more
doaj   +1 more source

Galanin suppresses visceral afferent responses to noxious mechanical and inflammatory stimuli

open access: yesPhysiological Reports, 2020
Galanin is a neuropeptide expressed by sensory neurones innervating the gastrointestinal (GI) tract. Galanin displays inhibitory effects on vagal afferent signaling within the upper GI tract, and the goal of this study was to determine the actions of ...
Toni S. Taylor   +5 more
doaj   +1 more source

Viral Infections and Cutaneous Drug-Related Eruptions

open access: yesFrontiers in Pharmacology, 2021
In the general population, up to 10% of children treated by antibiotics have cutaneous adverse drug reaction, but allergy is confirmed in less than 20% of patients.
Eleonora Anci   +8 more
doaj   +1 more source

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