Drug hypersensitivity represents an immune-mediated reaction to a drug. Although several drug hypersensitivity reactions are confined to the skin and rather mild, some may be life threatening and also involve further organs such as liver, kidney and bone marrow. The exact pathogenesis of many drug hypersensitivity reactions is still obscure.
Yawalkar, N, Yawalkar N
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Subjective food hypersensitivity: assessment of enterochromaffin cell markers in blood and gut lavage fluid [PDF]
Kine Gregersen1,2, Jørgen Valeur1,3, Kristine Lillestøl1,3, Livar Frøyland2, Pedro Araujo2, Gülen Arslan Lied1,3, Arnold Berstad1,31Institute of Medicine, University of Bergen, 2National Institute of Nutrition ...
Gregersen K +7 more
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Prospective genetic screening decreases the incidence of Abacavir hypersensitivity reactions in the Western Australian HIV cohort study [PDF]
Abacavir therapy is associated with significant drug hypersensitivity in ∼8% of recipients, with retrospective studies indicating a strong genetic association with the HLA-B*5701 allelle.
McKinnon, E. +11 more
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Assessment of drug hypersensitivity with non-irritating concentrations of antibacterial agents for allergic skin tests: a review [PDF]
Hypersensitivity reactions to antibiotics are common with a prevalence of 6-10% of all adverse reactions. There is a lack of guidelines and standardization of skin tests for the screening of hypersensitivity to all antibiotics, in terms of the ...
M. C., Shivamurthy +2 more
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Pain hypersensitivity and spinal nociceptive hypersensitivity in chronic pain: prevalence and associated factors. [PDF]
Hypersensitivity of pain pathways is considered a relevant determinant of symptoms in chronic pain patients, but data on its prevalence are very limited. To our knowledge, no data on the prevalence of spinal nociceptive hypersensitivity are available. We
Andersen, Ole Kæseler; id_orcid +15 more
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Relationship between Sympathetic Skin Responses and Auditory Hypersensitivity to Different Auditory Stimuli [PDF]
[Purpose] Auditory hypersensitivity has been widely reported in patients with autism spectrum disorders. However, the neurological background of auditory hypersensitivity is currently not clear.
Fujihara, Saori +8 more
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Case Report: Maintenance of Desensitization to Nebulized Colomycin Over 10 Years
Drug desensitization can be achieved successfully by gradual drug dose increases in different protocols. Most protocols are designed to obtain temporal tolerance. The data on long-term maintenance of drug tolerance is scarce.
Justyna Sieber +4 more
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Neonatal lupus erythematosus presenting as Stevens-Johnson syndrome
Neonatal lupus erythematosus (NLE) is a rare acquired condition caused by the transplacental passage of maternal autoantibodies. It is characterized by cutaneous, cardiac, hepatobiliary, hematological and neurological involvement.
Ren-Feng Liu +4 more
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Case study of boy with submucosal cleft palate, developmental dysphasia and eating disorder
The case study examines the therapy, utilising interdisciplinary diagnostics, of a boy with submucosal cleft palate, combined with developmental dysphasia, an eating disorder and hypersensitivity of the orofacial area. The aim of the case study was to hi-
Dana Zemčíková
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Immediate hypersensitivity and delayed hypersensitivity to Clopidogrel
Clopidogrel is a new antiplatelet prescribed for the secondary prevention of atherosclerotic events. The literature shows that the clinical manifestations of clopidogrel hypersensitivity include urticaria1, skin rash2-4, and angioedema5. The precise immunological mechanism underlying clopidogrel hypersensitivity has not been established.
D, Gutiérrez-Fernández +4 more
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