An Anterior Cingulate Cortex-Anterior Insular Cortex Glutamatergic Circuit Gates Stress-Induced Visceral Hypersensitivity and Anxiety via Ionotropic Glutamate Receptors Trafficking. [PDF]
This study identifies an anterior cingulate cortex (ACC) to anterior insular cortex (AIC) glutamatergic (Glu) circuit that gates stress induced visceral hypersensitivity and anxiety. Circuit activation induces both phenotypes, whereas inhibition relieves them.
Wang J +8 more
europepmc +2 more sources
Prospective genetic screening decreases the incidence of Abacavir hypersensitivity reactions in the Western Australian HIV cohort study [PDF]
Abacavir therapy is associated with significant drug hypersensitivity in ∼8% of recipients, with retrospective studies indicating a strong genetic association with the HLA-B*5701 allelle.
McKinnon, E. +11 more
core +2 more sources
Assessment of drug hypersensitivity with non-irritating concentrations of antibacterial agents for allergic skin tests: a review [PDF]
Hypersensitivity reactions to antibiotics are common with a prevalence of 6-10% of all adverse reactions. There is a lack of guidelines and standardization of skin tests for the screening of hypersensitivity to all antibiotics, in terms of the ...
M. C., Shivamurthy +2 more
core +1 more source
Peripheral and central mechanisms in acid induced visceral pain hypersensitivity in the human oesophagus [PDF]
PhDIntroduction: Gastro-oesophageal reflux disease (GORD) affects 40% of Western populations. Many symptoms persist despite the resolution of inflammation or acid exposure.
Chua, Yang Chong
core +4 more sources
Immediate-Type Hypersensitivity to Succinylated Corticosteroids [PDF]
Background: Despite their frequent use, systemic corticosteroids have rarely elicited immediate-type reactions. Objective: We report two male patients, aged 26 and 70 years, respectively, with severe immediate-type hypersensitivity secondary to the ...
Raewer, Helen-Caroline +7 more
core +1 more source
Subjective food hypersensitivity: assessment of enterochromaffin cell markers in blood and gut lavage fluid [PDF]
Background: Food hypersensitivity is commonly suspected, but seldom verified. Patients with subjective food hypersensitivity suffer from both intestinal and extraintestinal health complaints. Abnormalities of the enterochromaffin cells may play a role in
null Gregersen +13 more
core +2 more sources
Case Report: Maintenance of Desensitization to Nebulized Colomycin Over 10 Years
Drug desensitization can be achieved successfully by gradual drug dose increases in different protocols. Most protocols are designed to obtain temporal tolerance. The data on long-term maintenance of drug tolerance is scarce.
Justyna Sieber +4 more
doaj +1 more source
Neonatal lupus erythematosus presenting as Stevens-Johnson syndrome
Neonatal lupus erythematosus (NLE) is a rare acquired condition caused by the transplacental passage of maternal autoantibodies. It is characterized by cutaneous, cardiac, hepatobiliary, hematological and neurological involvement.
Ren-Feng Liu +4 more
doaj +1 more source
Case study of boy with submucosal cleft palate, developmental dysphasia and eating disorder
The case study examines the therapy, utilising interdisciplinary diagnostics, of a boy with submucosal cleft palate, combined with developmental dysphasia, an eating disorder and hypersensitivity of the orofacial area. The aim of the case study was to hi-
Dana Zemčíková
doaj +1 more source
Background: The present study aims to assess area of open dentinal tubules by use of diode laser and electrode alone and in combination with hydroxyapatite powder and strontium chloride powder by using the scanning electron microscope (SEM).
Chitra Laxmikant Patil +1 more
doaj +1 more source

