Results 71 to 80 of about 648,308 (386)

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

The Three R\u27s of Delayed Hypersensitivity [PDF]

, 1974
Delayed hypersensitivity is one of several immune responses initiated by thymus-derived (T) lymphocytes. The mononuclear infiltrate of delayed hypersensitivity is a collaborative phenomenon between T lymphocytes and monocytes.
Horwitz, David
core   +1 more source

Prospective genetic screening decreases the incidence of Abacavir hypersensitivity reactions in the Western Australian HIV cohort study [PDF]

, 2005
Abacavir therapy is associated with significant drug hypersensitivity in ∼8% of recipients, with retrospective studies indicating a strong genetic association with the HLA-B*5701 allelle.
Almeida, C., Mallal, S., Martin, A., McKinnon, E., Nolan, D., Rauch, A.   +5 more
core   +2 more sources

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

Arthritis Care &Research, EarlyView.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla, Robert Lafyatis, Kevin F. Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J. Kass   +13 more
wiley   +1 more source

Efficacy and safety of indigo naturalis oil extract (Lindioil ointment) for the treatment of atopic dermatitis: a randomized, crossover, evaluator-blinded, controlled trial

Frontiers in Pharmacology
IntroductionLindioil ointment or its compound formulations are commonly used traditional Chinese medicine practitioners to treat adult eczema or localized dermatitis.
Chin-Yi Yang, Chin-Yi Yang, Chin-Yi Yang, Chin-Yi Yang, Chun-Bing Chen, Chun-Bing Chen, Chun-Bing Chen, Chun-Bing Chen, Chun-Wei Lu, Chun-Wei Lu, Chun-Wei Lu, Min-Hui Chi, Min-Hui Chi, Min-Hui Chi, Min-Hui Chi, Jennifer Wu, Jennifer Wu, Jennifer Wu, Wen-Hung Chung, Wen-Hung Chung, Wen-Hung Chung, Wen-Hung Chung, Be-Han Lee, Yin-Ku Lin, Yin-Ku Lin   +24 more
doaj   +1 more source

SoundFields: A Virtual Reality Home-Based Intervention for Auditory Hypersensitivity Experienced by Autistic Children

Applied Sciences, 2023
Previous studies have shown that autistic people often display atypical responses when processing sensory information, with particular prevalence within the auditory domain.
Sarah Parkinson, Sophie Schumann, Amelia Taylor, Clare Fenton, Gavin Kearney, Megan Garside, Daniel Johnston   +6 more
doaj   +1 more source

Mas-Related G Protein-Coupled Receptor-X2 (MRGPRX2) in Drug Hypersensitivity Reactions

Frontiers in Immunology, 2018
The human ortholog MRGPRX2 and the mice ortholog, Mrgprb2 are activated by basic secretagogues and neurokinins. A number of commonly used small-molecule drugs (e.g., neuromuscular blocking agents, fluoroquinolones, vancomycin) have been recently shown to
G. Porębski, K. Kwiecien, Magdalena Pawica, M. Kwitniewski   +3 more
semanticscholar   +1 more source

Long‐Term Opioids in Gout: A Matched Cohort Study From the Veterans Health Administration

Arthritis Care &Research, EarlyView.
Objective Though used frequently to treat flare, risk of long‐term opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed long‐term opioids over time.
Lindsay N. Helget, Bryant R. England, Punyasha Roul, Harlan Sayles, Tuhina Neogi, James R. O'Dell, Joshua F. Baker, Ted R. Mikuls   +7 more
wiley   +1 more source

Perfuração dos lóbulos das orelhas como fator de risco para o desenvolvimento de alergia de contato ao níquel Ear piercing as a risk factor for contact allergy to nickel

Jornal de Pediatria, 2010
OBJETIVOS: Determinar a prevalência da alergia de contato aos metais em crianças que frequentam um centro de saúde e caracterizar o subgrupo com alergia em relação aos fatores de risco.
Marilda H. T. Brandão, Bernardo Gontijo, Marcela A. Girundi, Maria C. M. de Castro   +3 more
doaj   +1 more source

Regulatory T Cell-Targeted Immunomodulatory Therapy for Long-Term Clinical Improvement of Atopic Dermatitis: Hypotheses and Perspectives

Life, 2023
Atopic dermatitis (AD) is a chronically relapsing inflammatory skin disorder characterized by itching and eczematous lesions. It is often associated with a personal or familial history of allergic diseases. Allergic inflammation induced by immunoglobulin
Dong-Ho Nahm
doaj   +1 more source