Results 51 to 60 of about 255,323 (285)

The Distribution of Complement Proteins in Soft and Hard Coronas Impacts Macrophage Uptake of Nanoparticles

Advanced Healthcare Materials, EarlyView.
Protein corona plays a critical role in the biological behavior of nanoparticles. This study investigates the distribution of complement proteins in soft corona and their impact on the macrophage uptake of polymer nanoparticles. It underlines the significance of soft corona investigation for understanding in vivo performance of nanomedicines.
Ying Qiu, Tianchang He, Chunjie Miao, Xinyang Shi, Yuanyuan Niu, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang   +8 more
wiley   +1 more source

SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children [PDF]

, 2018
Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs).
Arasi, Stefania, Barni, Simona, Bottau, Paolo, Caffarelli, Carlo, Caimmi, Davide, Caimmi, Silvia, Cardinale, Fabio, Comberiati, Pasquale, Crisafulli, SEBASTIANO GIUSEPPE, Di Mauro, Dora, Diaferio, Lucia, Duse, Marzia, Franceschini, Fabrizio, Liotti, Lucia, Marseglia, Gianluigi, Mastrorilli, Carla, Mori, Francesca, Paravati, Francesco, Pelosi, Umberto, Saretta, Francesca   +19 more
core   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Hypersensitivity reactions with first-line antituberculosis drugs and outcomes of rapid desensitizations

World Allergy Organization Journal
Background: Data about drug hypersensitivity reactions with first-line antituberculosis drugs and their management is limited. Rapid drug desensitization seems to be an appropriate management. Objective: Evaluate the efficacy of the rapid desensitization
Gozde Koycu Buhari, MD, Ferda Oner Erkekol, MD, Ilkay Koca Kalkan, MD, Hale Ates, MD, Gurgun Tugce Vural Solak, MD, Ozgur Akkale, MD, Kurtulus Aksu, MD   +6 more
doaj   +1 more source

Delayed Hypersensitivity Reaction after Nipple Tattooing: A Novel Case Report

Plastic and Reconstructive Surgery, Global Open, 2019
Summary:. We present a patient who underwent bilateral 3-dimensional (3D) nipple tattooing for nipple areolar reconstruction after implant-based breast reconstruction for breast cancer.
Walter J. Joseph, MD, Eva Roy, BS, Guy M. Stofman, MD   +2 more
doaj   +1 more source

Amine‐Functionalized Chitosan/dECM Composite Promotes Cutaneous Regeneration and Hair Follicle Activation by Regulating Oxidative Stress and Inflammation

Advanced Healthcare Materials, EarlyView.
An amine‐functionalized chitosan and hydrolyzed dECM composite promotes cutaneous regeneration by modulating oxidative stress and inflammatory pathways. The material accelerates wound closure and stimulates hair follicle activation in UV‐damaged cutaneous tissue.
Yu‐Jin Kim, Seokheon Hong, Jae Hwi Lee, Jongmin Lee, Jae Jun Kang, Jiseon Bae, Jino Kim, Dong‐Hwee Kim, Jin Yoo, Mi Sun Cha, Su Hee Kim, Youngmee Jung   +11 more
wiley   +1 more source

Severe Hypersensitivity Reactions with Oral Manifestations: Case Reports on Stevens-Johnson Syndrome and DRESS Syndrome

Journal of Pharmacy and Bioallied Sciences
Stevens-Johnson syndrome (SJS) and Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome are rare conditions, representing severe hypersensitivity reactions with significant oral presentations.
Sura A. A. Fuoad Al-Bayati
doaj   +1 more source

A Case Report on a Severe Anaphylaxis Reaction to Gadolinium-Based MR Contrast Media

대한영상의학회지, 2017
Acute hypersensitivity reactions to gadolinium-based magnetic resonance (MR) contrast media have been shown to have a much lower incidence and they are generally milder in terms of severity than acute adverse reactions associated with the use of ...
Juil Park, Tae Hyung Kim, Chang Min Park, Soon Ho Yoon, Whal Lee, Hye-Ryun Kang, Young Hun Choi   +6 more
doaj   +1 more source

Psychologic modulation of the human immune response to varicella zoster [PDF]

, 1985
Psychoimmunology, the interrelationship between the brain/mind/psyche and the immune system, is now an established area of scientific research. Based on prior investigations we hypothesized that an experienced meditator could affect her delayed ...
Marmer, D. J., McKenzie, J. M., Smith Jr., G. R., Steele, R. W.   +3 more
core   +1 more source