Results 101 to 110 of about 14,767 (235)

What Do Patient‐Reported Sleep Measures Assess? A Content Analysis

Journal of Sleep Research, EarlyView.
ABSTRACT Current systematic review analysed the content of generic patient‐reported sleep measures (PRSMs) using (1) the International Classification of Functioning, Disability and Health (ICF) and (2) semantic analysis. A literature search identified 27 PRSMs applicable across multiple sleep disorders.
Marie De Bruecker, Elke Veirman, An Mariman, Dirk A. Pevernagie, Katrien B. C. Hertegonne, Fré A. Bauters, Dimitri M. L. Van Ryckeghem, Geert Crombez   +7 more
wiley   +1 more source

Postmortem Evidence of CRH Neuron Reduction in Narcolepsy Without Cataplexy With Borderline Hypocretin‐1 Levels

Journal of Sleep Research, EarlyView.
ABSTRACT Narcolepsy is classified as type 1 (NT1) or type 2 (NT2) mainly according to hypocretin deficiency rather than cataplexy. While CRH neuron loss in the PVN has been described in NT1, it remains unclear whether similar changes occur in narcolepsy without cataplexy.
Ling Shan, Suzan Linssen, Rolf Fronczek, Lucie Barateau, Christelle Peyron, Yves Dauvilliers   +5 more
wiley   +1 more source

Risk of Hypertension and Mortality Among People With Narcolepsy or Idiopathic Hypersomnia: A Retrospective Cohort Analysis of the Danish National Patient Registry

Journal of Sleep Research, EarlyView.
This retrospective cohort study using data from the Danish National Patient Registry shows that individuals with narcolepsy or idiopathic hypersomnia have greater prevalence and risk of incident hypertension compared with matched controls, highlighting the elevated cardiovascular risk associated with these conditions.
Poul Jørgen Jennum, Michael Ibsen, Sam Mettam, Sarah C. Markt, Douglas S. Fuller, Jessica K. Alexander, Rikke Ibsen, Jakob Kjellberg, Caroleen Drachenberg   +8 more
wiley   +1 more source

Differences in Sleep Spindle Characteristics Between Children With Narcolepsy and Those With Other Causes of Subjective Sleepiness

Journal of Sleep Research, EarlyView.
ABSTRACT Central disorders of hypersomnolence are characterised by excessive daytime sleepiness. There has been growing interest in analysing sleep micro‐architecture, to further understand how sleep is affected by these conditions. We investigated if sleep spindle activity differed between children with narcolepsy, idiopathic hypersomnolence (IH) and ...
Marisha Shetty, Nushrika Kadam Kishore, Georgina Plunkett, Lauren C. Nisbet, Margot J. Davey, Gillian M. Nixon, Lisa M. Walter, Rosemary S. C. Horne   +7 more
wiley   +1 more source

Temporal patterns of sleep latency in central hypersomnia and attention deficit hyperactivity disorder: a cluster analysis exploration using Multiple Sleep Latency Test

Frontiers in Psychiatry
IntroductionExcessive daytime sleepiness (EDS) is a crucial symptom that diminishes the quality of life. The primary causes of EDS are central hypersomnia, including narcolepsy type 1 (NT1), type 2 (NT2), and idiopathic hypersomnia (IH).
Takashi Maruo, Takashi Maruo, Shunsuke Takagi, Shunsuke Takagi, Shunsuke Takagi, Sunao Uchida, Sunao Uchida, Sunao Uchida, Sunao Uchida, Hidehiko Takahashi, Hidehiko Takahashi, Genichi Sugihara   +11 more
doaj   +1 more source

Network Analysis in Central Disorders of Hypersomnolence: Insight Into Relationships Between Symptoms, Mental Health, and Quality of Life

Journal of Sleep Research, EarlyView.
Network Analysis in Central Disorders of Hypersomnolence: Insight Into Relationships Between Symptoms, Mental Health, and Quality of Life. ABSTRACT In the central disorders of hypersomnolence (CDH) narcolepsy types 1 and 2 (NT1, NT2) and idiopathic hypersomnia (IH), mental health problems are highly prevalent, and quality of life is decreased.
Denise Bijlenga, Tessa F. Blanken, Josephine J. de Boer, Rolf Fronczek, Gert Jan Lammers   +4 more
wiley   +1 more source

Impaired Alertness Correlates With Chronic Anxiety: A Prospective Tertiary University Centre Cohort

Journal of Sleep Research, EarlyView.
ABSTRACT The Maintenance of Wakefulness Test (MWT) is a widely used objective measure of daytime alertness, especially in patients with sleep disorders at increased risk of accidents. Anxiety and depression are common in this population and may influence subjective sleepiness and objective alertness.
Anice Borjon, Lucie Bobin, François Ricordeau, Lucas Marces, Hugo Fornelli, Thierry Petitjean, Amandine Viccica, Elena Charbonnier, Emeric Stauffer, Barbara Charbotel, Jacques Taillard, Renaud Tamisier, Laure Peter‐Derex, Pierre Tankéré   +13 more
wiley   +1 more source

Excessive Daytime Sleepiness and Injury of the Ascending Reticular Activating System Following Whiplash Injury

Frontiers in Neuroscience, 2018
Objectives: This study investigated injuries of the ascending reticular activating system (ARAS) following whiplash injury, in patients with excessive daytime sleepiness (EDS).Methods: Twenty-three patients with whiplash injury and 26 healthy control ...
Sung H. Jang, Seong H. Kim, Young H. Kwon   +2 more
doaj   +1 more source

Targeting Orexin 2 Receptors in Idiopathic Hypersomnia and Narcolepsy: A Randomised Phase 1b Proof‐Of‐Concept Study of Alixorexton

Journal of Sleep Research, EarlyView.
Orexin 2 receptor agonists have demonstrated that targeting the orexin system may address symptoms of central disorders of hypersomnolence. Results of this phase 1 study support the phase 2 clinical evaluation of oral alixorexton in patients with IH, NT2 and NT1.
Ronald R. Grunstein, Brendon J. Yee, Julia L. Chapman, Jian Eu Tai, Sheila Sivam, Craig Hopkinson, Daniel G. Smith, Alexandra Lovett, Shifang Liu, Sergey Yagoda, Bhaskar Rege   +10 more
wiley   +1 more source

Comparison of Actigraphy and Polysomnography in a Sleep Centre Cohort

Journal of Sleep Research, EarlyView.
MotionWatch 8 actigraphy correlated most strongly with PSG for total sleep time and showed modest group‐level bias, but wide individual limits of agreement precluded interchangeability. PLMS modified actigraphy‐PSG differences, while recording setting influenced actigraphy‐derived sleep continuity across home and inpatient recordings.
Panagis Drakatos, Iain Duncan, Laura Pérez‐Carbonell, Abidemi I. Otaiku, Fotis Kapsimalis, Sean Higgins, Meir H. Kryger, Adrian J. Williams, Guy D. Leschziner   +8 more
wiley   +1 more source