Results 1 to 10 of about 11,369 (209)

Liver stiffness assessed by real-time two-dimensional shear wave elastography predicts hypersplenism in patients with Wilson’s disease: a prospective study

BMC Medical Imaging, 2022
Background The current study aimed to explore the value of liver stiffness assessed by two-dimensional real-time shear wave elastography (2D-SWE) to predict hypersplenism occurrence in Wilson’s disease (WD) patients.
Jiajia Wang, Minxia Hu, Qiang Zhu, Lanting Sun   +3 more
doaj   +2 more sources

Efficacy and safety of laparoscopic splenectomy for hypersplenism secondary to portal hypertension after transjugular intrahepatic portosystemic shunt

BMC Gastroenterology, 2021
Background Laparoscopic splenectomy (LS) being used after Transjugular intrahepatic portosystemic shunt (TIPS) has not been reported. This report aims to explore the feasibility, safety, and potential efficacy of LS after TIPS hypersplenism secondary to ...
Yingying Li, Zuojin Liu, Chang’an Liu
doaj   +2 more sources

The protective effect of the spleen in sickle cell patients. A comparative study between patients with asplenia/hyposplenism and hypersplenism

Frontiers in Physiology, 2022
Sickle cell disease (SCD) is caused by a point mutation in the beta-globin gene. SCD is characterized by chronic hemolytic anemia, vaso-occlusive events leading to tissue ischemia, and progressive organ failure.
Sari Peretz, Sari Peretz, Leonid Livshits, Leonid Livshits, Etheresia Pretorius, Asya Makhro, Anna Bogdanova, Anna Bogdanova, Max Gassmann, Ariel Koren, Carina Levin, Carina Levin   +11 more
doaj   +2 more sources

Thalidomide for the Treatment of Thrombocytopenia and Hypersplenism in Patients With Cirrhosis or Thalassemia

Frontiers in Pharmacology, 2020
Hypersplenism and thrombocytopenia are common complications of liver cirrhosis or thalassemia, but current treatment strategies are limited. This study aimed to evaluate the efficacy and safety of thalidomide in the treatment of hypersplenism and ...
Yaocheng Chen, Ning Cai, Yongrong Lai, Weiwei Xu, Jinyan Li, Lan Huang, Ying Huang, Meiling Hu, Huangju Yang, Jiangming Chen   +9 more
doaj   +2 more sources

Successful Treatment of Hypersplenism in Wilson's Disease by Partial Splenic Embolization

Journal of Investigative Surgery, 2018
Aim: Hypersplenism can occur in patients with Wilson's disease (WD). Surgical splenectomy is a conventional treatment for this condition; however, emotional and neurological deterioration may follow splenectomy.
Liang-Yong Li, Huai-Zhen Chen, Yuan-Cheng Bao, Qing-Sheng Yu, Wen-Ming Yang   +4 more
doaj   +2 more sources

Effects of hypersplenism on the outcome of hepatectomy in hepatocellular carcinoma with hepatitis B virus related portal hypertension

Frontiers in Surgery, 2023
BackgroundAlthough hepatectomy plus splenectomy is not regularly recommended for hepatocellular carcinoma (HCC) with portal hypertension related hypersplenism due to the high risk accompanied with surgical procedures for now.
Xiao Chen, Dong Wang, Rui Dong, Tao Yang, Bo Huang, Yanlong Cao, Jianguo Lu, Jikai Yin   +7 more
doaj   +1 more source

Sorafenib plus partial splenic embolism for treatment of hepatocellular carcinoma Barcelona stage C combined with hypersplenism: a case series

Journal of International Medical Research, 2021
Background Sorafenib is mainly used to treat patients with hepatocellular carcinoma (HCC) Barcelona Clinic Liver Cancer (BCLC) stage C, many of whom also have severe cirrhosis.
Jianting Zeng, Chunmei Wang, Yu Wang, Zhenhua Luo, Yanlin Zhang, Xianzhang Luo   +5 more
doaj   +1 more source

An Uncommon Display of the Sickle Cell Trait Coupled with the Beta-Thalassemia Trait as Hypersplenism

Journal of Integrated Health Sciences, 2023
A structural flaw in the globin gene causes hemoglobinopathies, while a flaw in the globin chain’s synthesis causes thalassemia. One of the most prevalent hemoglobinopathies worldwide is sickle cell disease.
Divyesh Patel, Vedangi Desai, Palak Doshi, Shubham R. Darda, Jitendra D. Lakhani   +4 more
doaj   +1 more source

Laparoscopic Splenectomy in Colorectal Cancer Patients with Chemotherapy-Associated Thrombocytopenia due to Hypersplenism

Case Reports in Oncology, 2012
Background: Hypersplenism due to chemotherapy-related liver injury has been associated with severe thrombocytopenia that may preclude continuation of systemic therapy for cancer patients. Patients treated for metastatic colorectal cancer (mCRC) are among
David A. Litvak, Salman Malad, Robert A. Wascher, Maurie Markman, Jiaxin Niu   +4 more
doaj   +1 more source

Splenectomy in Sickle Cell Haemoglobinopathies from a Tertiary Hospital of Southern Odisha: A Retrospective Study [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Sickle Cell Disease (SCD) is a common haemoglobinopathy, where spleen is considered to be the first organ to be involved. Although it initially undergoes enlargement, but most often there occurs autosplenectomy. But in some cases, there
Abinash Kumar Panda, Bhupati Bhusan Das, B Swagat Kumar Subudhi, Indrajeet Padhy   +3 more
doaj   +1 more source