Results 1 to 10 of about 8,171 (214)

Liver stiffness assessed by real-time two-dimensional shear wave elastography predicts hypersplenism in patients with Wilson’s disease: a prospective study [PDF]

BMC Medical Imaging, 2022
Background The current study aimed to explore the value of liver stiffness assessed by two-dimensional real-time shear wave elastography (2D-SWE) to predict hypersplenism occurrence in Wilson’s disease (WD) patients.
Jiajia Wang, Minxia Hu, Qiang Zhu, Lanting Sun   +3 more
doaj   +2 more sources

The protective effect of the spleen in sickle cell patients. A comparative study between patients with asplenia/hyposplenism and hypersplenism [PDF]

Frontiers in Physiology, 2022
Sickle cell disease (SCD) is caused by a point mutation in the beta-globin gene. SCD is characterized by chronic hemolytic anemia, vaso-occlusive events leading to tissue ischemia, and progressive organ failure.
Sari Peretz, Sari Peretz, Leonid Livshits, Leonid Livshits, Etheresia Pretorius, Asya Makhro, Anna Bogdanova, Anna Bogdanova, Max Gassmann, Ariel Koren, Carina Levin, Carina Levin   +11 more
doaj   +2 more sources

Simultaneous CSM‐TACE with CalliSpheres® and partial splenic embolization using 8spheres® for hepatocellular carcinoma with hypersplenism: Early prospective multicenter clinical outcome [PDF]

Frontiers in Oncology, 2022
BackgroundPrimary hepatocellular carcinoma is often complicated with hepatitis and liver cirrhosis. Some patients develop different degrees of splenomegaly, hypersplenism and hypohepatia due to the aggravation of liver cirrhosis, which to some extent ...
Jun Zhou, Jun Zhou, Zhuo Feng, Song Liu, Xiang Li, Ying Liu, Fei Gao, Jing Shen, Yue Wei Zhang, Guang Sheng Zhao, Ming Zhang   +10 more
doaj   +2 more sources

Sorafenib plus partial splenic embolism for treatment of hepatocellular carcinoma Barcelona stage C combined with hypersplenism: a case series

Journal of International Medical Research, 2021
Background Sorafenib is mainly used to treat patients with hepatocellular carcinoma (HCC) Barcelona Clinic Liver Cancer (BCLC) stage C, many of whom also have severe cirrhosis.
Jianting Zeng, Chunmei Wang, Yu Wang, Zhenhua Luo, Yanlin Zhang, Xianzhang Luo   +5 more
doaj   +2 more sources

Diagnosis of hypersplenism with the epinephrine stimulation test

Swiss Medical Weekly, 2012
PRINCIPLES: Hypersplenism can be defined by thrombocytopenia and/or neutropenia resulting from blood cell sequestration in an enlarged spleen. In multimorbid patients the differential diagnosis of cytopenia is challenging and currently there is no ...
B Misselwitz, EB Bachli, P Kaiser, JS Goede   +3 more
doaj   +3 more sources

Effects of hypersplenism on the outcome of hepatectomy in hepatocellular carcinoma with hepatitis B virus related portal hypertension

Frontiers in Surgery, 2023
BackgroundAlthough hepatectomy plus splenectomy is not regularly recommended for hepatocellular carcinoma (HCC) with portal hypertension related hypersplenism due to the high risk accompanied with surgical procedures for now.
Xiao Chen, Dong Wang, Rui Dong, Tao Yang, Bo Huang, Yanlong Cao, Jianguo Lu, Jikai Yin   +7 more
doaj   +1 more source

Efficacy and safety of laparoscopic splenectomy for hypersplenism secondary to portal hypertension after transjugular intrahepatic portosystemic shunt

BMC Gastroenterology, 2021
Background Laparoscopic splenectomy (LS) being used after Transjugular intrahepatic portosystemic shunt (TIPS) has not been reported. This report aims to explore the feasibility, safety, and potential efficacy of LS after TIPS hypersplenism secondary to ...
Yingying Li, Zuojin Liu, Chang’an Liu
doaj   +1 more source

Laparoscopic Splenectomy in Colorectal Cancer Patients with Chemotherapy-Associated Thrombocytopenia due to Hypersplenism

Case Reports in Oncology, 2012
Background: Hypersplenism due to chemotherapy-related liver injury has been associated with severe thrombocytopenia that may preclude continuation of systemic therapy for cancer patients. Patients treated for metastatic colorectal cancer (mCRC) are among
David A. Litvak, Salman Malad, Robert A. Wascher, Maurie Markman, Jiaxin Niu   +4 more
doaj   +1 more source

An Uncommon Display of the Sickle Cell Trait Coupled with the Beta-Thalassemia Trait as Hypersplenism

Journal of Integrated Health Sciences, 2023
A structural flaw in the globin gene causes hemoglobinopathies, while a flaw in the globin chain’s synthesis causes thalassemia. One of the most prevalent hemoglobinopathies worldwide is sickle cell disease.
Divyesh Patel, Vedangi Desai, Palak Doshi, Shubham R. Darda, Jitendra D. Lakhani   +4 more
doaj   +1 more source

Thalidomide for the Treatment of Thrombocytopenia and Hypersplenism in Patients With Cirrhosis or Thalassemia

Frontiers in Pharmacology, 2020
Hypersplenism and thrombocytopenia are common complications of liver cirrhosis or thalassemia, but current treatment strategies are limited. This study aimed to evaluate the efficacy and safety of thalidomide in the treatment of hypersplenism and ...
Yaocheng Chen, Ning Cai, Yongrong Lai, Weiwei Xu, Jinyan Li, Lan Huang, Ying Huang, Meiling Hu, Huangju Yang, Jiangming Chen   +9 more
doaj   +1 more source