Results 11 to 20 of about 11,369 (209)

Clinical observation and risk assessment after splenectomy in hepatolenticular degeneration patients associated with hypersplenism

Frontiers in Surgery, 2022
BackgroundBoth hepatolenticular degeneration (HLD) and viral hepatitis B (HBV) can cause hypersplenism, but whether splenectomy is needed or can be performed in HLD patients associated with hypersplenism is still controversial.
Wanzong Zhang, Wanzong Zhang, Qingsheng Yu, Qingsheng Yu, Hui Peng, Hui Peng, Zhou Zheng, Zhou Zheng, Fuhai Zhou, Fuhai Zhou   +9 more
doaj   +2 more sources

Eighty percent partial splenic embolization is a safe and effective procedure in management of cirrhotic hypersplenism

Formosan Journal of Surgery, 2017
Background: Partial splenic embolization (PSE) has been proposed in patients with cirrhotic hypersplenism in cases when thrombocytopenia causes clinical manifestations or if there are contraindications to subsequent therapeutic procedures.
Bor-Gang Wu, Andy Shau-Bin Chou, Guan-Jin Ho, Ming-Che Lee   +3 more
doaj   +2 more sources

Long-Term Outcomes of Extrahepatic Portal Vein Obstruction-A Nationwide Registry-Based Follow-Up Study From 1987 to 2023. [PDF]

Liver Int
ABSTRACT Background and Aims Extrahepatic portal vein obstruction (EHPVO) is among the main causes of childhood portal hypertension. We analysed nationwide long‐term outcomes of EHPVO in relation to various management options. Methods In total, 62 consecutive patients with EHPVO diagnosed between 1987 and 2023 were followed up through hospital records ...
Luoto T, Hukkinen M, Pakarinen MP.
europepmc   +2 more sources

Baseline ALBI Grade Predicts Benefits After Splenectomy for Cirrhotic Patients with Hypersplenism

Journal of Gastrointestinal Surgery, 2023
Splenectomy is an effective treatment for correcting cytopenia caused by hypersplenism secondary to cirrhosis. However, other potential benefits have not been well characterized.
Qi Zhu, De-sheng Chen, Yichao Lou, Xueqian Xie, Yi Wu, Zhaowen Wang, Hongcheng Sun   +6 more
semanticscholar   +1 more source

Effect of splenectomy based on inverse probability weighting of the propensity score on Wilson's disease with hypersplenism: A retrospective cohort study

Experimental and Therapeutic Medicine, 2023
Hypersplenism is a long-term complication of Wilson's disease (WD). Patients often have to stop copper excretion treatment due to the decrease in blood cell count aggravation of abnormal liver function, anaemia, bleeding caused by coagulation dysfunction.
Hong Chen, Xie-Kui Wang, Juan Zhang, Dao-Jun Xie   +3 more
semanticscholar   +1 more source

Repeated partial splenic artery embolization for hypersplenism improves platelet count

Open Medicine, 2022
Splenic embolization is a minimally invasive alternative to splenectomy for the treatment of hypersplenism. This was a retrospective study of 101 patients with hypersplenism caused by cirrhosis who were treated with splenic embolization and for whom 6 ...
Youwen Tan, Jia-Min Wang, Li Sun, Yun Ye
semanticscholar   +1 more source

Partial splenic embolization combined with endoscopic therapies and NSBB decreases the variceal rebleeding rate in cirrhosis patients with hypersplenism: a multicenter randomized controlled trial

Hepatology International, 2021
Global research on endoscopic therapies in combination with partial splenic embolization (PSE) for variceal hemorrhage (VH) is limited. Therefore, we aimed to evaluate the efficacy and safety of endoscopy plus PSE (EP) treatment in comparison to ...
Xin Sun, Anzhong Zhang, Tao Zhou, Minghui Wang, Yong Chen, Ting Zhou, Xiaoning Chen, Aiyuan Xiu, Zhi Peng, Bao-quan Cheng, Xiaofeng Liu, Yan-jing Gao   +11 more
semanticscholar   +1 more source

Comparison of three embolic materials at partial splenic artery embolization for hypersplenism: clinical, laboratory, and radiological outcomes

Insights into Imaging, 2021
Purpose To compare effectiveness of three widely used embolic agents in partial splenic embolization (PSE) by analyzing their clinical, laboratory, and radiological outcomes within one year of follow-up.
Mohamed M. A. Zaitoun, M. Basha, S. Elsayed, Dalia Salah El Deen, N. Zaitoun, Husain Alturkistani, Alaa A Farag, H. Abdelsalam, Hossam A. El-Kenawy, Nader E. M. Mahmoud, N. Alayouty, Ibrahim M Eladl, Shahenda Shahin, M. Almarzooqi, A. Hendi, Ahmad El-Morsy, A. Elmokadem   +16 more
semanticscholar   +1 more source

CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis

Hepatology, EarlyView., 2022
A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang, Dan Wan, Mengchen Zhu, Guihu Wang, Xurui Zhang, Na Huang, Jian Zhang, Chongyu Zhang, Qi Shang, Chen Zhang, Xi Liu, Fanfan Liang, Chunyan Zhang, Guangyao Kong, Jing Geng, Libo Yao, Shemin Lu, Yongyan Chen, Zongfang Li   +18 more
wiley   +1 more source

Covered Transjugular Intrahepatic Portosystemic Shunt Improves Hypersplenism-Associated Cytopenia in Cirrhosis

Zeitschrift für Gastroenterologie - German Journal of Gastroenterology, 2021
Patients with cirrhosis often develop portal hypertension-associated splenomegaly and hypersplenism, potentially causing severe cytopenia. Systematic assessment on the impact of transjugular intrahepatic portosystemic shunt (TIPS) implantation on ...
T. Bucsics, K. Lampichler, Constantin Vierziger, M. Schoder, F. Wolf, D. Bauer, B. Simbrunner, L. Hartl, M. Jachs, B. Scheiner, M. Trauner, T. Gruenberger, F. Karnel, M. Mandorfer, T. Reiberger   +14 more
semanticscholar   +1 more source