CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis
Hepatology, EarlyView., 2022 A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.
Shaoying Zhang +18 more
wiley +1 more source
Immune-Mediated Thrombocytopenia in an Ulcerative Colitis Patient After Initiating Filgotinib Treatment: A Case Report. [PDF]
Clin Case RepTimeline of events ABSTRACT Moderate‐to‐severe ulcerative colitis can be effectively treated with JAK‐1 inhibition, but platelet counts should be closely monitored, especially in active disease. We confirmed immune‐mediated thrombocytopenia (ITP) in one of our patients after the initiation of filgotinib. Whether this was drug‐induced is uncertain.
van der Hoff MJ +2 more
europepmc +2 more sources
Warren shunt combined with partial splenectomy in children with extra-hepatic portal hypertension, massive splenomegaly and severe hypersplenism [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2014 Introduction. Extra-hepatic portal vein obstruction (EHPVO) is one of the most often causes of portal hypertension in children. Objective. Establishing the importance of shunt surgery in combination with partial spleen resection in selected ...
Sretenović Aleksandar +6 more
doaj +1 more source
Successful Treatment of Hypersplenism in Wilson's Disease by Partial Splenic Embolization
Journal of Investigative Surgery, 2018 Aim: Hypersplenism can occur in patients with Wilson's disease (WD). Surgical splenectomy is a conventional treatment for this condition; however, emotional and neurological deterioration may follow splenectomy.
Liang-Yong Li +4 more
doaj +1 more source
Frontiers in Surgery, 2022 BackgroundBoth hepatolenticular degeneration (HLD) and viral hepatitis B (HBV) can cause hypersplenism, but whether splenectomy is needed or can be performed in HLD patients associated with hypersplenism is still controversial.
Wanzong Zhang +9 more
doaj +1 more source
Laparoscopic splenic artery ligation for hypersplenism in cirrhosis: A case series
Journal of Minimal Access Surgery, 2016 Background: Splenectomy for the treatment of hypersplenism in patients with cirrhosis (HIC) is related with complications. Laparoscopic splenic artery ligation (LSAL) may be an alternative treatment option.
Hirdaya H Nag +3 more
doaj +1 more source
Granulomatous Liver Disease in Ataxia-Telangiectasia With the Hyper-IgM Phenotype: A Case Report
Frontiers in Pediatrics, 2020 Ataxia-telangiectasia (A-T) is an autosomal recessive disorder characterized by neurodegeneration, combined immunodeficiency, and oculocutaneous telangiectasia. The hyper-IgM phenotype of A-T, correlating with a class-switch recombination defect, IgG and
Aleksandra Szczawińska-Popłonyk +2 more
doaj +1 more source
Distal splenorenal shunt with partial spleen resection [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2007 Introduction: Hypersplenism is a common complication of portal hypertension. Cytopenia in hypersplenism is predominantly caused by splenomegaly. Distal splenorenal shunt (Warren) with partial spleen resection is an original surgical technique that ...
Gajin Predrag +5 more
doaj +1 more source
Splenectomy in Sickle Cell Haemoglobinopathies from a Tertiary Hospital of Southern Odisha: A Retrospective Study [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: Sickle Cell Disease (SCD) is a common haemoglobinopathy, where spleen is considered to be the first organ to be involved. Although it initially undergoes enlargement, but most often there occurs autosplenectomy. But in some cases, there
Abinash Kumar Panda +3 more
doaj +1 more source
La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 2003 J, LEBON +2 more
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