Results 71 to 80 of about 11,369 (209)

Hepatopulmonary syndrome in children and adolescents with portal hypertension in Brazil: A multicenter study

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 2, Page 366-373, February 2026.
Abstract Objectives To describe the clinical and laboratory characteristics and outcomes of pediatric hepatopulmonary syndrome (HPS) secondary to portal hypertension (PH) in Brazil. Methods Fifty‐four pediatric patients diagnosed with PH and HPS according to the European Respiratory Society criteria were included in this multicenter retrospective study.
Leticia Drumond Alberto, Eleonora Druve Tavares Fagundes, Adriana Teixeira Rodrigues, Thaís Costa Nascentes Queiroz, Gustavo Valverde de Castro, Carlos Oscar Kieling, Sandra Maria Gonçalves Vieira, Natália Lamounier dos Martires Guerra, Natascha Silva Sandy, Gilda Porta, Irene Kazue Miura, Maria Ângela Bellomo Brandão, Gabriel Hessel, Adriana Maria Alves de Tommaso, Alexandre Rodrigues Ferreira   +14 more
wiley   +1 more source

"Splenism" - the function of spleen, as the organ conducting the interrelation of the circulatory system and hematopoiesis

Patologìâ, 2013
On Wistar rats splenic involvement into the regulation of erythropoiesis was studied. Splenomegaly was reproduced for this both by ligation of splenic veins and transfusion of suspension of washed erythrocytes that leaded to the pronounced increase in ...
V.I. Filimonov, N.V. Stepanova, I.E. Sukhomlinova, M.A. Tikhonovskaya, G.I. Bessarab, D.A. Putilin, G.V. Pirtya   +6 more
doaj   +1 more source

Romiplostim therapy as a second‐line treatment before splenectomy for refractory immune thrombocytopenia in a cirrhotic patient with iatrogenic Cushing syndrome secondary to corticosteroids

Clinical Case Reports, 2017
Key Clinical Message Our case report discusses the usefulness of administering romiplostim as a second‐line treatment before splenectomy in a cirrhotic patient with immune thrombocytopenia who developed corticosteroid‐induced Cushing's syndrome ...
Teresa Casanovas Taltavull, Maria Carmen Peña‐Cala   +1 more
doaj   +1 more source

SUCCESSFUL CHEMOTHERAPY ADMINISTRATION DESPITE HYPERSPLENISM AND PANCYTOPENIA: A CASE OF METASTATIC RECTAL ADENOCARCINOMA

Hematology, Transfusion and Cell Therapy
Introduction: Cytopenias in oncology patients present a significant barrier to the administration of chemotherapy. Hypersplenism is one of the leading causes of cytopenia.
Adil Uğur Kaan Güngör, Abdurrahman Aykut, Berksoy Sahin, Hatice Asoğlu Rüzgar   +3 more
doaj   +1 more source

Portal hypertension: A critical appraisal of shunt procedures with emphasis on distal splenorenal shunt in children

Journal of Indian Association of Pediatric Surgeons, 2014
Background: Extrahepatic portal venous obstruction (EHPVO) is the most common cause of pediatric portal hypertension. We analyzed the investigative protocol and results of portosystemic shunts in this group of patients.
Nitin Sharma, Minu Bajpai, Arbinder Kumar, Shashi Paul, Manisha Jana   +4 more
doaj   +1 more source

Risk Factors for Postoperative Complications After Splenectomy in Wilson’s Disease: A 986-Patient Single-Center Cohort Study

Journal of Investigative Surgery
Introduction Splenectomy is commonly performed in Wilson’s disease patients with hypersplenism secondary to portal hypertension, yet large-scale data on postoperative complications remain scarce.Methods A retrospective analysis was conducted on 986 ...
Xiuquan Shi, Sihuan Zhu, Hui Peng, Lei Jin, Qingsheng Yu   +4 more
doaj   +1 more source

Diagnosis of hypersplenism with the epinephrine stimulation test

Swiss Medical Weekly, 2012
PRINCIPLES: Hypersplenism can be defined by thrombocytopenia and/or neutropenia resulting from blood cell sequestration in an enlarged spleen. In multimorbid patients the differential diagnosis of cytopenia is challenging and currently there is no ...
B Misselwitz, EB Bachli, P Kaiser, JS Goede   +3 more
doaj   +1 more source

Splenic Arterial Embolization for Trauma and Beyond: A Case Series

Vascular Specialist International
Splenic artery embolization plays an important role in the management of various medical and surgical conditions that are non-traumatic in etiology, in addition to its well-established and widely discussed role in managing splenic trauma. In nontraumatic
Chun Hin Choy, Yat Sing Lee, Pui Lam Cheung, Cheuk Him Ho, Jimmy Chi Wai Siu   +4 more
doaj   +1 more source

Activation of MEK‐ERK‐c‐MYC signaling pathway promotes splenic M2-like macrophage polarization to inhibit PHcH-liver cirrhosis

Frontiers in Immunology
IntroductionPortal hypertension combined with hypersplenism (PHcH) is the main cause of hypocytosis and esophagogastric variceal hemorrhage in patients with liver cirrhosis.
Wang Guihu, Wang Guihu, Dong Wei, Dong Wei, Zhang Hailong, Zhang Hailong, Zhang Chongyu, Zhang Chongyu, Sun Jin, Sun Jin, Zhu Mengchen, Zhu Mengchen, Zhang Jian, Zhang Jian, Zhou Rui, Zhou Rui, Ren Song, Ren Song, Zhang Chen, Zhang Chen, Liu Xi, Liu Xi, Li Zongfang, Li Zongfang, Jiang An, Jiang An, Jiang An   +26 more
doaj   +1 more source

Extracellular Vesicle Characteristics in β-thalassemia as Potential Biomarkers for Spleen Functional Status and Ineffective Erythropoiesis

Frontiers in Physiology, 2018
β-thalassemia major (β-TM) is a therapeutically challenging chronic disease in which ineffective erythropoiesis is a main pathophysiological factor. Extracellular vesicles (EVs) are membrane-enclosed vesicles released by cells into biological fluids ...
Carina Levin, Carina Levin, Ariel Koren, Ariel Koren, Annie Rebibo-Sabbah, Naama Koifman, Benjamin Brenner, Benjamin Brenner, Anat Aharon, Anat Aharon   +9 more
doaj   +1 more source