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Inducing TRIB2 Targeted Protein Degradation to Reverse Chemoresistance in Acute Myeloid Leukaemia

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Hyperstate Space Graphs

IEEE Transactions on Games, 2022
Automatically analyzing games is an important challenge for automated game design, general game playing, and cocreative game design tools. However, understanding the nature of an unseen game is extremely difficult due to the lack of a priori design knowledge and heuristics. In this article, we formally define hyperstate space graphs , a compressed form
Michael Cook, Azalea Raad
openaire   +2 more sources

Engineering ancestral protein hyperstability

Biochemical Journal, 2016
Many experimental analyses and proposed scenarios support that ancient life was thermophilic. In congruence with this hypothesis, proteins encoded by reconstructed sequences corresponding to ancient phylogenetic nodes often display very high stability.
M Luisa, Romero-Romero   +4 more
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Aza-Glycine Induces Collagen Hyperstability

Journal of the American Chemical Society, 2015
Hydrogen bonding is fundamental to life on our planet, and nature utilizes H-bonding in nearly all biomolecular interactions. Often, H-bonding is already maximized in natural biopolymer systems such as nucleic acids, where Watson-Crick H-bonds are fully paired in double-helical structures.
Yitao, Zhang   +2 more
openaire   +2 more sources

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