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Hypertension [PDF]

open access: yesAmerican Journal of Kidney Diseases, 2004
Hypertension is a rapidly moving clinical field with frequent developments in new pharmacologic agents and management strategies. Perhaps more importantly, there have been substantial improvements in our understanding of how best to use the drugs ...
Farrugia, Emanuel
core   +3 more sources

Hypertension [PDF]

open access: yesNature Reviews Disease Primers, 2018
Systemic arterial hypertension is the most important modifiable risk factor for all-cause morbidity and mortality worldwide and is associated with an increased risk of cardiovascular disease (CVD). Fewer than half of those with hypertension are aware of their condition, and many others are aware but not treated or inadequately treated, although ...
Oparil, Suzanne   +10 more
  +12 more sources

Hypertension [PDF]

open access: yesGlobal Advances in Health and Medicine, 2012
Hypertension is responsible for roughly one-in-six adult deaths annually in the United States and is associated with five of the top nine causes of death.1 Ten trillion dollars is the estimated annual cost worldwide of the direct and indirect effects of hypertension.2,3 In the U.S.
Fitzgerald, Kara, LePine, Todd
  +8 more sources

Sodium‐Glucose Cotransporter 2 Inhibitor Canagliflozin Antagonizes Salt‐Sensitive Hypertension Through Modifying Transient Receptor Potential Channels 3 Mediated Vascular Calcium Handling

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Salt‐sensitive hypertension is highly prevalent and associated with cardiorenal damage. Large clinical trials have demonstrated that SGLT2 (sodium‐glucose cotransporter 2) inhibitors exert hypotensive effect and cardiorenal protective benefits
Yu Zhao   +15 more
doaj   +1 more source

Hypertension [PDF]

open access: yesCurrent Treatment Options in Cardiovascular Medicine, 1991
Controlled multicenter clinical trials and almost 50 years of clinical experience have demonstrated incontrovertibly the efficacy, safety, and feasibility of antihypertensive pharmacotherapy. In addition, this vast clinical record has shown, through the intrinsic ability of antihypertensive therapy to control arterial pressure, how to prevent and ...
G W, Ching, D G, Beevers
openaire   +4 more sources

Asprosin induces vascular endothelial-to-mesenchymal transition in diabetic lower extremity peripheral artery disease

open access: yesCardiovascular Diabetology, 2022
Background Altered adipokine secretion in dysfunctional adipose tissue facilitates the development of atherosclerotic diseases including lower extremity peripheral artery disease (PAD).
Mei You   +12 more
doaj   +1 more source

Poor sleep quality is negatively associated with low cognitive performance in general population independent of self-reported sleep disordered breathing

open access: yesBMC Public Health, 2022
Background Sleep disordered breathing (SDB) plays a significant role in both sleep quality and cognition and whether it has an impact on the relationship between above two factors remains to be clear.
Zhongrong Wang   +12 more
doaj   +1 more source

Korea hypertension fact sheet 2018

open access: yesClinical Hypertension, 2018
Background The Korea Hypertension Fact Sheet 2018 aims to overview the magnitude and management status of hypertension, and their trends in Korea. Methods The Hypertension Epidemiology Research Group analyzed the 1998–2016 Korea National Health and ...
The Korean Society Hypertension (KSH)   +3 more
doaj   +1 more source

Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms [PDF]

open access: yes, 2018
Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as frequent in patients with diabetes compared with those who do not have diabetes.
Guzik, Tomasz J.   +2 more
core   +1 more source

Clinical Characteristics of Target Organ Damage in Primary Aldosteronism with or without Metabolic Syndrome

open access: yesJournal of Diabetes Research, 2022
The aim of this study is to investigate the prevalence of metabolic disorders in patients with primary aldosteronism (PA) and target organ damage (TOD) in different subtypes of patients with PA with or without metabolic syndrome (MS).
Xiaona Bu   +8 more
doaj   +1 more source

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