Results 41 to 50 of about 2,904,733 (344)

Association between eNOS rs1799983 polymorphism and hypertension: a meta-analysis involving 14,185 cases and 13,407 controls

BMC Cardiovascular Disorders, 2021
Background Essential hypertension is a complex disease determined by the interaction of genetic and environmental factors, eNOS is considered to be one of the susceptible genes for hypertension.
Jikang Shi, Si-Yu Liu, Yanbo Guo, Sai-Nan Liu, Jiayi Xu, Lingfeng Pan, Yueyang Hu, Yawen Liu, Yi Cheng   +8 more
semanticscholar   +1 more source

Assessment of sublingual microcirculation for the screening of diabetic nephropathy

Diabetology & Metabolic Syndrome, 2022
Objective To investigate the potential of employing sublingual microcirculation as an early noninvasive screening technique for diabetic nephropathy (DN).
Qiang Li, XiaoXiao Liu, Mengxiao Jia, Fang Sun, Yingsha Li, Hexuan Zhang, Xiaoli Liu, Hongbo He, Zhigang Zhao, Zhencheng Yan, Zhiming Zhu   +10 more
doaj   +1 more source

Arterial stiffness and hypertension

Clinical Hypertension, 2023
Arterial stiffness and hypertension are closely related in pathophysiology. Chronic high blood pressure (BP) can lead to arterial wall damage by mechanical stress, endothelial dysfunction, increased inflammation, oxidative stress, and renin–angiotensin ...
Hack-Lyoung Kim
semanticscholar   +1 more source

Hypertension Pharmacological Treatment in Adults: A World Health Organization Guideline Executive Summary

HYPERTENSION, 2021
Hypertension is a major cause of cardiovascular disease and deaths worldwide especially in low- and middle-income countries. Despite the availability of safe, well-tolerated, and cost-effective blood pressure (BP)-lowering therapies,
A. Al-Makki, D. DiPette, P. Whelton, M. Murad, R. Mustafa, Shrish Acharya, H. Beheiry, B. Champagne, K. Connell, M. Cooney, N. Ezeigwe, T. Gaziano, Agaba Gidio, P. López-Jaramillo, U. Khan, V. Kumarapeli, Andrew E. Moran, Margaret Mswema Silwimba, B. Rayner, Apichard Sukonthasan, Jing Yu, Nizal Saraffzadegan, K. Reddy, Taskeen Khan   +23 more
semanticscholar   +1 more source

Higher plasma renin activity is associated with increased kidney damage risk in patients with hypertension and glucose metabolic disorders

The Journal of Clinical Hypertension, 2022
The impact of renin on kidney remain unclear among hypertensives with glucose metabolic disorders (GMD). We aimed to evaluate the association between plasma renin activity (PRA) and kidney damage in hypertensive patients with GMD.
Mengyue Lin, Mulalibieke Heizhati, Lin Gan, Jing Hong, Ting Wu, Zuhere Xiamili, Ling Tong, Yue Lin, Nanfang Li   +8 more
doaj   +1 more source

Primary aldosteronism in Klinefelter’s syndrome: two cases

Endocrinology, Diabetes & Metabolism Case Reports, 2019
Primary aldosteronism (PA) is more common than expected. Aberrant adrenal expression of luteinizing hormone (LH) receptor in patients with PA has been reported; however, its physiological role on the development of PA is still unknown.
Yasufumi Seki, Satoshi Morimoto, Naohiro Yoshida, Kanako Bokuda, Nobukazu Sasaki, Midori Yatabe, Junichi Yatabe, Daisuke Watanabe, Satoru Morita, Keisuke Hata, Tomoko Yamamoto, Yoji Nagashima, Atsuhiro Ichihara   +12 more
doaj   +1 more source

Hypertension-induced cognitive impairment: from pathophysiology to public health

Nature Reviews Nephrology, 2021
Hypertension affects two-thirds of people aged >60 years and significantly increases the risk of both vascular cognitive impairment and Alzheimer’s disease. Hypertension compromises the structural and functional integrity of the cerebral microcirculation,
Z. Ungvari, Peter Toth, S. Tarantini, C. Prodan, Farzaneh A. Sorond, B. Merkely, A. Csiszar   +6 more
semanticscholar   +1 more source

Joint UK societies' 2014 consensus statement on renal denervation for resistant hypertension. [PDF]

, 2014
Resistant hypertension continues to pose a major challenge to clinicians worldwide and has serious implications for patients who are at increased risk of cardiovascular morbidity and mortality with this diagnosis.
Matson, M, Williams, B, Paton, JF, Kapil, Vikas, Moss, J, Simpson, Iain, Knight, Charles, Poulter, Neil, Poulter, N, Collier, David, de Belder, Mark A, Caulfield, Mark J, Matson, Matthew, Simpson, I, Cleveland, Trevor, Deanfield, John, Lobo, MD, de Belder, MA, Williams, Bryan, Lobo, Melvin D, Moss, Jonathan, Caulfield, MJ, Kapil, V, Knight, C, Paton, Julian F R, Dasgupta, I, Paton, JFR, Deanfield, J, ?, ?, Cleveland, T, Collier, D, Dasgupta, Indranil   +31 more
core   +1 more source

Enhanced Mitochondrial Transient Receptor Potential Channel, Canonical Type 3–Mediated Calcium Handling in the Vasculature From Hypertensive Rats

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundMitochondrial Ca2+ homeostasis is fundamental to the regulation of mitochondrial reactive oxygen species (ROS) generation and adenosine triphosphate production.
Bin Wang, Shiqiang Xiong, Shaoyang Lin, Weijie Xia, Qiang Li, Zhigang Zhao, Xing Wei, Zongshi Lu, Xiao Wei, Peng Gao, Daoyan Liu, Zhiming Zhu   +11 more
doaj   +1 more source

Gut microbiota and hypertension: association, mechanisms and treatment

Clinical and experimental hypertension, 2023
Objectives Hypertension is one of the most important risk factors for cardio-cerebral vascular diseases, which brings a heavy economic burden to society and becomes a major public health problem.
Zhihua Yang, Qingchun Wang, Yangxi Liu, Lin Wang, Zhao Ge, Zhen-zhen Li, Shaoling Feng, Chongming Wu   +7 more
semanticscholar   +1 more source