Results 51 to 60 of about 1,396,064 (259)

Activation of Transient Receptor Potential Melastatin Subtype 8 Attenuates Cold‐Induced Hypertension Through Ameliorating Vascular Mitochondrial Dysfunction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundEnvironmental cold‐induced hypertension is common, but how to treat cold‐induced hypertension remains an obstacle. Transient receptor potential melastatin subtype 8 (TRPM8) is a mild cold‐sensing nonselective cation channel that is activated by
Shiqiang Xiong, Bin Wang, Shaoyang Lin, Hexuan Zhang, Yingsha Li, Xing Wei, Yuanting Cui, Xiao Wei, Zongshi Lu, Peng Gao, Li Li, Zhigang Zhao, Daoyan Liu, Zhiming Zhu   +13 more
doaj   +1 more source

Essential hypertension: the heart and hypertension [PDF]

Heart, 2001
The heart and hypertension are intimately linked. Hypertension predisposes to coronary heart disease, myocardial hypertrophy, and cardiac dysfunction. Other organs and systems are also important in hypertension but this article concentrates on the effect of hypertension on the heart.
K E, Berkin, S G, Ball
openaire   +2 more sources

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Leptin receptor deficiency impedes metabolic surgery related-weight loss through inhibition of energy expenditure in db/db mice

Diabetology & Metabolic Syndrome
Background Roux-en-Y gastric bypass (RYGB) surgery is an effective metabolic surgery against diabetes and obesity. Clinical evidence indicates that patients with severe obesity have a poor curative effect in losing weight if they suffer from leptin or ...
Dan Tong, Jie Xiang, Wei Liu, Fang Sun, Lijuan Wang, Aidi Mou, Tingbing Cao, Qing Zhou, Mei You, Yingying Liao, Peng Gao, Daoyan Liu, Zongshi Lu, Zhiming Zhu   +13 more
doaj   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

The body mass index-glucose index as a new tool for early detection of the risk of dysglycemia in patients with hypertension and obstructive sleep apnea

BMC Endocrine Disorders
Purpose Currently, there is a lack of early biomarkers to identify the risk of dysglycemia in patients with concurrent hypertension and obstructive sleep apnea (OSA).
Wenbo Yang, Xintian Cai, Mulalibieke Heizhati, Qing Zhu, Xiaoguang Yao, Wen Wen, Di Shen, Junli Hu, Jing Hong, Nanfang Li   +9 more
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Associated lifestyle factors of elevated plasma aldosterone concentration in community population, gender-stratified analysis of a cross-sectional survey

BMC Public Health
Background Aldosterone plays important parts in development of cardio-metabolic diseases as end product of renin-angiotensin-aldosterone system. However, factors elevating circulating aldosterone are not clear, and lifestyle-related factors are suggested
Adalaiti Maitituersun, Mulalibieke Heizhati, Nanfang Li, Lin Gan, Mei Li, Ling Yao, Wenbo Yang, Shasha Liu, Xiayire Aierken, Hui Wang, Miaomiao Liu, Jing Hong, Ting Wu, Delian Zhang, Qing Zhu   +14 more
doaj   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source