Results 71 to 80 of about 2,904,733 (344)

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Essential hypertension: the heart and hypertension [PDF]

Heart, 2001
The heart and hypertension are intimately linked. Hypertension predisposes to coronary heart disease, myocardial hypertrophy, and cardiac dysfunction. Other organs and systems are also important in hypertension but this article concentrates on the effect of hypertension on the heart.
K E, Berkin, S G, Ball
openaire   +2 more sources

European Society of Hypertension practice guidelines for ambulatory blood pressure monitoring.

, 2014
Given the increasing use of ambulatory blood pressure monitoring (ABPM) in both clinical practice and hypertension research, a group of scientists, participating in the European Society of Hypertension Working Group on blood pressure monitoring and ...
Clement, D., Fagard, R., Zanchetti, A., Parati, G., Myers, M., Waeber, B., vanMontfrans, G., Ohkubo, T., Ruilope, L.M., Imai, Y., Wang, J., Graves, J., Zhang, Y., Omboni, S., Stergiou, G., Bilo, G., Dolan, E., de Leeuw, P., Ogedegbe, G., Palatini, P., Redon, J., Staessen, J.A., Kario, K., Mancia, G., de la Sierra, A., Verdecchia, P., Mengden, T., Mallion, J.M., Head, G.A., Shennan, A., Asmar, R., Lurbe, E., Beilin, L., O'Brien, E., Cardiovascular, Variability   +34 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Pressor mechanisms in adriamycin-induced nephropathy with hypertension in rats

, 1994
We explored the role of angiotensin II and vasopressin in the maintenance of blood pressure during the nephrotic syndrome of adriamycin-induced nephropathy in rats.
Ferrari-Spadotto, A., Franco, R., Georgette, J., Gavras, I., Gavras, H., Gut, A.   +5 more
core   +2 more sources

Pheochromocytoma/Paraganglioma (PPGL): A Misdiagnosed Cause of Hypertension during Pregnancy

Case Reports in Obstetrics and Gynecology
Hypertension (HT) during pregnancy is not an infrequent obstetric problem, reaching a prevalence of 5-10%. This condition is highly associated with both maternal and fetal complications if not precisely diagnosed and managed.
Rafael Buck Giorgi, Priscila Teixeira Aroucha, Thalissa M. Favreto, Micaela F. Montero, Julia M. F. Velloni, Ilana Korkes, Elisa Napolitano Ferreira, Caroline Olivati, Jose Viana Lima, Claudio E. Kater, Flavia A. Costa-Barbosa   +10 more
doaj   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives

European Respiratory Journal, 2019
Clinical and translational research has played a major role in advancing our understanding of pulmonary hypertension (PH), including pulmonary arterial hypertension and other forms of PH with severe vascular remodelling (e.g.
M. Humbert, C. Guignabert, S. Bonnet, P. Dorfmüller, J. Klinger, M. Nicolls, A. Olschewski, S. Pullamsetti, R. Schermuly, K. Stenmark, M. Rabinovitch   +10 more
semanticscholar   +1 more source

Generalised and abdominal obesity and risk of diabetes, hypertension and hypertension–diabetes co-morbidity in England [PDF]

, 2008
Objectives To look at trends in generalised (body mass index (BMI) ≥30 kg m–2) and abdominal (waist circumference (WC) >102 cm in men, >88 cm in women) obesity among adults between 1993 and 2003, and to evaluate their association with diabetes ...
Hirani, V., Zaninotto, P., Primatesta, P.   +2 more
core  

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source