Angiotensin type-2 (AT-2)-receptor activation reduces renal fibrosis in cyclosporine nephropathy: evidence for blood-pressure independent effect [PDF]
Compound 21 (C21), selective agonist of AT2 receptors, shows antinflammatory effects in hypertension and nephroprotection in diabetes. The aim of this study was to evaluate the effects of C21 in cyclosporine nephropathy, which is characterized mainly by ...
Carletti, R+5 more
core +1 more source
Learning to Identify Patients at Risk of Uncontrolled Hypertension Using Electronic Health Records Data [PDF]
Hypertension is a major risk factor for stroke, cardiovascular disease, and end-stage renal disease, and its prevalence is expected to rise dramatically. Effective hypertension management is thus critical. A particular priority is decreasing the incidence of uncontrolled hypertension.
arxiv
Hypertension Detection From High-Dimensional Representation of Photoplethysmogram Signals [PDF]
Hypertension is commonly referred to as the "silent killer", since it can lead to severe health complications without any visible symptoms. Early detection of hypertension is crucial in preventing significant health issues. Although some studies suggest a relationship between blood pressure and certain vital signals, such as Photoplethysmogram (PPG ...
arxiv
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong+20 more
wiley +1 more source
Gut Microbiota and Cardiovascular Uremic Toxicities
Cardiovascular disease (CVD) remains a major cause of high morbidity and mortality in patients with chronic kidney disease (CKD). Numerous CVD risk factors in CKD patients have been described, but these do not fully explain the high pervasiveness of CVD ...
Manuel T. Velasquez+4 more
doaj +1 more source
The effect of rural-to-urban migration on renal function in an Indian population: cross-sectional data from the Hyderabad arm of the Indian Migration Study. [PDF]
BACKGROUND: Urban migration is associated with an increased risk of hypertension, obesity and diabetes in Indian migrants. This study assessed the relationship between internal migration and renal function in the Hyderabad arm of the Indian Migration ...
Bailey, Phillippa K+7 more
core +2 more sources
Core determinants of quality criteria for mhealth for hypertension: evidence from machine learning instruments [PDF]
Uncontrolled hypertension is a global problem that needs to be addressed. Despite the many mHealth solutions in the market, the nonadherence relative to intended use jeopardizes treatment success. Although investigating user experience is one of the most important mechanisms for understanding mHealth discontinuance, surprisingly, the core determinants ...
arxiv
In people with overweight or obesity, regular exercise even without weight loss or vitamin D supplementation completely prevents the usual winter decline in the vitamin D metabolite that maintains health at a cellular level, 1,25(OH)2D3, and ameliorates the decline in the vitamin D status marker 25(OH)D.
Oliver J. Perkin+11 more
wiley +1 more source
Nephrotic syndrome in very elderly: Should we treat aggressively?
Chronic kidney disease and acute kidney injury are being increasingly recognized in very elderly patients, aged 80 or more. In cases of suspected glomerulonephritis with or without nephrotic syndrome, the clinical decision-making of whether to obtain a ...
Abhilash Koratala, Jogiraju Tantravahi
doaj +1 more source
We addressed if oxidative stress in the renal cortex plays a role in the induction of hypertension and mitochondrial alterations in hyperuricemia. A second objective was to evaluate whether the long-term treatment with the antioxidant Tempol prevents ...
Magdalena Cristóbal-García+11 more
semanticscholar +1 more source