Results 91 to 100 of about 2,534,413 (315)

Angiotensin type-2 (AT-2)-receptor activation reduces renal fibrosis in cyclosporine nephropathy: evidence for blood-pressure independent effect [PDF]

open access: yes, 2016
Compound 21 (C21), selective agonist of AT2 receptors, shows antinflammatory effects in hypertension and nephroprotection in diabetes. The aim of this study was to evaluate the effects of C21 in cyclosporine nephropathy, which is characterized mainly by ...
Carletti, R   +5 more
core   +1 more source

Learning to Identify Patients at Risk of Uncontrolled Hypertension Using Electronic Health Records Data [PDF]

open access: yesarXiv, 2019
Hypertension is a major risk factor for stroke, cardiovascular disease, and end-stage renal disease, and its prevalence is expected to rise dramatically. Effective hypertension management is thus critical. A particular priority is decreasing the incidence of uncontrolled hypertension.
arxiv  

Hypertension Detection From High-Dimensional Representation of Photoplethysmogram Signals [PDF]

open access: yesarXiv, 2023
Hypertension is commonly referred to as the "silent killer", since it can lead to severe health complications without any visible symptoms. Early detection of hypertension is crucial in preventing significant health issues. Although some studies suggest a relationship between blood pressure and certain vital signals, such as Photoplethysmogram (PPG ...
arxiv  

Integrative Multi‐Omics and Routine Blood Analysis Using Deep Learning: Cost‐Effective Early Prediction of Chronic Disease Risks

open access: yesAdvanced Science, EarlyView.
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong   +20 more
wiley   +1 more source

Gut Microbiota and Cardiovascular Uremic Toxicities

open access: yesToxins, 2018
Cardiovascular disease (CVD) remains a major cause of high morbidity and mortality in patients with chronic kidney disease (CKD). Numerous CVD risk factors in CKD patients have been described, but these do not fully explain the high pervasiveness of CVD ...
Manuel T. Velasquez   +4 more
doaj   +1 more source

The effect of rural-to-urban migration on renal function in an Indian population: cross-sectional data from the Hyderabad arm of the Indian Migration Study. [PDF]

open access: yes, 2013
BACKGROUND: Urban migration is associated with an increased risk of hypertension, obesity and diabetes in Indian migrants. This study assessed the relationship between internal migration and renal function in the Hyderabad arm of the Indian Migration ...
Bailey, Phillippa K   +7 more
core   +2 more sources

Core determinants of quality criteria for mhealth for hypertension: evidence from machine learning instruments [PDF]

open access: yesarXiv, 2023
Uncontrolled hypertension is a global problem that needs to be addressed. Despite the many mHealth solutions in the market, the nonadherence relative to intended use jeopardizes treatment success. Although investigating user experience is one of the most important mechanisms for understanding mHealth discontinuance, surprisingly, the core determinants ...
arxiv  

Exercise without Weight Loss Prevents Seasonal Decline in Vitamin D Metabolites: The VitaDEx Randomized Controlled Trial

open access: yesAdvanced Science, EarlyView.
In people with overweight or obesity, regular exercise even without weight loss or vitamin D supplementation completely prevents the usual winter decline in the vitamin D metabolite that maintains health at a cellular level, 1,25(OH)2D3, and ameliorates the decline in the vitamin D status marker 25(OH)D.
Oliver J. Perkin   +11 more
wiley   +1 more source

Nephrotic syndrome in very elderly: Should we treat aggressively?

open access: yesClinics and Practice, 2018
Chronic kidney disease and acute kidney injury are being increasingly recognized in very elderly patients, aged 80 or more. In cases of suspected glomerulonephritis with or without nephrotic syndrome, the clinical decision-making of whether to obtain a ...
Abhilash Koratala, Jogiraju Tantravahi
doaj   +1 more source

Renal Oxidative Stress Induced by Long-Term Hyperuricemia Alters Mitochondrial Function and Maintains Systemic Hypertension

open access: yesOxidative Medicine and Cellular Longevity, 2015
We addressed if oxidative stress in the renal cortex plays a role in the induction of hypertension and mitochondrial alterations in hyperuricemia. A second objective was to evaluate whether the long-term treatment with the antioxidant Tempol prevents ...
Magdalena Cristóbal-García   +11 more
semanticscholar   +1 more source

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