Results 81 to 90 of about 1,479,001 (304)

Caregiver Perspectives on the Burden of Disease and Treatment in Uncontrolled Gout

Arthritis Care &Research, EarlyView.
Objective Uncontrolled gout (UG) refers to persistently elevated serum urate (SU) levels >6 mg/dL and ongoing gout symptoms despite use of urate‐lowering therapy (ULT). The objective of this study was to evaluate the burden associated with informal caregiving for individuals with UG.
Angelo Gaffo, Bhavisha Desai, Abiola Oladapo, Nana Kragh, Rebekah Zincavage, Brad Padilla, Naomi Schlesinger   +6 more
wiley   +1 more source

HDAC9 is an epigenetic repressor of kidney angiotensinogen establishing a sex difference

Biology of Sex Differences, 2017
Background Sexual difference has been shown in the pathogenesis of chronic kidney disease induced by hypertension. Females are protected from hypertension and related end-organ damage.
Camille T. Bourgeois, Ryousuke Satou, Minolfa C. Prieto   +2 more
doaj   +1 more source

Microvascular Damage Is Associated With Carotid Wall Structural Changes in Systemic Sclerosis: A Capillaroscopy and Ultrasound‐Based Observational Study

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli, Luca Clerici, Francesco Lapia, Giusy C. Moltisanti, Eleonora Zaccara, Greta Pellegrino, Daniela Bompane, Francesca Capelli, Letizia Ferrami, Laura Castelnovo, Antonio Tamburello, Maria Sole Chimenti, Paola Faggioli, Antonino Mazzone   +13 more
wiley   +1 more source

End-Stage Kidney Disease From Scleroderma in the United States, 1996 to 2012

Kidney International Reports, 2018
Although the management of scleroderma continues to evolve, it is unknown whether the burden of end-stage kidney disease (ESKD) treated with maintenance renal replacement therapy from SD has changed.
Donal J. Sexton, Scott Reule, Robert N. Foley   +2 more
doaj   +1 more source

Rheumatoid arthritis, frailty, and outcomes of surgical hospitalizations: A national population‐based analysis

Arthritis Care &Research, Accepted Article.
OBJECTIVE Hospitalization, particularly for surgery, represents a period of heightened stress. We evaluated how frailty attenuates the association of rheumatoid arthritis (RA) with negative health outcomes after elective non‐cardiac surgery. METHODS We conducted a cross‐sectional study using the National Inpatient Sample (2018 to 2020), including ...
Ali Yazdanyar, Joshua Baker, Katherine D Wysham, Mohammed Yousufuddin, Farah Acher Kaiksow, Michael M. Ward   +5 more
wiley   +1 more source

Increased renal sympathetic nerve activity leads to hypertension and renal dysfunction in offspring from diabetic mothers [PDF]

, 2013
Rodrigues AF, de Lima IL, Bergamaschi CT, Campos RR, Hirata AE, Schoorlemmer GH, Gomes GN. Increased renal sympathetic nerve activity leads to hypertension and renal dysfunction in offspring from diabetic mothers.
Guus Hermanus Maria Schoorlemmer, Ruy Ribeiro Campos, Brites de Lima, Ingrid Lauren [UNIFESP], Bergamaschi, Cassia Toledo [UNIFESP], Maria Schoorlemmer, Guus Hermanus [UNIFESP], Gomes, Guiomar Nascimento [UNIFESP], Aparecida Emiko Hirata, Ingrid Lauren Brites de Lima, Guiomar Nascimento Gomes, Hirata, Aparecida Emiko [UNIFESP], Almeida Chaves Rodrigues, Aline Fernanda de [UNIFESP], Cássia Toledo Bergamaschi, Campos, Ruy Ribeiro [UNIFESP], Aline Fernanda de Almeida Chaves Rodrigues   +13 more
core   +1 more source

Real‐World Safety of Concomitant Colchicine and Statin Therapy

Arthritis Care &Research, EarlyView.
Objective This study aimed to evaluate the risk of clinically meaningful muscle‐ and liver‐related outcomes associated with concomitant colchicine–statin therapy in a real‐world setting, and to determine whether concomitant therapy increases the incidence of toxicity compared with either agent alone.
Roni Meidan, Ranel Loutati, Dan Caspi, Ori Elkayam, Ran Abuhasira, Tali Eviatar   +5 more
wiley   +1 more source

Gut Microbiota and Cardiovascular Uremic Toxicities

Toxins, 2018
Cardiovascular disease (CVD) remains a major cause of high morbidity and mortality in patients with chronic kidney disease (CKD). Numerous CVD risk factors in CKD patients have been described, but these do not fully explain the high pervasiveness of CVD ...
Manuel T. Velasquez, Patricia Centron, Ian Barrows, Rama Dwivedi, Dominic S. Raj   +4 more
doaj   +1 more source

Hypertension and Renal Diseases

American Journal of Kidney Diseases, 1987
Experimental data are summarized that provide evidence that enhanced transmission of systemic hypertension to the glomerulus occurs in the setting of reduced renal mass. It is proposed that similar adaptive glomerular hemodynamic alterations occur in parenchymal renal disease in humans, favoring the development of intraorgan hypertension.
D S, Baldwin, J, Neugarten
openaire   +2 more sources

The effect of rural-to-urban migration on renal function in an Indian population: cross-sectional data from the Hyderabad arm of the Indian Migration Study. [PDF]

, 2013
BACKGROUND: Urban migration is associated with an increased risk of hypertension, obesity and diabetes in Indian migrants. This study assessed the relationship between internal migration and renal function in the Hyderabad arm of the Indian Migration ...
Kuper, Hannah, Bailey, Phillippa, Ebrahim, Shah B J, Tomson, Charles RV, V Radhakrishna, K, Tomson, Charles, Bailey, Phillippa K, Nitsch, Dorothea, Kinra, Sanjay, Ben-Shlomo, Yoav, Ebrahim, Shah, Radhakrishna, KV   +11 more
core   +1 more source