Results 61 to 70 of about 2,652,994 (308)

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

Two transplant renal arteries: One important lesson

Clinical Case Reports, 2018
Key Clinical Message High index of suspicion is required for ischemic nephropathy in renal transplant recipients presenting with unexplained acute kidney injury, as it is potentially reversible.
Abhilash Koratala, Alejandra Mena Gutierrez, Gajapathiraju Chamarthi, Xu Zeng, Kawther F. Alquadan   +4 more
doaj   +1 more source

Human Kidney Tubule-Specific Gene Expression Based Dissection of Chronic Kidney Disease Traits

EBioMedicine, 2017
Chronic kidney disease (CKD) has diverse phenotypic manifestations including structural (such as fibrosis) and functional (such as glomerular filtration rate and albuminuria) alterations.
Pazit Beckerman, Chengxiang Qiu, Jihwan Park, Nora Ledo, Yi-An Ko, Ae-Seo Deok Park, Sang-Youb Han, Peter Choi, Matthew Palmer, Katalin Susztak   +9 more
doaj   +1 more source

Assessing the Sensitivity and the Clinical Impact of the 2023 American College of Rheumatology/EULAR Classification Criteria in Obstetric Antiphospholid Syndrome: Findings From a Multicenter Italian Cohort With a Long‐Term Follow‐Up

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli, Cecilia Nalli, Francesca Crisafulli, Carlo Garaffoni, Marcello Govoni, Giulia Voltarel, Alba C. Pozzi, Beatrice Maranini, Ettore Silvagni, Alessandra Bortoluzzi, Angela Tincani   +10 more
wiley   +1 more source

Effects of sodium bicarbonate therapy on cognitive and cerebrovascular function in midlife and older adults with chronic kidney disease: a pilot randomized trial

BMC Nephrology
Introduction Metabolic acidosis may create a pathway to cognitive impairment in chronic kidney disease (CKD) by contributing to cerebrovascular dysfunction.
Fangning Gu, Zhiying You, Nell Hawkins, Rachael Reddin, Rahaf Hamour, Allison Shapiro, Christina Coughlan, Douglas Seals, Seth Furgeson, Angelina Dixon, Kristen L. Nowak, Jessica Kendrick   +11 more
doaj   +1 more source

Safety and Effectiveness of Daratumumab in Recurrent and De Novo Focal Segmental Glomerulosclerosis After Kidney Transplant

Kidney Medicine
Daratumumab, an anti-CD38 monoclonal antibody targeting plasma cells, has emerged as a potential therapy for recurrent focal segmental glomerulosclerosis (FSGS) after kidney transplantation; however, data on subcutaneous administration and its use in de ...
Rohan V. Mehta, Kayla B. Evans, Chintan V. Shah, Ashutosh Shukla, Amer Belal, Hisham Ibrahim, Kawther Alquadan, Muhannad Leghrouz, Georgios Vrakas, Rahul Mehta, Alfonso Santos   +10 more
doaj   +1 more source

Mediators of Inflammation in Acute Kidney Injury

Mediators of Inflammation, 2009
Acute kidney injury (AKI) remains to be an independent risk factor for mortality and morbidity. Inflammation is now believed to play a major role in the pathopathophysiology of AKI.
Ali Akcay, Quocan Nguyen, Charles L. Edelstein   +2 more
doaj   +1 more source

Bioactive lipid mediators in polycystic kidney disease

Journal of Lipid Research, 2014
Inflammatory activity is evident in patients with chronic kidney disease with limited data available in autosomal dominant polycystic kidney disease (ADPKD). We hypothesized that inflammation is an upstream event in the pathogenesis of ADPKD and may be a
Jelena Klawitter, Jost Klawitter, Kim McFann, Alexander T. Pennington, Kaleab Z. Abebe, Godela Brosnahan, Melissa A. Cadnapaphornchai, Michel Chonchol, Berenice Gitomer, Uwe Christians, Robert W. Schrier   +10 more
doaj   +1 more source

Effects of Causal Beliefs About Gout on Public Views About Gout Management: A Randomized Experimental Study

Arthritis Care &Research, EarlyView.
Objective Despite well‐described biologic causes, the public views unhealthy lifestyle choices as the primary cause of gout. This study investigated how causal beliefs about gout influence the public's views about its management. Methods In a randomized study, 201 members of the public viewed one of two 2‐minute videos about gout.
Rachel Murdoch, Borislav Mihov, Anne Horne, Keith J. Petrie, Gregory D. Gamble, Lachlan Fleck, Nicola Dalbeth   +6 more
wiley   +1 more source

Hypertension and Renal Disease

Renal Failure, 1993
Chronic renal parenchymal disease is the most common cause of secondary hypertension: By the time end-stage renal disease develops, its prevalence approaches 75-85%. It was previously believed that hypertension caused arteriolar nephrosclerosis and ischemic renal injury superimposed on primary renal parenchymal disease, contributing to progressive ...
G A, Cinotti, C, Comunian
openaire   +2 more sources