HDAC9 is an epigenetic repressor of kidney angiotensinogen establishing a sex difference
Background Sexual difference has been shown in the pathogenesis of chronic kidney disease induced by hypertension. Females are protected from hypertension and related end-organ damage.
Camille T. Bourgeois +2 more
doaj +1 more source
Occurrence of acute oesophageal necrosis (black oesophagus) in a single tertiary centre [PDF]
Acute oesophageal necrosis (AON) is a rare condition characterised by the endoscopic finding of diffuse, circumferential, black mucosal pigmentation of the oesophagus, which typically stops at the gastro-oesophageal junction.
Annibale, Bruno +6 more
core +1 more source
End-Stage Kidney Disease From Scleroderma in the United States, 1996 to 2012
Although the management of scleroderma continues to evolve, it is unknown whether the burden of end-stage kidney disease (ESKD) treated with maintenance renal replacement therapy from SD has changed.
Donal J. Sexton +2 more
doaj +1 more source
Genomics and precision medicine for clinicians and scientists in hypertension [PDF]
No abstract ...
Delles, Christian +2 more
core +1 more source
Gut Microbiota and Cardiovascular Uremic Toxicities
Cardiovascular disease (CVD) remains a major cause of high morbidity and mortality in patients with chronic kidney disease (CKD). Numerous CVD risk factors in CKD patients have been described, but these do not fully explain the high pervasiveness of CVD ...
Manuel T. Velasquez +4 more
doaj +1 more source
TIPS for the treatment of refractory ascites, hepatorenal syndrome and hepatic hydrothorax: a critical update [PDF]
Refractory ascites is a frequent complication of advanced cirrhosis and is associated with hepatorenal syndrome and hepatic hydrothorax. Large volume paracentesis and pleurodesis are regarded as first-line treatments in patients who do not respond ...
Gerbes, Alexander L., Roessle, Martin
core +1 more source
Evaluating techniques in tissue clarification using CLARITY imaging and investigating where sodium is sensed in the body [PDF]
OBJECTIVE: Previous studies have shown the significant contribution of sympathoinhibition in response to sodium loading to prevent increases in mean arterial blood pressure in salt resistant phenotypes.
Neal, Christopher Matthew
core +1 more source
Atrial natriuretic factor [PDF]
The discovery of the first well-defined natriuretic hormone, the Atrial Natriuretic Factor (ANF), has prompted research on its impact on volume regulation in health and disease.
A.L. Gerbes +99 more
core +1 more source
Nephrotic syndrome in very elderly: Should we treat aggressively?
Chronic kidney disease and acute kidney injury are being increasingly recognized in very elderly patients, aged 80 or more. In cases of suspected glomerulonephritis with or without nephrotic syndrome, the clinical decision-making of whether to obtain a ...
Abhilash Koratala, Jogiraju Tantravahi
doaj +1 more source
Preimplantation biopsy predicts delayed graft function, glomerular filtration rate and long-term graft survival of transplanted kidneys [PDF]
Background The predictive value of preimplantation biopsies for long-term graft function is often limited by conflicting results. The aim of this study was to evaluate the influence of time-zero graft biopsy histological scores on early and late graft ...
Bianchi, Valentina +10 more
core +2 more sources

