Results 91 to 100 of about 1,479,001 (304)

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension [PDF]

, 2011
Background: Endothelin-1 signalling plays an important role in pathogenesis of pulmonary hypertension. Although different endothelin-A receptor antagonists are developed, a novel therapeutic option to cure the disease is still needed.
Norbert Weissmann, Sydykov, Akylbek, Brandes, Ralf, Schermuly, Ralph T., Hossein A Ghofrani, Janssen, Wiebke, Seeger Werner, Ralf P Brandes, Neil Davie, Dahal, Bhola K., Davie, Neil, Janssen Wiebke, Davie Neil, Ghofrani Hossein A, Seeger, Werner, Cornitescu, Teodora, Brandes Ralf P, Cornitescu Teodora, Kosanovic, Djuro, Kojonazarov, Baktybek, Werner Seeger, Friedrich Grimminger, Ghofrani, Hossein Ardeschir, Grimminger, Friedrich, Dahal Bhola K, Djuro Kosanovic, Baktybek Kojonazarov, Teodora Cornitescu, Schermuly Ralph T, Sydykov Akylbek, Wiebke Janssen, Grimminger Friedrich, Akylbek Sydykov, Kojonazarov Baktybek, Weissmann Norbert, Himal Luitel, Luitel Himal, Ralph T Schermuly, Luitel, Himal, Weißmann, Norbert, Bhola K Dahal, Kosanovic Djuro   +41 more
core   +2 more sources

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source

Predictors of accelerated renal function decline in the general population [PDF]

, 2010
Nederlandse samenvatting Proefschrift: ‘Predictors of accelerated Renal function decline in the general population Nynke Halbesma Het aantal mensen met een chronische nierziekte is sterk toegenomen.
Halbesma, Nynke,, Halbesma, Nynke
core   +14 more sources

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

Advanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu, Shimin Jiang, Zhenkun Yang, Shunlai Shang, Jiayi Li, Guming Zou, Cheng Zhou, Wenge Li   +7 more
wiley   +1 more source

INAPPROPRIATE LEFT VENTRICULAR MASS, IN CHILDREN WITH PREDYALITIC CHRONIC RENAL INSUFFICIENCY [PDF]

, 2008
Background: Increased left ventricular (LV) mass in children with chronic renal insufficiency (CRI) might represent an adaptive mechanism to compensate for increased workload.
Romano, Carmela
core   +1 more source

Hypertension and renal failure [PDF]

Clinical Medicine, 2002
Sunil, Nadar, D Gareth, Beevers, Gregory Y H, Lip   +2 more
openaire   +4 more sources

Nephrotic syndrome in very elderly: Should we treat aggressively?

Clinics and Practice, 2018
Chronic kidney disease and acute kidney injury are being increasingly recognized in very elderly patients, aged 80 or more. In cases of suspected glomerulonephritis with or without nephrotic syndrome, the clinical decision-making of whether to obtain a ...
Abhilash Koratala, Jogiraju Tantravahi
doaj   +1 more source

Salt-Sensitive Hypertension, Renal Injury, and Renal Vasodysfunction Associated With Dahl Salt-Sensitive Rats Are Abolished in Consomic SS.BN1 Rats. [PDF]

J Am Heart Assoc, 2021
Potter JC, Whiles SA, Miles CB, Whiles JB, Mitchell MA, Biederman BE, Dawoud FM, Breuel KF, Williamson GA, Picken MM, Polichnowski AJ.   +10 more
europepmc   +1 more source

THE RENAL ORIGIN OF HYPERTENSION

Physiological Reviews, 1947
Bibliography: p. 119. ; Mode of access: Internet.
openaire   +3 more sources