Results 101 to 110 of about 2,904,733 (344)
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel +8 morewiley +1 more sourceLifestyle modification and hypertension prevention [PDF]
BACKGROUND: Hypertension, a clear risk factor for cardiovascular diseases, affects nearly one
billion people worldwide. Recent statistics have reported increasing mortality due to
hypertension which reveals the importance of prophylactic strategies in ...قربانی, اعظم, قزلباش, سيما +1 morecore Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension [PDF]
, 2010 Hypertension is a heritable and major contributor to the global burden of disease. The sum of rare and common genetic variants robustly identified so far explain only 1%–2% of the population variation in BP and hypertension.Zanchetti A, Wichmann HE, Samani, NJ, Munroe, P., Navis G, P. Sever (7602536), Hastie, Claire E., A. H. Baker (7611224), Martina Montagnana, McDonald, Robert A., Wahlstrand, B, Kathiresan, S., Snieder, Harold; id_orcid, Völzke Henry, Ruth J. F. Loos, Nicklin, SA, Morris Brown, Nolte IM, Wichmann, H.-E., Kathiresan S, Padmanabhan Sandosh, Zhang Feng, M. Montagnana (7611173), Caulfield MJ, Rettig Rainer, Laan, Maris, Rettig, Rainer, J. Luan (7609367), Mc Donald, R.A., Melander, Olle,, Peter Vollenweider, Sever, P, Nicklin Suart, A., Zanchetti, A., Hedblad, Bo, Ole Torffvit, A. Teumer (7609454), Stewart Laing, Hastie, CE, P. Welsh (7611230), M. Burnier (7611161), Bochud, Murielle, Miller, WH, Wichmann, H.E., Martin Farrall, Montagnana M, Caulfield Mark J., M. C. Monti (7611146), J. P. Pell (6240134), Michel Burnier, Eyheramendy, S., Maris Laan, David P Strachan, Snieder Harold, Connell JMC, Vollenweider Peter, Connell, JMC, Signorini S, Zhang, F, Newton-Cheh Christopher, Laing, Stewart, M. Farrall (6522599), Stanton Alice, Timothy D Spector, Mark J. Caulfield, Sattar, N, B. Corso (7611152), Gentilini D, Kwakernaak, A.J., McDonald RA, Penninx Brenda W., W. H. Miller (7611218), Spector Timothy, D., Conell, J.M.C., Fava, Cristiano,, Shields, D.C., Kjeldsen, S, Samani Nilesh, J., Strachan, David P., Corso, B., Timothy D. Spector, Montagnana Martina, Pell JP, Nicklin Stuart A., D. S. Siscovick (7611209), Welsh, P., Johnson, T, Connell, John M. C., Penninx, B.W.J.H., Johnson, T., Naveed Sattar, Sjögren, M, Bochud Murielle, Torffvit, O, Sever Peter, Kjeldsen Sverre, G. Grassi (2592760), Navis, G., Laan, M., Padmanabhan S, Johnson T, S. Laing (7611149), Nolte Ilja, M., C. Delles (7602479), Jill P. Pell, Miller William H., Shields Denis, Colm, Lucas, Gavin, Dominiczak A.F., Connell John M. C., Snieder, H, Mark J Caulfield, Snieder H, Caulfield, M.J., A. J. Kwakernaak (3694963), Newton Cheh C, Stuart A. Nicklin, Connell John, M.C., Wahlstrand, Björn, Hedblad, Bo,, Newton-Cheh C, Brown, M., Laing S, Montagnana, Martina,, Brown Morris, Hedner, Thomas, Wareham, N.J., A. M. Di Blasio (7611140), Graham, D, Miller, W.H., Nicholas J Wareham, Rettig R, David S Siscovick, Nicholas J. Wareham, Nolte, Ilja M., F. Zhang (2167666), David S. Siscovick, Loos, Ruth J. F., McDonald Robert, A., Burnier, M, G. Mancia (7611191), Nolte Ilja M., Arora, Pankaj, Murielle Bochud, Cristina Menni, Loos, RJF, Cesana Giancarlo, Sjögren, Marketa, Baker, Andrew H., Nolte, Ilja M.; id_orcid, Welsh P, Lund University., van der Harst, Pim, Welsh, P, Monti Maria Cristina, Völzke, H, Bochud M, Sever, Peter, Baker, AH, Hedner Thomas, van der Harst, Pim; id_orcid, Maillard, Marc, Torffvit, O., Stanton, A, Wareham NJ, Kjeldsen, Sverre, Wahlstrand B, Lee, WK, B. Hedblad (7611182), S. Kathiresan (7606013), Brenda W Penninx, Spector Timothy D., Lee, W.K., Teumer, A., Toby Johnson, McBride, M, Menni Cristina, Fava Cristiano, Pim van der Harst, Penninx, Brenda W., Susana Eyheramendy, Wareham, NJ, Connell, John M.C., Teumer, A, Barbara Corso, Melander, O, Wareham Nicholas, J., Penninx, B.W., Ruth J F Loos, Claire E Hastie, Shields, Denis Colm, Alberto Zanchetti, Peter Sever, Lee Wai K., Torffvit Ole, Delles, C, Luan, J., Cristiano Fava, McBride Martin, Mancia, G., Gavin Lucas, Shields DC, Luan, Jian'an, Zhang, Feng, Arora Pankaj, Björn Wahlstrand, John M C Connell, Newton-Cheh, C, Wareham, Nicholas J., Cesana, Giancarlo, Snieder, Harold, Melander Olle, Eyheramendy, Susana, Di Blasio, A.M., Torffvit, Ole, McBride, Martin, Maillard Marc, Corso B, Schork, Nicholas J., van der Harst Pim, Nolte, IM, T. Johnson (7602368), Teumer Alexander, D. Graham (29758), Loos Ruth, J.F., Monti Maria, Cristina, Hastie Claire E., S. A. Nicklin (7611221), M. Bochud (7611158), Kwakernaak Arjan, J., Global BPgen Consortium (7611233), Sjögren M, Voelzke, Henry, Vollenweider, P, Delles, Christian, Monti, M.C., Stanton, A., Grassi, G, Grassi, G., van der Harst P, Strachan, DP, Eyheramendy Susana, Soranzo Nicole, Danese Elisa, Gentilini, D, Fava, C, Hedner, T, Spector, TD, Navis, G, B. W. Penninx (7611212), Luan, JA, Connell JM, M. Maillard (3464312), Delles Christian, Luan, Jian'an, Montagnana, Martina, Pell, JP, Hastie CE, Eyheramendy S, Robert A. McDonald, Menni C, Luan J, Anna F Dominiczak, Connell, JM, Caulfield, Mark J., Di Blasio, AM, Burnier, M., Monti, MC, Siscovick David, S., Kwakernaak, Arjan J., Signorini, Stefano, Henry Völzke, Stuart A Nicklin, van der Harst, P, Loos RJ, Hedblad B, Strachan David P., Nolte, I.M., Pell Jill P., Burnier, Michel, Munroe P, W. K. Lee (7602476), H Erich Wichmann, null null, Ilja M. Nolte, Giuseppe Mancia, Monti, Maria Cristina, Menni, C, Farrall Martin, Brown, M, Montagnana, M., Samani, Nilesh J., Nilesh J. Samani (7579793), S. Signorini (7611194), McDonald, R.A., Farrall, M, Anna Maria Di Blasio, T. D. Spector (7608968), Baker Andrew H., Sever P, Loos RJF, Penninx Brenda, W., Vollenweider, P., Marc Maillard, Sattar Naveed, Wahlstrand Björn, John M. C. Connell, Newton-Cheh, Christopher, Kwakernaak AJ, Soranzo, N, Bochud, M., M. Laan (7602659), Fava C, Penninx, BW, Sattar, Naveed, Kjeldsen S, Snieder, H., Martin McBride, Graham Delyth, Vollenweider P, G. Cesana (7611188), Mancia G, Brenda W. Penninx, O. Torffvit (7611179), D. P. Strachan (3809152), Newton-Cheh, C., A. Stanton (7611200), R. J. Loos (7608845), McDonald, RA, Danese, E., David P. Strachan, Nicklin SA, William H. Miller, Siscovick, DS, M. Sjögren (7611167), Pell, Jill P., Arora P, C. E. Hastie (7602473), H. Snieder (7611185), Signorini, S, McDonald Robert A., Ilja M Nolte, Dominiczak Anna, F., Miller, William H., Cesana, G, Stefano Signorini, Guido Grassi, I. M. Nolte (3809176), Blasio, A.M. Di, Samani, N.J., Wichmann H. Erich,, D. Gentilini (4402804), Kathiresan, S, Gerjan Navis, Harold Snieder, Samani NJ, Rettig, R, Feng Zhang, Baker, A.H., Siscovick David S., P. van der Harst (7594607), Pell Jill, P., Burnier Michel, Soranzo, N., Dominiczak, A.F., Mancia Giuseppe, Padmanabhan, Sandosh, Torffvit O, Gentilini, Davide, Völzke, Henry, Stanton A, Di Blasio Anna, Maria, van der Harst, P., Wichmann, HE, H. Erich Wichmann, Lucas, G, Mancia, G, Zanchetti, A, Mancia, Giuseppe, M. McBride (7611215), Elisa Danese, Zhang, F., Fava, Cristiano, Denis Colm Shields, Feng, Zhang, Menni, C., Laing, S., Global BPgen Consortium, Andrew H Baker, Thomas Hedner, P. Munroe (7609094), Spector, Timothy D., C. Newton-Cheh (7602563), Lee WK, Munroe, Patricia, Delyth Graham, Torffvit, Ole,, Delles, C., Hedblad, B, Sverre Kjeldsen, Wahlstrand, B., Robert A McDonald, Sjögren Marketa, Grassi G, N. Sattar (7608890), Farrall, M., O. Melander (7602683), Teumer, Alexander, Olle Melander, Dominiczak, Anna F., Kwakernaak Arjan J., Di Blasio Anna Maria, Navis Gerjan, D. C. Shields (7602542), Laan, M, Kwakernaak A, Laing Stewart, Zanchetti Alberto, Zhang F, Cesana, G., G. Navis (7611155), Siscovick, David S., C. Fava (7611170), Pell, J.P., Munroe Patricia, Siscovick DS, Melander O, Jill P Pell, Nilesh J. Samani, Strachan, D.P., Corso Barbara, Fava, C., Lucas Gavin, Maillard, M, Lucas G, N. Soranzo (7608857), Baker Andrew, H., Hastie, C.E., Sever, P., Farrall, Martin, Laan M, Hedner, T., Davide Gentilini, Corso, B, Samani Nilesh J., S. Padmanabhan (637530), Giancarlo Cesana, Stanton, Alice, Shields Denis Colm, William H Miller, Graham, Delyth, Völzke H, Sekar Kathiresan, Hedblad Bo, Danese, Elisa, Bo Hedblad, Maillard M, Miller William, H., Melander, O., Montagnana, M, Vollenweider, Peter, Burnier M, T. Hedner (7602677), Wareham Nicholas J., Wai K Lee, A. Zanchetti (7611236), Soranzo, Nicole, P. Arora (7611206), Völzke, H., Andrew H. Baker, Connell, J.M.C., Johnson, Toby, Miller WH, Strachan David, P., Sattar, N., C. Menni (7611143), B. Wahlstrand (7602680), Di Blasio AM, Sattar N, Rettig, R., Signorini Stefano, Christian Delles, Arjan J Kwakernaak, Luan Jian'an, Siscovick, D.S., Harst, Pim van der, H. Völzke (6643736), Marketa Sjögren, Danese, E, Hastie Claire, E., Monti MC, Penninx BW, Lee Wai, K., Caulfield, MJ, Christopher Newton-Cheh, Harst, P. van der, Dominiczak, AF, Arjan J. Kwakernaak, Caulfield Mark, J., Nicole Soranzo, J. M. Connell (7602551), Johnson Toby, Gentilini, D., Loos, RJ, Rainer Rettig, Anna F. Dominiczak, Loos Ruth J. F., G. Lucas (7606529), Padmanabhan, S, Teumer A, Brown, Morris, Bochud, M, Dominiczak Anna F., S. Eyheramendy (7611197), Wichmann, Heinz-Erich, Grassi, Guido, Hedblad, B., Alexander Teumer, Hedner T, Munroe, P, Wai K. Lee, Luan, J, M. Brown (3020991), Luan JA, Danese E, Welsh, Paul, Laing, S, Welsh Paul, Spector TD, Pankaj Arora, Patricia Munroe, Newton Cheh, Christopher, Maria Cristina Monti, Melander, Olle, Delles C, Graham D, H. E. Wichmann (7608932), Padmanabhan, S., R. A. McDonald (7611227), A. F. Dominiczak (7602482), Spector, T.D., Kwakernaak, AJ, Baker AH, Loos, R.J.F., Zanchetti, Alberto, Navis, Gerjan, Sjögren, Marketa,, Graham, D., Wichmann, H. Erich, Claire E. Hastie, Farrall M, N. J. Wareham (7608962), Eyheramendy, S, Kathiresan, Sekar, M. J. Caulfield (7602383), Nicklin, S.A., P. Vollenweider (4002164), Gentilini Davide, S. Kjeldsen (7611164), Arora, P, E. Danese (7611176), Sjögren, M., Laan Maris, Nicklin, Stuart A., Menni, Cristina, Signorini, S., Gentilini, G., Arora, P., Alice Stanton, Dominiczak AF, R. Rettig (7611203), Kathiresan Sekar, Paul Welsh, Maillard, M., Soranzo N, Corso, Barbara, Cesana G, Sandosh Padmanabhan, Di Blasio, Anna Maria, Jian'an Luan, Grassi Guido, McBride, M., Strachan DP, Shields, DC, Wichmann H. Erich, Lee, Wai K., Nilesh J Samani, Brown M, Lucas, G., Luan, J.A., McBride M, Kjeldsen, S. +591 morecore +4 more sourcesInteraction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction/Objective
Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.Aaron Rodriguez‐Calienes, Leonardo Cruz‐Criollo, Eric Kontowicz, Marta Olivé‐Gadea, Francesco Diana, Johannes Kaesmacher, Adnan Mujanovic, Serdar Geyik, Songul Senadim, Amedeo Cervo, Andrea Salcuni, Mariangela Piano, Manuel Moreu, Alfonso López‐Frías, Ameer E. Hassan, Samantha Miller, Elena Zapata‐Arriaza, Asier de Albóniga‐Chindurza, Mauro Bergui, Stefano Molinaro, João André Sousa, Fábio Gomes, João Sargento‐Freitas, Andrea Alexandre, Alessandro Pedicelli, Jeremy Hofmeister, Paolo Machi, Luca Scarcia, Erwah Kalsoum, Jose Amorim, Torcato Meira, Leonardo Renieri, Francesco Capasso, Daniele Romano, Eduardo Bárcena‐Ruiz, David Seoane, Mohamad Abdalkader, Piers Klein, Thanh N. Nguyen, Catarina Perry da Câmara, Anderson Brito, Nashwa Abdelhakim, Isabel Fragata, Dileep R. Yavagal, Jude H. Charles, Jose Rodriguez Castro, Pedro Vega, Atilla Özcan Özdemir, Zehra Uysal Kocabaş, Stanislas Smajda, Sadiq Al Salman, Jane Khalife, Tudor G. Jovin, Francesco Biraschi, Francesca Richetti, Pedro Castro, Luis Albuquerque, Adnan Siddiqui, Vinay Jaikumar, Pedro Navia, Nikolaos Ntoulias, Marios Psychogios, Mariano Velo, Joaquín Zamarro, Gonzalo de Paco, Yazan Ashouri, Mohammad AlMajali, Juan F. Arenillas, Alicia Sierra, Michele Romoli, João Pedro Marto, Shadi Yaghi, Marc Ribo, Alejandro Tomasello, Manuel Requena, Santiago Ortega‐Gutierrez +75 morewiley +1 more sourceEffects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background
Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily +5 morewiley +1 more sourceIntegrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue +10 morewiley +1 more sourceKidney function in the very elderly with hypertension: data from the hypertension in the very elderly (HYVET) trial.
, 2013 BACKGROUND: numerous reports have linked impaired kidney function to a higher risk of cardiovascular events and mortality. There are relatively few data relating to kidney function in the very elderly. METHODS: the Hypertension in the Very Elderly Trial (Narkiewicz, Krzysztof, Beckett, Nigel, Fagard, Robert, Bulpitt, Christopher, Wang, Nan, Fletcher, Astrid, Peters, Ruth, Nitsch, Dorothea, Burch, Lisa, Li, Mengying, Poulter, Ruth +10 morecore +1 more source
