Results 171 to 180 of about 2,904,733 (344)
Objective Routine liver enzyme monitoring is advocated while on allopurinol but supporting guidance is lacking. We assessed the incidence and factors associated with elevated liver enzymes in gout patients commenced on allopurinol. Methods 150 patients with gout and normal baseline serum aminotransferases initiated on allopurinol were followed ...
May Shuen Tang +4 more
wiley +1 more source
The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019)
S. Umemura +44 more
semanticscholar +1 more source
Hypertension among adults in the United States, 2009-2010 [PDF]
Significant increases have been seen over the past 10 years in hypertension awareness, treatment, and control among adults with hypertension. However, less than 50% of adults with hypertension controlled their blood pressure (BP) in 2007\u20132008 (1 ...
core
Charting Morphotoxicity With Complementary Embryo Models
Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx +9 more
wiley +1 more source
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi +10 more
wiley +1 more source
High altitude pulmonary hypertension: overlap with other types of pulmonary hypertension and implications for treatment. [PDF]
Forbes LM, Lahm T.
europepmc +1 more source
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang +11 more
wiley +1 more source

