Results 191 to 200 of about 2,704,025 (289)

Targeting Histamine H4 Receptor in the Rostral Ventromedial Medulla to Relieve Hypertension

Advanced Science, EarlyView.
H4R and its downstream TRPV1 channel mediate the excitatory effect of TMN histaminergic afferent inputs on GABAergic sympathoinhibitory neurons in RVMM. Intranasal delivery of selective H4R agonist VUF 8430 suppresses renal sympathetic outflow and elicits sustained depressor and bradycardia responses in SHRs and CUMS‐induced hypertensive rats ...
Ying Shi, Yang‐Xun Zhang, Jun‐Yi Chen, Sai Ma, Wei‐Xuan Xue, Wei Li, Qian‐Xiao Li, Bo Song, Ya‐Ting Li, Hong‐Yu Ma, Shu‐Tao Xie, Hong‐Zhao Li, Di‐Jun Chen, Qi‐Peng Zhang, Hui‐Jie Ma, Jian‐Jun Wang, Lei Yu, Xiao‐Yang Zhang, Jing‐Ning Zhu   +18 more
wiley   +1 more source

Systemic Hypertension and Impaired Glucose Tolerance Are Independently Correlated to the Severity of the Acromegalic Cardiomyopathy¹ [PDF]

, 2000
Annamaria Colao, Roberto Baldelli, Paolo Marzullo, Elisabetta Ferretti, Diego Ferone, Patrizia Gargiulo, Mario Petretta, Guido Tamburrano, Gaetano Lombardi, Antonio Liuzzi   +9 more
openalex   +1 more source

Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells

Advanced Science, EarlyView.
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha, Benjamin Yang, Dongqiang Yuan, Edmund D. Kapelczak, Philip A. Kocheril, Alonso Tapia, Shivansh Mahajan, Adrian Colazo, Naseeb K. Malhi, Joseph A. Ambarian, Xuejing Liu, Tara A. TeSlaa, Zhen B. Chen, Lu Wei   +13 more
wiley   +1 more source

Analysis of Recent Papers in Hypertension

, 2006
Jan Basile, Michael J. Bloch
openalex   +2 more sources

Clinical efficacy and survival with first-line inhaled iloprost therapy in patients with idiopathic pulmonary arterial hypertension [PDF]

, 2005
Christian Opitz, Roland Wensel, Jörg Winkler, Michael Halank, Leonhard Bruch, Franz‐Xaver Kleber, G. Höffken, Stefan D. Anker, Abdissa Negassa, Stephan B. Felix, Roland Hetzer, Ralf Ewert   +11 more
openalex   +1 more source

Microvascular Health as a Key Determinant of Organismal Aging

Advanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini, Andrea Uccelli, Francesca Mangili, Myriam Grunewald, Simone Bersini   +4 more
wiley   +1 more source

Chronic Pain and Hypertension and Mediation Role of Inflammation and Depression. [PDF]

Hypertension
Qin P, Ho FK, Celis-Morales CA, Pell JP.
europepmc   +1 more source

Customer Relationship Management InterventionApplication (CRM) on Drug Interaction and QualityImprovement of Life Patients with Hypertension [PDF]

, 2018
Ari Usmana, Eva Sartika Dasopang, Nilsya FebrikaZebua   +2 more
openalex  

Replication of the Wellcome Trust genome-wide association study of essential hypertension: the Family Blood Pressure Program [PDF]

, 2008
Georg Ehret, Alanna C. Morrison, Ashley O’Connor, Megan L. Grove, Lisa Baird, Karen Schwander, Alan B. Weder, Stephen S. Rich, D. C. Rao, Steven C. Hunt, Eric Boerwinkle, Aravinda Chakravarti   +11 more
openalex   +1 more source

Metabolic Interplay in Acute Lung Injury: PARK7 Integrates FADS1/2‐Dependent PUFA Metabolism and H3K14 Lactylation to Attenuate Endothelial Ferroptosis and Dysfunction

Advanced Science, EarlyView.
SCAP/ARDS patients show reduced unsaturated fatty acids (UFAs) but higher PARK7 and lactate in plasma. PARK7 correlates positively with lactate and negatively with UFAs. Pulmonary endothelial cell multi‐omics show FADS1/2 downregulation and impaired PUFA metabolism. Lactate boosts PARK7 via H3K14 lactylation, and PARK7 then restores FADS1/2.
Jian Xu, Yuhan Wang, Weiqi Mao, Tianchang Wei, Yufan Li, Juan Song, Cuiping Zhang, Xiaoyan Chen, Cuicui Chen, Qingyuan Xu, Xu Wu, Yuanlin Song   +11 more
wiley   +1 more source