Results 211 to 220 of about 2,704,025 (289)

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

Hypertension-attributable stroke burden in younger vs older people: analysis of GBD 2021 and NHANES databases. [PDF]

Am J Prev Cardiol
Li F, Li J, Tan S, Xie M, Wang H, Liu Q.
europepmc   +1 more source

Right heart remodeling in end-stage pulmonary arterial hypertension and the impact of treatment intensity [PDF]

Su‐Gang Gong, Qi-Hang Zhang, Jiayi Zhang, Qian Zhang, Rui Zhang, Hong‐Ling Qiu, Ci‐Jun Luo, Huiting Li, Wen-Hui Wu, Ping Yuan, Jing He, Jian Xu, Jinming Liu, Qin-Hua Zhao, Lan Wang   +14 more
openalex   +1 more source

Prevalence of Hypertension among Urban Slum Dwellers in Lagos, Nigeria [PDF]

, 2013
Olusoji Daniel, Olusola Adedeji Adejumo, Esther Ngozi Adejumo, Rotimi Samuel Owolabi, Rotimi Williams Braimoh   +4 more
openalex   +1 more source

Targeted Degradation of sGRP78 Alleviates the Immunosuppressive Tumor Microenvironment

Advanced Science, EarlyView.
Soluble GRP78 (sGRP78) is identified as a novel tumor‐derived soluble factor that induces regulatory T cells (Treg). sGRP78 serves as an excellent serological biomarker for predicting the efficacy of neoadjuvant therapy in breast cancer patients. sGRP78 specifically binds to B cells, inducing the expression of IL‐10 and PD‐L1, thereby promoting Treg ...
Zhenghao Wu, Peng Zheng, Yunxiao Xiao, Qianheng Wang, Xin Pan, Xiaoqi Zhou, Yibing Lv, Junyi Xiao, Yong He, Tao Huang, Ping Lei   +10 more
wiley   +1 more source

Evaluating the relationship between primary care provider access and high blood pressure among Hispanic patients: a cross-sectional study. [PDF]

J Health Popul Nutr
Yepez C, McKeirnan K, Undeberg M, Pett RG.   +3 more
europepmc   +1 more source

Evaluation of an Academic-Community Partnership to Implement MTM Services in Rural Communities to Improve Pharmaceutical Care for Patients with Diabetes and/or Hypertension [PDF]

, 2018
Melissa Johnson, Rebecca Jastrzab, Jared Tate, KATE JOHNSON, Elizabeth Hall‐Lipsy, Rose Martin, Ann M. Taylor, Terri Warholak   +7 more
openalex   +1 more source

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han, Chunsheng Wang, Xiuli Guo, Yuan Luo, Jianguo Zhang, Fajian He, Zihang Zeng, Jiang Luo, Wen Ouyang, Yan Gong, Conghua Xie   +10 more
wiley   +1 more source

Remnant Cholesterol is Associated with Blood Pressure Control in US Adults with Hypertension: NHANES 2007-2018 Analysis. [PDF]

Vasc Health Risk Manag
Feng S, Zou S, Tang M, Tian R, Xu Y.
europepmc   +1 more source

Non-physician Led Hypertension Management

, 2020
Poupak Moshayedi
openalex   +1 more source