Results 211 to 220 of about 2,746,783 (328)
Fibulin 2 Deficiency Drives Epigenetic Hypertension. [PDF]
Han X, Sun Z.
europepmc +1 more source
Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang +12 more
wiley +1 more source
Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha +13 more
wiley +1 more source
Peripartum Telehealth Care Utilization During the COVID-19 Pandemic, by Hypertension Status, PCORnet®, 2018 to 2023. [PDF]
Kuklina EV +15 more
europepmc +1 more source
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao +5 more
wiley +1 more source
Primary aldosteronism in South Asia: insights from a tertiary outpatient cohort in Bangladesh. [PDF]
Jahan S +5 more
europepmc +1 more source
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu +17 more
wiley +1 more source
A Robust Serum Proteomic Signature of the E2 Allele of Apolipoprotein E
This study expands a serum protein signature of the e2 allele of APOE using multiple proteomic platforms and UK Biobank replication. The signature supports the role of APOE in lipid regulation through apolipoproteins and inflammation and includes, among others, neutrophil secreted granule proteins CAMP, CTSG, DEFA3, and MPO that point to inhibition of ...
Paola Sebastiani +20 more
wiley +1 more source
Interaction between sleep disorder and depression on early onset hypertension: a machine learning modelling approach. [PDF]
Liu F +5 more
europepmc +1 more source

