Results 111 to 120 of about 40,822 (242)

Role of reactive oxygen species in mediating peripheral hypoxic vasodilation and sympathoexcitation at high altitude

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude acclimatisation increases muscle sympathetic nerve activity (MSNA) via activation of the arterial chemoreflex, pulmonary arterial baroreceptors and resetting of the sympathetic vascular baroreflex. However attempting to silence these mechanisms only partially normalises MSNA, implicating other contributory ...
Liam D. Corr   +15 more
wiley   +1 more source

Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu   +3 more
wiley   +1 more source

Effect of Blonanserin on Neurotrophic Factors in Patients With Non‐Responsive First‐Episode Schizophrenia Treated With Early Risperidone Monotherapy—A Randomized Controlled Trial

open access: yesInternational Journal of Methods in Psychiatric Research, Volume 35, Issue 4, December 2026.
ABSTRACT Objective To investigate the efficacy of Blonanserin in patients with schizophrenia who were refractory to Risperidone monotherapy and its effects on various neurotrophic factors. Methods A total of 120 patients with first‐episode schizophrenia who were hospitalized in our hospital from January 2022 to December 2023 and did not respond to ...
Yaxue Wei   +7 more
wiley   +1 more source

A Voxel‐Wise T2 Distribution Framework for Lesion Severity Stratification and Treatment‐Response Assessment in Stroke: Insights Into Suberoylanilide Hydroxamic Acid‐Induced Neuroprotection

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 6, Page 2870-2884, December 2026.
ABSTRACT Purpose To evaluate lesion severity distribution in ischaemic brain lesions in spontaneously hypertensive rats (SHR) subjected to 90‐min transient middle cerebral artery occlusion (tMCAO), and to determine whether epigenetically based neuroprotection modifies lesion severity profiles using a voxel‐wise T2 distribution framework.
Andrea Díaz‐Pérez   +3 more
wiley   +1 more source

Psychotic depression associated with Graves' disease: A case report on treatment prioritization

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 4, December 2026.
Abstract Background Graves' disease can be accompanied by psychiatric symptoms, including affective and psychotic manifestations. When a well‐defined psychiatric syndrome occurs concurrently with a medical illness, determining whether it is directly attributable to the medical condition or represents an independent psychiatric disorder precipitated by ...
Ayumu Kocha   +7 more
wiley   +1 more source

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