Results 21 to 30 of about 244,647 (190)

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source

Hyperbranched poly‐L‐lysine surface‐engineered bioprosthetic heart valves with anti‐calcification, anti‐infection, and durability

BMEMat, EarlyView.
The challenges of bioprosthetic heart valves (BHV) with respect to calcification, infection, and poor durability are tackled by surface engineering of hyperbranched poly‐L‐lysine (HBPL), providing a translational solution to improve long‐term valve performance.
Pai Peng, Dongchao Qiu, Yongyuan Kang, Qiaoxuan Wang, Xuelong Wang, Boyana Parvanova, Miroslav Karabaliev, Changyou Gao   +7 more
wiley   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Hypertensive target organ damage in Ghanaian civil servants with hypertension. [PDF]

, 2009
BACKGROUND: Low levels of detection, treatment and control of hypertension have repeatedly been reported from sub Saharan Africa, potentially increasing the likelihood of target organ damage.
David A Leon, Leon, David A, Smeeth, Liam, Juliet Addo, Smeeth Liam, Addo Juliet, Addo, Juliet, Liam Smeeth, Leon David A.   +8 more
core   +1 more source

Sublingual valsartan in hypertensive urgency

, 2001
The objective of this study was to assess the effect of sublingual valsartan in a group of patients with hypertensive urgency. Forty-one patients with hypertensive urgency and systolic blood pressure >200 mmHg, diastolic blood pressure >100 mmHg were ...
Nazan Alparslan, Saime Paydaş, Güven Kuvandık, Yüksel Gökel   +3 more
core   +1 more source

“Thinking Out Loud” and “Pivoting on the Fly”—An Empirical Review and Critical Incident Study of How Physicians Engage in Incidental Learning Amidst Complexity

Human Resource Development Quarterly, EarlyView.
ABSTRACT This study explores incidental learning among physicians navigating uncertainty during the COVID‐19 pandemic. Using a constructivist research design, we conducted a literature review of 13 empirical studies on incidental learning in complexity and analyzed critical incident interviews with 12 emergency medicine and intensive care physicians ...
Henriette Lundgren, Karen E. Watkins, Victoria J. Marsick, Dimitrios Papanagnou, Urvashi Vaid   +4 more
wiley   +1 more source

Risk factors for intrapartum stillbirth and the survival probabilities of fetuses among pregnant women with complications: Secondary analysis of data from a multicenter prospective cohort study in India

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To identify the risk factors for intrapartum stillbirth and examine whether these are different from that of antepartum stillbirth, and investigate the survival probabilities of fetuses by gestational age in high‐risk pregnancies. Methods We conducted a secondary data analysis of a hospital‐based cohort study from India, including ...
Yebeen Ysabelle Boo, Saswati S. Choudhury, Farzana Zahir, Gitanjali Deka, Amrit K. Bora, Shakuntala Chhabra, Pramod Kumar, Pranabika Mahanta, Bina Minz, Anjali Rani, Sereesha Rao, Indrani Roy, Carolin Solomi V., Ashok Verma, Swapna Kakoty, Omesh Kumar Bharti, Rupanjali Deka, Charles Opondo, Tuck Seng Cheng, Jennifer J. Kurinczuk, Manisha Nair, on behalf of the MaatHRI collaborators   +21 more
wiley   +1 more source

Posttraumatic stress disorder 2 months after induced vaginal delivery: A multicenter prospective study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objectives An increased risk of postpartum posttraumatic stress disorder (PTSD) has been reported in women who had labor induced. Knowledge of childbirth‐related PTSD in this context remain poorly documented. Our aim was to assess the PTSD prevalence and identify characteristics associated with it after induced vaginal delivery at or near term.
Alizée Froeliger, Catherine Deneux‐Tharaux, Lola Loussert, Anne Laure Sutter‐Dallay, Hugo Madar, Loïc Sentilhes, on behalf of the Tranexamic Acid for Preventing Postpartum Hemorrhage Following a Vaginal Delivery (TRAAP) study group, Loïc Sentilhes, Norbert Winer, Elie Azria, Marie Victoire Sénat, Camille Le Ray, Delphine Vardon, Franck Perrotin, Raoul Desbrière, Florent Fuchs, Gilles Kayem, Guillaume Ducarme, Muriel Doret‐Dion, Cyril Huissoud, Caroline Bohec, Philippe Deruelle, Astrid Darsonval, Jean‐Marie Chrétien, Aurélien Seco, Valérie Daniel, Catherine Deneux‐Tharaux   +26 more
wiley   +1 more source