Results 111 to 120 of about 40,180 (167)

Hyperthermia-induced seizures: Development of hyperthermia-prone and hyperthermia-resistant rats

Epilepsy Research, 2013
Febrile seizures (FS), as a multifactorial and genetic disease, are the most common type of convulsive event in infants and young children. Their genetic basis, however, remains elusive. To investigate the genetic mechanisms involved in FS and to identify novel susceptibility genes, we developed two new strains of rats that are hyperthermia-prone (HP ...
Jian, Xu, Yuanteng, Fan, Liang, Li, Yanyan, Qiu, Zhongcheng, Wang, Song, Han, Jun, Yin, Wanhong, Liu, Biwen, Peng, Xiaohua, He   +9 more
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Vigilance Under Induced Hyperthermia

Ergonomics, 1972
Abstract Twelve highly practised subjects were tested in an ambient environment of 103°F (DB), 93°F (WB) on a 1-hour task of visual vigilance, after having performed, in the same environment, physical work which produced an ultimate rise in body-temperature of approximately 0·.4°F for every ten minutes of continuous activity. The vigilance test was not
W P, Colquhoun, R F, Goldman
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Pipradrol-induced hyperthermia in the rabbit

Pharmacological Research Communications, 1984
Intravenous administration of the stimulant drug pipradrol evoked a dose-dependent hyperthermic response in rabbits. This drug effect was significantly reduced by pretreatment with chlorpromazine, phenoxybenzamine, intravenous BE-2254 or intracerebroventricular BE-2254.
S F, Small, R M, Quock, M H, Malone
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Hyperthermia-induced pulmonary edema

Journal of Applied Physiology, 1986
The effects of temperature (37–45 degrees C) on pulmonary edema formation and transendothelial albumin clearance were investigated using isolated perfused guinea pig lungs and bovine pulmonary arterial endothelial cells grown to confluency on a gelatinized membrane.
K Y, Mustafa, W M, Selig, K E, Burhop, F L, Minnear, A B, Malik   +4 more
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“On‐Off”–induced lethal hyperthermia

Movement Disorders, 1989
AbstractNeuroleptic malignant syndrome (NMS) is being increasingly recognized as a potential complication of neuroleptic therapy. Similar hyperthermic episodes have also been described in other settings of adrupt cessation of dopaminergic stimulation such as levodopa withdrawal. We report a fatal NMS‐like episode occurring as a complication of an “off”
R F, Pfeiffer, E L, Sucha
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Atracurium during induced hyperthermia

Journal of Anesthesia, 2009
During hyperthermic intraperitoneal chemotherapy (HIPEC), we observed a partial recovery from neuromuscular block in a hyperthermic patient after hours of monitored adequate surgical relaxation and continuous infusion of atracurium during normothermia. This recovery is indicative of the higher clearance of atracurium during hyperthermia.
Gersten, Jonker, Leo J, Hoogenboom, Bert, van Ramshorst, Peter, Bruins   +3 more
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Hyperthermia-induced drug targeting

Expert Opinion on Drug Delivery, 2013
Specific delivery of a drug to a target site is a major goal of drug delivery research. Using temperature-sensitive liposomes (TSLs) is one way to achieve this; the liposome acts as a protective carrier, allowing increased drug to flow through the bloodstream by minimizing clearance and non-specific uptake.
Jonathan P, May, Shyh-Dar, Li
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Hyperthermia Induces Apoptosis in Thymocytes

Radiation Research, 1991
Mild hyperthermia (43 degrees C for 1 h) induces extensive double-stranded DNA fragmentation and, at a later time, cell death in murine thymocytes. The cleavage of DNA into oligonucleosome-sized fragments resembles that observed in examples of apoptosis including radiation-induced death of thymocytes.
K S, Sellins, J J, Cohen
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Stress-Induced Hyperthermia in the Mouse

2009
In anxiety research, the search for a model with sufficient clinical predictive validity to support the translation of animal studies on anxiolytic drugs to clinical research is challenging. The stress-induced hyperthermia (SIH) model studies the body temperature increase in response to acute stress which is mediated by the autonomic nervous system ...
Vinkers, Christiaan H, Van Oorschot, Ruud, Olivier, Berend, Groenink, Lucianne   +3 more
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Management of drug-induced hyperthermia>

Current Opinion in Pediatrics, 2004
To review the current literature describing drug-induced hyperthermia and its treatment. Specifically, five syndromes will be discussed: malignant hyperthermia, neuroleptic malignant syndrome, anticholinergic poisoning, sympathomimetic poisoning, and serotonin syndrome.The most recent findings in the literature are the recognition of previously ...
Lindara L, Halloran, David W, Bernard
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