Results 131 to 140 of about 3,374,250 (258)

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Transcriptomic analysis reveals distinct adaptive molecular mechanism in the hippocampal CA3 from rats susceptible or not-susceptible to hyperthermia-induced seizures. [PDF]

Sci Rep, 2023
Bando SY, Bertonha FB, Menezes PHN, Takahara AK, Khaled NA, Santos P, S Junqueira M, Cesar RM, Moreira-Filho CA.   +8 more
europepmc   +1 more source

Interstitial Radiofrequency Hyperthermia for Brain Tumors : Preliminary Laboratory Studies and Clinical Application [PDF]

, 1993
An interstitial radiofrequency (RF) hyperthermia system for brain tumor was evaluated in cranial phantoms and cat brains. An intracranial RF applicator and thermocouple microprobes were emplaced in the brain and a headband-type flexible extracranial ...
Mori, Kazuo, Tokunaga, Yoshiharu, Koga, Hiroaki   +2 more
core  

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

BMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang, Zhuomin Wang, Zhenhua Jin, Ahmed H. Ghonaim, Hengcheng Zhang, Xinyu You, Jinzhuo Ning, Jiaqing Cao, Yang Liu   +8 more
wiley   +1 more source

Hyperthermia-Induced In Situ Drug Amorphization by Superparamagnetic Nanoparticles in Oral Dosage Forms. [PDF]

ACS Appl Mater Interfaces, 2022
Ansari SR, Hempel NJ, Asad S, Svedlindh P, Bergström CAS, Löbmann K, Teleki A.   +6 more
europepmc   +1 more source

Electron compensation‐gated nanomotor for immunomodulation and microenvironment remodeling in bacterial pneumonia therapy

BMEMat, EarlyView.
A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue, Xiaoyu Zhao, Yuqian Wang, Lijin Shi, Qi Shuai   +4 more
wiley   +1 more source

Heterozygous deletion of Gpr55 does not affect a hyperthermia-induced seizure, spontaneous seizures or survival in the Scn1a+/- mouse model of Dravet syndrome. [PDF]

PLoS One, 2023
Anderson LL, Bahceci DA, Hawkins NA, Everett-Morgan D, Banister SD, Kearney JA, Arnold JC.   +6 more
europepmc   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Localized brain stimulation with mild magnetic hyperthermia promotes microglia activity towards reactive and autophagic phenotypes in vivo

Scientific Reports
The principle of magnetic hyperthermia is to generate localized heating on target proteins, cells and tissue that are targeted by magnetic nanoparticles (MNPs) upon stimulation by remotely applied high frequency alternating magnetic field (AMF).
Byeong Tak Jeon, Muhammad Naveed, Matthew Puleo, Woo-Yang Kim, Min-Ho Kim   +4 more
doaj   +1 more source

Combination therapy with radiation and hyperthermia-induced clinical complete response of small cell carcinoma of prostate. [PDF]

IJU Case Rep, 2022
Kawai N, Nagai T, Naiki-Ito A, Iida K, Etani T, Naiki T, Hamamoto S, Okada A, Murai T, Yasui T.   +9 more
europepmc   +1 more source