Results 271 to 280 of about 7,634,819 (349)

Hyperthermia-induced drug targeting

Expert Opinion on Drug Delivery, 2013
Specific delivery of a drug to a target site is a major goal of drug delivery research. Using temperature-sensitive liposomes (TSLs) is one way to achieve this; the liposome acts as a protective carrier, allowing increased drug to flow through the bloodstream by minimizing clearance and non-specific uptake.
Jonathan P, May, Shyh-Dar, Li
openaire   +3 more sources

Stress-induced hyperthermia and hypothermia

Handbook of Clinical Neurology, 2018
Stress affects core body temperature (Tc). Many kinds of stress induce transient, monophasic hyperthermia, which diminishes gradually if the stressor is terminated. Stronger stressors produce a longer-lasting effect. Repeated/chronic stress induces anticipatory hyperthermia, reduces diurnal changes in Tc, or slightly increases Tc throughout the day ...
T. Oka
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Mild Hyperthermia Induced by Hollow Mesoporous Prussian Blue Nanoparticles in Alliance with a Low Concentration of Hydrogen Peroxide Shows Powerful Antibacterial Effect.

Molecular Pharmaceutics, 2022
The emergence of superbacteria as well as the drug resistance of the current bacteria gives rise to worry regarding a bacterial pandemic and also calls for the development of novel ways to combat the bacteria.
Yuting Li, Yun Zhu, Cheng Wang, Yue Shen, Li Liu, Shuwen Zhou, Peng-Fei Cui, Huaanzi Hu, Pengju Jiang, Xinye Ni, Lin Qiu, Jianhao Wang   +11 more
semanticscholar   +1 more source

Extreme hyperthermia-induced arrhythmogenesis

Cardiology in the Young, 2021
AbstractHyperthermia is defined as an elevated body temperature above the normal range due to a failure of heat regulatory mechanisms. In addition to its effects on other organ systems, hyperthermia is associated with profound cardiovascular effects. We report the sentinel case of a 6-year-old girl with structurally and electrically normal heart, who ...
Tripat Kaur, Chenni S. Sriram, Utkarsh Kohli   +2 more
openaire   +2 more sources

Photobiomodulation restores spermatogenesis in the transient scrotal hyperthermia-induced mice.

Life Science, 2020
OBJECTIVE Heat stress shock affects the generation of free radicals and can have a harmful effect on spermatogenesis. Photobiomodulation (PBM) is very effective in andrology for treating male infertility.
Amirhosein Hasani, A. Khosravi, Kimia Rahimi, Azar Afshar, F. F. Fathabadi, A. Raoofi, Pourya Raee, Fakhroddin Aghajanpour, Abbas Aliaghaei, S. Abdi, M. Norouzian, M. Abdollahifar   +11 more
semanticscholar   +1 more source

DRUG-INDUCED HYPERTHERMIA

Critical Care Clinics, 1997
Drug-related causes of hyperthermia can often be overlooked in the setting of elevated body temperature. This article reviews the pathophysiology, presentation, and treatment of several drug-induced hyperthermia syndromes: malignant hyperthermia, neuroleptic malignant syndrome, sympathomimetic poisoning, and anticholinergic toxicity.
T C, Chan, S D, Evans, R F, Clark
openaire   +2 more sources

Hyperthermia-induced seizures: Development of hyperthermia-prone and hyperthermia-resistant rats

Epilepsy Research, 2013
Febrile seizures (FS), as a multifactorial and genetic disease, are the most common type of convulsive event in infants and young children. Their genetic basis, however, remains elusive. To investigate the genetic mechanisms involved in FS and to identify novel susceptibility genes, we developed two new strains of rats that are hyperthermia-prone (HP ...
Jian, Xu, Yuanteng, Fan, Liang, Li, Yanyan, Qiu, Zhongcheng, Wang, Song, Han, Jun, Yin, Wanhong, Liu, Biwen, Peng, Xiaohua, He   +9 more
openaire   +2 more sources

Vigilance Under Induced Hyperthermia

Ergonomics, 1972
Abstract Twelve highly practised subjects were tested in an ambient environment of 103°F (DB), 93°F (WB) on a 1-hour task of visual vigilance, after having performed, in the same environment, physical work which produced an ultimate rise in body-temperature of approximately 0·.4°F for every ten minutes of continuous activity. The vigilance test was not
W P, Colquhoun, R F, Goldman
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Pipradrol-induced hyperthermia in the rabbit

Pharmacological Research Communications, 1984
Intravenous administration of the stimulant drug pipradrol evoked a dose-dependent hyperthermic response in rabbits. This drug effect was significantly reduced by pretreatment with chlorpromazine, phenoxybenzamine, intravenous BE-2254 or intracerebroventricular BE-2254.
S F, Small, R M, Quock, M H, Malone
openaire   +2 more sources