Results 251 to 260 of about 7,634,819 (349)

Heat Stress Triggers Nuclear Invagination and Spatial Compartmentalization of Protein Metabolism

open access: yesCell Proliferation, EarlyView.
Cells adapt heat stress to shape a nuclear invagination region function as “protein metabolism hotspots”, where both protein production and degradation are enhanced. ABSTRACT Heat stress is a common challenge for cells, causing multiple types of cellular damage while triggering complex stress responses, including the highly conserved mechanism known as
Zhi‐Hao Zhang   +11 more
wiley   +1 more source

From Cold to Hot: Nanozyme‐Based Strategies for Reprogramming the Tumour Immunoenvironment

open access: yesCell Proliferation, EarlyView.
Nanozymes, with multi‐enzyme catalytic activities, reprogram the immunosuppressive tumour microenvironment by inducing immunogenic cell death, relieving hypoxia, and depleting antioxidants, effectively converting immunologically “cold” tumours into “hot” ones to boost cancer immunotherapy efficacy.
Yue Wang   +9 more
wiley   +1 more source

Seizures in children with Dravet syndrome in extreme heat: A qualitative study of parental perspectives

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Perspectives of parents of children with Dravet syndrome indicate that extreme heat and high temperatures exacerbate epileptic seizures, introduce new seizure triggers, and require the adoption of specific seizure‑management strategies. Abstract Aim To describe parental perspectives on how heatwaves and high ambient temperatures influence seizure ...
Angel Aledo‐Serrano   +8 more
wiley   +1 more source

Response to equine cardiac adverse events during sports

open access: yesEquine Veterinary Education, EarlyView.
Summary Cardiac adverse events and sudden death are a feared scenario for equine veterinarians, with serious consequences for animal health, riders' safety and the social licence to operate equestrian sports. The response to equine cardiac adverse events (CAEs) during sports is poorly defined.
C. Navas de Solis   +9 more
wiley   +1 more source

Paroxysmal sympathetic hyperactivity secondary to hypoglycemic encephalopathy: A case report

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT A 48‐year‐old male was admitted to our hospital due to a hypoglycemic coma. Although his blood glucose level was increased after glucose administration, his impaired consciousness persisted. Magnetic resonance imaging indicated hypoglycemic encephalopathy.
Yushi Kohzuki   +5 more
wiley   +1 more source

Size of Subcortical Band Heterotopia Influences the Susceptibility to Hyperthermia-Induced Seizures in a Rat Model. [PDF]

open access: yesFront Cell Neurosci, 2019
Moustaki K   +5 more
europepmc   +1 more source

Pejerrey (Odontesthes bonariensis) Under Siege: Main Infectious Diseases and Their Role in Aquaculture and Wild Populations Amidst Environmental Change

open access: yesJournal of Fish Diseases, Volume 48, Issue 4, April 2025.
ABSTRACT The pejerrey (Odontesthes bonariensis) is a key species for recreational and commercial fisheries in Argentina and holds significant aquaculture potential. It has been introduced to various countries worldwide, including Japan, where intensive aquaculture has developed.
Aarón Torres‐Martínez   +4 more
wiley   +1 more source

Pharmacokinetics of a Single Subcutaneous Extended‐Release Buprenorphine (Ethiqa XR) in Healthy Beagles

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT This study evaluated the pharmacokinetics of an extended‐release buprenorphine formulation (Ethiqa XR) in dogs and explored potential sex differences. Twelve healthy intact beagles (6 males and 6 females) received a single subcutaneous injection of Ethiqa XR (0.2 mg/kg).
Kornelia Tiffinger   +5 more
wiley   +1 more source

Far‐infrared irradiation attenuates platelet‐derived growth factor‐stimulated vascular smooth muscle cell migration through protein phosphatase 2A‐mediated Akt inhibition

open access: yesPhotochemistry and Photobiology, EarlyView.
FIR irradiation enhances the physical association between Akt and PP2Ac in VSMCs, independent of the hyperthermal effect of FIR rays. The increased binding between Akt and PP2Ac induced by FIR irradiation facilitates the dephosphorylation of Akt at Ser473.
Na‐Young Lee   +5 more
wiley   +1 more source

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