Peptide‐based responsive molecular fluorescent probes for precision oncology
Responsive Materials, EarlyView.Peptide‐based responsive fluorescent probes have emerged as adaptive functional materials for precision tumor theranostics, combining tumor‐selective recognition, programmable stimulus responsiveness, and modular tunability. They enable high‐contrast imaging, intraoperative guidance, real‐time monitoring, and multimodal applications, while next ...
Xing Wang +6 more
wiley +1 more source
Small, EarlyView.A biomimetic Au/Ag@HMON‐NLG@CCM nanotheranostic is engineered for tumor microenvironment‐responsive NIR‐II ratiometric photoacoustic imaging and immune‐photothermal therapy. The integration of hyperthermia‐triggered immunogenic cell death with IDO‐blockade‐mediated metabolic remodeling promotes dendritic cell maturation and T‐cell activation.
Xin Li +9 more
wiley +1 more source
Ultrastructural Analysis of the Large Neuronal Perikarya in an Injured Dentate Nucleus Using an Experimental Model of Hyperthermia-Induced Convulsions: The First Qualitative and Quantitative Study. [PDF]
J Clin MedŁotowska JM +4 more
europepmc +1 more source
Smart Molecules, EarlyView.To advance precision cancer therapy, we engineered ER‐BDP NPs, a self‐assembled nanomedicine designed for selective ER localization. By integrating organelle targeting with localized laser activation, this agent mediates precision‐guided tumor destruction in vitro and in vivo while reducing off‐target effects, effectively balancing therapeutic efficacy
Shaoyang Shi +8 more
wiley +1 more source
Small Methods, EarlyView.We propose mild‐MHT protocol for the quick internalization of magnetic nanoparticles (MNPs) by immune cells. The heat induced by MNPs under alternating magnetic field stimulate MNPs diffusion and cell membrane invagination, accelerating the cellular internalization of MNPs. ABSTRACT Immune cell therapies show promise in hematologic malignancies and are
Giulia E. P. Nucci +8 more
wiley +1 more source
Hyperthermia-Induced Controlled Local Anesthesia Administration Using Gelatin-Coated Iron-Gold Alloy Nanoparticles. [PDF]
Pharmaceutics, 2020 Ting CK +6 more
europepmc +1 more source
Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges
The Chemical Record, EarlyView.Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
wiley +1 more source
Diagnosis and rescue of malignant hyperthermia induced by anesthesia during radical surgery in a cervical cancer patient using the National Remote Emergency System: A case report. [PDF]
Medicine (Baltimore)Xiao Y, Yu R, Gu J.
europepmc +1 more source
The Chemical Record, EarlyView.Valve metal oxide nanostructures such as TiO2, Ta2O5, Nb2O5, ZrO2, and HfO2 are emerging as versatile biomedical platforms due to their tunable surface properties, exceptional stability, and inherent biocompatibility. This review highlights their synthesis, physicochemical properties, and biological interactions, addressing their roles in advanced ...
Nina Kummer +11 more
wiley +1 more source
Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity
VIEW, EarlyView.Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin +3 more
wiley +1 more source