Results 241 to 250 of about 7,634,819 (349)

Cumulative heatwave stress disrupts thermal homeostasis and plumage structure in a Mediterranean passerine

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Heatwaves are becoming increasingly frequent across the Mediterranean and pose critical challenges for small passerines, yet the physiological and morphological limits to their resilience remain poorly understood.
Erick González‐Medina   +6 more
wiley   +1 more source

A call for action: Closing the evidence gap in management of stimulant‐induced psychosis

open access: yesAddiction, EarlyView.
Abstract Background Stimulant‐induced psychosis (StIP) is emerging as one of most pressing health challenges. Over the past two decades, stimulant‐related harms and psychiatric care demands have risen sharply. Individuals with StIP often present with severe agitation and high suicide risk, and up to half progress to chronic psychotic illness within two
Anne Bouthillier   +3 more
wiley   +1 more source

Labour epidural analgesia and early childhood behavioural outcomes: the moderating role of maternal mental health and pro‐inflammatory cytokines

open access: yesAnaesthesia, EarlyView.
Summary Introduction Labour epidural analgesia is the most effective method for intrapartum pain relief and is associated with improved maternal outcomes. However, concerns have been raised regarding potential associations between labour epidural analgesia and adverse psycho‐emotional outcomes in children. Evidence from large epidemiological studies is
Sana Asif   +6 more
wiley   +1 more source

Safety pharmacology of acute mescaline administration in healthy participants

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber   +4 more
wiley   +1 more source

[Induced hyperthermia].

open access: yesKokubyo Gakkai zasshi. The Journal of the Stomatological Society, Japan, 1986
openaire   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Toll‐like receptor 4 mediates lipopolysaccharide‐induced emesis

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Lipopolysaccharide (LPS) induces inflammation and sepsis through Toll‐like receptor 4 (TLR4) activation. Common laboratory animals do not exhibit emesis, but administration of LPS in piglets, cats, and dogs induces emesis via peripheral mechanisms.
Luping Liu   +5 more
wiley   +1 more source

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