Results 101 to 110 of about 141,643 (222)

Intelligent Thermo‐Self‐Limited Magnetothermia with Heat‐Triggered TERT Silencing for Precision Synergetic Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Telomerase reverse transcriptase (TERT) mRNA induces DNA self‐assembly in cancer cells, boosting the nanoplatform's magnetothermal properties. This magnetothermia then activates the Hsp70 promoter, initiating siRNA synthesis to silence the TERT gene, enhancing cancer treatment.
Liang Zhang   +9 more
wiley   +1 more source

Hyperthermia as a factor of secondary brain damage in traumatic brain injury

open access: yesМедицина неотложных состояний
The development of hyperthermia (≥38.3 °C) in severe traumatic brain injury (TBI) is associated with increased levels of disability and mortality, since it critically affects the development of secondary brain damage.
D.V. Olenyuk, A.V. Tsarev
doaj   +1 more source

Localized delivery of therapeutic doxorubicin dose across the canine blood–brain barrier with hyperthermia and temperature sensitive liposomes

open access: yesDrug Delivery, 2018
Most drugs cannot penetrate the blood–brain barrier (BBB), greatly limiting the use of anti-cancer agents for brain cancer therapy. Temperature sensitive liposomes (TSL) are nanoparticles that rapidly release the contained drug in response to ...
Amy Lee Bredlau   +8 more
doaj   +1 more source

Boosting Photo‐Pyroelectric Effect via Tunable Polarization and Interfacial Defect Engineering

open access: yesAdvanced Science, EarlyView.
This study reports Ba(Ti0.85Zr0.15)O3 nanocatalysts with enhanced polarization and oxygen‐vacancy‐rich interfaces for efficient NIR‐II photo‐pyroelectric therapy. Zr doping boosts the pyroelectric coefficient and accelerates polarization switching, while oxygen vacancies improve photothermal conversion and surface reactivity.
Yanli Huang   +13 more
wiley   +1 more source

A Photothermal Transducer Regulates Transmembrane Calcium Flow for Synergistic Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
Upon NIR irradiation at 808 nm, the activity of TRPV4 was inhibited by M2M@BPSC, which led to reduced calcium influx, mitochondrial protection, and, importantly, the transcriptional activation of the STAT6‐EGR2 pathway. The improved macrophage function indirectly readjusts the equilibrium between C‐ECM and F‐ECM to reconstruct a suitable ...
Chenqi Yu   +11 more
wiley   +1 more source

Hyperthermic potentiation of cisplatin by magnetic nanoparticle heaters is correlated with an increase in cell membrane fluidity

open access: yesInternational Journal of Nanomedicine, 2013
Merlis P Alvarez-Berríos, Amalchi Castillo, Janet Mendéz, Orlando Soto, Carlos Rinaldi, Madeline Torres-LugoDepartment of Chemical Engineering, University of Puerto Rico, Mayagüez, Puerto RicoAbstract: Magnetic fluid ...
Alvarez-Berrios MP   +5 more
doaj  

Hysteresis in a magnetic bead and its applications

open access: yes, 2012
We study hysteresis in a micron-sized bead: a non-magnetic matrix embedded with super- paramagnetic nanoparticles. These hold tremendous promise in therapeutic applications as heat generating machines. The theoretical formulation uses a mean-field theory
Dattagupta S.   +4 more
core   +1 more source

Focal Spot, Spring 1987 [PDF]

open access: yes, 1987
https://digitalcommons.wustl.edu/focal_spot_archives/1045/thumbnail ...

core   +1 more source

ROLE OF LOCAL HYPERTHERMIA IN COMBINED MODALITY TREATMENT OF SOFT TISSUE SARCOMAS

open access: yesСибирский онкологический журнал, 2016
The review aimed to assess the role of local hyperthermia in combined modality treatment of soft tissue sarcoma. The recent randomized trials have shown significant benefits from local hyperthermia in patients with soft tissue sarcoma. When combined with
Zh. A. Startseva   +8 more
doaj  

The Effect of Hyperthermia on the Gene Expression of MDR1 and MRP4 Drug Efflux in Colorectal Cancer Cells

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2020
BACKGROUND AND OBJECTIVE: Hyperthermia has been reported as a new and adjunctive treatment of cancer in inhibiting DNA repair, increasing radiation sensitivity of cancer stem cells, increasing the sensitivity of drug-resistant cancer cells, and ...
Z Ghorbani   +4 more
doaj  

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