Results 161 to 170 of about 220,987 (396)
Advanced Science, EarlyView.A single‐atom nanozyme‐based multifunctional nanoplatform synergizes bacterial targeting with a NIR‐II responsive therapeutic cascade for effective diabetic wound management. This nanoplatform enhances biofilm destruction through photothermal‐augmented biocatalysis while simultaneously activating endothelial cells by delivering nitric oxide to promote ...
Junyang Chen +7 more
wiley +1 more source
Advanced Science, EarlyView.Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera +12 more
wiley +1 more source
Integrating Metabolic Modulation and Nanomedicine for Cancer Immunotherapy
Advanced Science, EarlyView.Metabolic rewiring in cancer is mapped across glucose, amino acid, lipid, nucleotide, and mitochondrial pathways, with emphasis on immune regulation. The review integrates mechanisms linking these pathways to tumor progression and therapy resistance, and profiles nanomaterial platforms that both deliver therapeutics and actively reprogram ...
Xiaosu Zhou +7 more
wiley +1 more source
Advanced Science, EarlyView.This review highlights the synthesis and applications of magnetized cells (MCs) and magnetized scaffolds (MSs) in advancing bone tissue engineering strategies. It further demonstrates how magnetic particles (MPs) improve scaffold properties and how external magnetic fields enhance mesenchymal stem cell adhesion, proliferation, and osteogenic ...
Elio Cinar SanSegundo +3 more
wiley +1 more source
Advanced Science, EarlyView.Temperature is a crucial fundamental physical parameter involved in all life activities. An AIEgen‐based mixed lanthanide MOF is synthesized. In the physiological temperature range, this MOF shows superior performance. To achieve the detection of intracellular temperature, a nanoscale mixed LnMOF is synthesized and further modified to enable the visual
Zhijia Li +10 more
wiley +1 more source
Advanced Science, EarlyView.In this study, an “all‐in‐one” engineered anaerobic bacterial system (PDAEcN/COS) is developed for the treatment of immunologically “cold” TNBC. This nanoplatform is capable of colonizing tumor cell surfaces and implementing “self‐blocking” of immune checkpoints, while simultaneously suppressing tumor cells' “don't eat me” signals and delivering “eat ...
Xuanxiang Zhai +6 more
wiley +1 more source
Advanced Science, EarlyView.The cRGD‐ILD molecular probe integrates clinically available components: a cRGD peptide (integrin αvβ3 targeting), ICG (for fluorescence/photoacoustic imaging and phototherapy), and Gd‐DTPA (MRI contrast). Utilizing small size and receptor targeting, it achieves selective lesion accumulation.
Qiyu Zhong +9 more
wiley +1 more source
Advanced Science, EarlyView.An electro–magnetic–porous multigradient nanofibrous electromagnetic interference (EMI) membrane is fabricated via shear‐induced in situ fibrillation and layer‐by‐layer assembly. Leveraging a multigradient‐induced “impedance matching–polarization–reabsorption” synergistic mechanism, the membrane achieves absorption‐dominated high‐efficiency EMI ...
Runze Shao +5 more
wiley +1 more source