Results 41 to 50 of about 41,010 (268)

Hypertonic saline in the treatment of patients with cystic fibrosis in Russian Federation

open access: yesМедицинский совет, 2021
Introduction. Mucolytic therapy is basic in the treatment of patients with cystic fibrosis (CF). Currently, inhalation of hypertonic saline (HS) of NaCl is recommended for the treatment of CF patients.The aim of the study was to investigate the ...
E. I. Kondatyeva   +2 more
doaj   +1 more source

A systematic review of neuroprotective strategies after cardiac arrest: from bench to bedside (Part I - Protection via specific pathways). [PDF]

open access: yes, 2014
Neurocognitive deficits are a major source of morbidity in survivors of cardiac arrest. Treatment options that could be implemented either during cardiopulmonary resuscitation or after return of spontaneous circulation to improve these neurological ...
Applegate, Patricia M   +5 more
core   +2 more sources

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

Presystemic influences on thirst, salt appetite, and vasopressin secretion in the hypovolemic rat [PDF]

open access: yes, 2006
Recent studies have shown that when dehydrated rats are given access to water or various concentrations of saline solution, they consume the same volume of fluid in an initial drinking bout (Hoffmann et al., 2006). Furthermore, there was a close relation
Smith, Carrie Alane
core  

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Successful Management of Refractory Chylothorax in Preterm Infants Using Hypertonic Glucose Pleurodesis [PDF]

open access: yesNeonatal Medicine
Neonatal chylothorax is a potentially fatal respiratory condition caused by a congenital or traumatic etiology. Conventional therapies, such as fasting, total parenteral nutrition, and intravenous octreotide, are generally successful in such cases ...
Young Seok Do   +9 more
doaj   +1 more source

Rationale and study design of intravenous loop diuretic administration in acute heart failure. DIUR-AHF [PDF]

open access: yes, 2017
Aims: Although loop diuretics are the most commonly used drugs in acute heart failure (AHF) treatment, their short-term and long-term effects are relatively unknown.
Di Somma, Salvatore   +5 more
core   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez   +10 more
wiley   +1 more source

Efficacy of Nasal Irrigation with Isotonic and Hypertonic Solutions after Endoscopic Sinus Surgery for Chronic Rhinosinusitis with Nasal Polyposis

open access: yesActa Clinica Croatica
Endoscopic sinus surgery (ESS) is often involved in the treatment of patients with chronic rhinosinusitis with nasal polyposis (CRSwNP). Nasal irrigation after ESS is recommended to improve healing and nasal symptoms in these patients.
Ana Penezić   +6 more
doaj   +1 more source

The cost-effectiveness of hypertonic saline inhalations for infant bronchiolitis

open access: yesBMC Health Services Research, 2020
Background Pharmacological treatment for bronchiolitis is primarily supportive because bronchodilators, steroids, and antibiotics, show little benefit.
Jefferson Antonio Buendía   +1 more
doaj   +1 more source

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