Results 131 to 140 of about 13,059 (242)

CLRN1 Variants in Müller Cells Cause Mitochondrial Dysfunction in USH3A Retinal Organoids

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
We generated retinal organoids from a patient with USH3A and performed single‐cell RNA sequencing. CLRN1 was specifically expressed in Müller cells, where its variants led to mitochondrial dysfunction and photoreceptor degeneration. ABSTRACT Background Usher syndrome 3A (USH3A), caused by mutations in the CLRN1 gene, leads to retinitis pigmentosa and ...
Rui Zhang, Xinbo Ji, Han Yu, Jingwen Xu, Yu Wang, Ping Sun, Yingxin Wang, Yao Tang, Zexin Zhan, Yichang Jiao, Didi Shan, Pengfei Lin, Dong‐dong Wang, Yuying Zhao, Xianyang Liu, Chuanzhu Yan, Jianqiao Li, Mingfeng Li, Fuchen Liu, Shengping Hou   +19 more
wiley   +1 more source

The endoplasmic reticulum displays high polarity with low protein aggregation in human cells. [PDF]

Commun Biol
Hu X, Chen J, Liu P, Zhang H, Liu Y, Zhang X, Wang L.   +6 more
europepmc   +1 more source

The behaviour of frog muscle in hypertonic solutions

The Journal of Physiology, 1958
openaire   +3 more sources

Real‐world‐data for phenotypes and genotypes of rare monogenic genetic epilepsies and genes of uncertain significance for epilepsy

Epilepsia Open, Volume 11, Issue 4, Page 1184-1199, August 2026.
Abstract Objectives The objectives of this study were to develop a real‐world‐data (RWD) database for patients with epilepsy to provide further real‐world‐evidence (RWE) for monogenic genetic epilepsies; to assess the usefulness of a diagnostic algorithm in epilepsy; and to examine protein 3D structures using in silico tools to predict variant ...
Haley Morris, Elizabeth Mathew, Shalini Bahl, Marta Villa‐Lopez, Saadet Mercimek‐Andrews   +4 more
wiley   +1 more source

β-Arrestin-2 Regulates Sodium Taste Processing. [PDF]

Hypertension
Grobe CC, Hamilton AJ, Treesukosol Y, Grobe JL, Segar JL, Sigmund CD.   +5 more
europepmc   +1 more source

Ketogenic diet therapy for children with super‐refractory status epilepticus in intensive care: International clinical practice recommendations

Epilepsia Open, Volume 11, Issue 4, Page 1354-1369, August 2026.
Abstract Objective We aimed to create practical recommendations to support healthcare teams starting ketogenic diet therapy (KDT) for children with super‐refractory status epilepticus in intensive care settings. Methods A literature review was conducted to extract published data on patient selection, diet prescription, diet initiation, monitoring, fine‐
Robyn Blackford, Victoria J. Whiteley, Isobel Hardy, Marisa Armeno, Tessa Bollard, J. Helen Cross, Christin Eltze, Susan George, Charlotte Howard, A. Laura Nijstad, Erin Talzzia, Chris Paget, Samiran Ray, Zoe Simpson, Elizabeth Song‐Pozderac, Agnieszka Szmurlo, Charlene Tan‐Smith, Lisa Vanatta, Elles van der Louw, Natasha E. Schoeler, on behalf of the Ketogenic Dietitians Research Network   +20 more
wiley   +1 more source

Effects of <i>peri</i>-arrest hypertonic/hyperoncotic fluid treatment on clinical outcomes in non-trauma-related resuscitation - A scoping review. [PDF]

Resusc Plus
Akbas S, Castellucci C, Haresleb C, Kaserer A, Spahn DR, Breckwoldt J.   +5 more
europepmc   +1 more source

The Renal Function of the Wild Rodent Cerradomys goytaca Reveals Adaptations in the Mechanisms of Urinary Concentration and Solute Excretion

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 7, Page 772-784, August 2026.
Renal adaptations of Cerradomys goytaca associated with survival in its natural habitat. Graphical Abstract of the main renal physiological characteristics identified in C. goytaca. This species exhibits an increased kidney mass index, elevated urine osmolality, and enhanced tubular water reabsorption, indicating a higher capacity for water ...
Luzia Agusta Valeriano‐Monici, Carolina de Augusta Barros Silva, Gustavo de Castro Nascimento, Lana Soares Sales, Carlos de Alberto Souza Filho, Edgar Mendes Souza Wan Der Maas Rosa, Patrick Gabriel Alencar dos Santos, Eulogio de Carlos Queiroz Carvalho, Jones Bernardes Graceli, Pablo Rodrigues Gonçalves, Jackson de Souza‐Menezes   +10 more
wiley   +1 more source

Sodium bicarbonate application for the treatment of acute metabolic acidosis: what we know and what we still don't know. [PDF]

Intensive Care Med
von Groote T, Langer T, Brunoni B.
europepmc   +1 more source

HYPERTONIC SOLUTIONS IN MASSIVE HAEMORRHAGE

British Journal of Anaesthesia, 1993
J. BRIMACOMBE, A. BERRRY
openaire   +1 more source