Results 31 to 40 of about 14,260 (269)

Hypertonic Solution in Severe COVID-19 Patient: A Potential Adjuvant Therapy

Frontiers in Medicine, 2022
Coronavirus disease 2019 (COVID-19) features hyper-inflammation, cytokine storm, neutrophil function changes, and sodium chloride (NaCl) homeostasis disruption, while the treatment with NaCl hypertonic solutions (HS) controls electrolytic body ...
Matheus Gennari-Felipe, Leandro Borges, Alexandre Dermargos, Eleine Weimann, Rui Curi, Rui Curi, Tania Cristina Pithon-Curi, Elaine Hatanaka   +7 more
doaj   +1 more source

Sobre os efeitos vasomotôres exercidos pela agua distilada e pelas soluções anisotonicas de clorêto de sodio Vaso-motricity induced by distilled water and anisotonic salt solutions

Memorias do Instituto Oswaldo Cruz, 1939
The writer reports experiments done with distilled water and hypotonic and hypertonic salt solutions of definite osmotic concentrations. The experiments were performed according to the Laewen-Trendelenburg technic using the vascular system of the frog's ...
Antonio Augusto Xavier
doaj   +1 more source

Hypertonic Saline Suppresses NADPH Oxidase-Dependent Neutrophil Extracellular Trap Formation and Promotes Apoptosis

Frontiers in Immunology, 2018
Tonicity of saline (NaCl) is important in regulating cellular functions and homeostasis. Hypertonic saline is administered to treat many inflammatory diseases, including cystic fibrosis.
Ajantha Nadesalingam, Jacky H. K. Chen, Armin Farahvash, Armin Farahvash, Meraj A. Khan, Meraj A. Khan   +5 more
doaj   +1 more source

Selective Nitrate Transmembrane Transport Through Adaptive Weak C─H Bonding Cyanostilbene Water Channels

Angewandte Chemie, EarlyView.
Here we demonstrate that weak HB CH donor cyanostilbenes promote water/ion transport through their ability to form less‐ordered transient water channels within the lipid bilayer with increased water permeability and NO3−/ Cl− selectivity. ABSTRACT Transmembrane water transport strongly depends on how dynamic, translocating water clusters are stabilized
Ioan Stroia, Dan‐Dan Su, Yuhao Li, Niculina Hadade, Ion Grosu, Arie van der Lee, Mihail Barboiu   +6 more
wiley   +2 more sources

No increase in small-solute transport in peritoneal dialysis patients treated without hypertonic glucose for fifty-four months

BMC Nephrology, 2017
Background Glucose is widely used as an osmotic agent in peritoneal dialysis (PD), but exerts untoward effects on the peritoneum. The potential protective effect of a reduced exposure to hypertonic glucose has never been investigated.
Dominique Pagniez, Alain Duhamel, Eric Boulanger, Celia Lessore de Sainte Foy, Jean-Baptiste Beuscart   +4 more
doaj   +1 more source

Comparison of the in vitro effects of saline, hypertonic hydroxyethyl starch, hypertonic saline, and two forms of hydroxyethyl starch on whole blood coagulation and platelet function in dogs.

, 2015
OBJECTIVE To compare the in vitro effects of hypertonic solutions and colloids to saline on coagulation in dogs. DESIGN In vitro experimental study. SETTING Veterinary teaching hospital.
Howard, J., Adamik, Katja, Francey, Thierry, Wurlod, Virginie A, Schweighauser, Ariane   +4 more
core   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Administration of Hypertonic Solutions for Hemorrhagic Shock

, 2017
BACKGROUND: Several clinical trials on hypertonic fluid administration have been completed, but the results have been inconclusive. The objective of this study is to summarize current evidence for treating hypovolemic patients with hypertonic solutions ...
Lee, Meng Tse Gabriel, Meng-Che Wu, Tin-Yun Liao, Shyr-Chyr Chen, Liao, Tin Yun, Chen, Yueh Sheng, Yueh-Sheng Chen, Lee, Erica M., Wu, Meng Che, Meng-tse Gabriel Lee, Hsu, Wan Ting, Erica M. Lee, Po-Yang Tsou, Chien-Chang Lee, Chen, Shyr, Lee, Chien Chang, Tsou, Po Yang, Wan-Ting Hsu   +17 more
core   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

The interaction and pharmacological modulation of the cardiorespiratory responses to primary thoracic blast injury, haemorrhage resuscitation [PDF]

, 2002
Blast injuries represent a problem for civilian and military populations. The response to thoracic blast injury involves a reflex bradycardia, hypotension and apnoea.
Sawdon, Mariana Annette, Sawdon, Marina Annette, Sawdon, Marina   +2 more
core