Results 101 to 110 of about 49,127 (236)

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

Pemafibrate Improves Cholestatic Markers Regardless of the Presence of Primary Biliary Cholangitis

Hepatology Research, EarlyView.
Pemafibrate improves liver function markers related to bile flow in primary biliary cholangitis (PBC), but whether this effect is disease‐specific remains unclear. In this study, pemafibrate reduced these markers in patients with and without PBC, suggesting broader effects on bile flow beyond PBC.
Ryohei Tanigawa, Yoshiyuki Ueno, Hirokazu Takahashi, Ayumi Saito, Hideki Suganami, Atsushi Tanaka   +5 more
wiley   +1 more source

Association Between Locomotive Syndrome and Metabolic Dysfunction‐Associated Steatotic Liver Disease in a Health Examination Cohort: A Cross‐Sectional Study

Hepatology Research, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) is associated with liver fat and other health problems. In this study of 7776 adults who underwent health examinations, early mobility impairment was more common in individuals with MASLD.
Shinya Yokoyama, Takanori Ito, Taku Tanaka, Hiroaki Hiraiwa, Takashi Honda, Yoji Ishizu, Norihiro Imai, Kenta Yamamoto, Kazuki Sahara, Tetsuhito Kojima, Naoyoshi Kariya, Hiroki Kawashima   +11 more
wiley   +1 more source

A cross‐sectional analysis of cardiometabolic and lifestyle‐related profiles in men living with HIV in Japan using linked nationwide claims and health checkup data

HIV Medicine, EarlyView.
Abstract Objectives To compare objectively measured cardiometabolic health between people living with HIV (PLWH) and individuals without HIV using nationwide health checkup data linked to administrative claims, thereby partially mitigating surveillance bias associated with routine HIV care.
Kohei Yamashita, Kazuhiko Ikeuchi, Ryoko Sekiya, Yuki Arisato, Shinya Matsumoto, Toshiyuki Kishida, Akira Kado, Kazuya Okushin, Hiroshi Yotsuyanagi, Takeya Tsutsumi   +9 more
wiley   +1 more source

A healthcare cognitive decision support system for doctor–patient co‐decisions in primary care using sentiment analysis

International Transactions in Operational Research, EarlyView.
Abstract Decision support systems (DSS) in the artificial intelligence era require the integration of cognitive and affective information to support human‐centred decision‐making. This study proposes a healthcare cognitive decision support system (HC‐DSS) based on lexicon sentiment analysis for doctor–patient co‐decisions in primary care.
J.M. Moreno‐Jiménez, R. Aznar, C. Moreno‐Loscertales, M. Sancho, A. Sarango, A. Turón, J. Navarro   +6 more
wiley   +1 more source

European S2k guidelines for hidradenitis suppurativa/acne inversa Part 1. Epidemiology, diagnosis and clinical assessment

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Updated S2k hidradenitis suppurativa (HS) guidelines provide expert consensus on diagnosis, assessment and comorbidities. Expanded substantially since the 2015 version, they reflect rapid growth in HS literature and aim to improve generalist‐level patient care through evidence‐informed, consensus‐based guidance.
G. B. E. Jemec, B. Villumsen, K. R. van Straalen, H. H. van der Zee, S. Valiukevičienė, T. Tzellos, J. C. Szepietowski, A. Szegedi, D. M. L. Saunte, M. Romanelli, H. Raynal, F. Prignano, E. P. Prens, M. Podda, A. Nassif, A. Molina‐Leyva, Ł. Matusiak, A. V. Marzano, B. M. McGrath, A. I. Liakou, B. Kirby, L. Kemény, E. Just, D. Ioannidis, J. R. Ingram, R. E. Hunger, B. Horváth, P. Guillem, Ø. Grimstad, E. J. Giamarellos‐Bourboulis, M. Dolenc‐Voljč, V. Del Marmol, Z. Bukvić Mokos, V. Bettoli, F. Benhadou, F. G. Bechara, C. C. Zouboulis   +36 more
wiley   +1 more source

European Consortium for Lipodystrophies consensus definition and classification framework for monogenic lipodystrophy

Journal of Internal Medicine, EarlyView.
Abstract Lipodystrophy comprises a heterogeneous group of disorders characterized by reduced adipose tissue often associated with severe metabolic complications. Lipodystrophy may be genetic, acquired, or secondary to medical therapies initiated for other conditions.
Robert K. Semple, Martin Wabitsch, Baris Akinci, Saif Alyaarubi, Marjoleine F. Broekema, Rebecca J. Brown, Giovanni Ceccarini, Carolina Cecchetti, Solaf M. Elsayed, Antía Fernández‐Pombo, Alessandra Gambineri, Ingrid M. Jazet, Lotte Kleinendorst, Konstanze Miehle, Elif A. Oral, Flavia Prodam, Ferruccio Santini, David B. Savage, Nadia Shaukat Ali, Ekaterina Sorkina, Magdalena Szopa, Marie‐Christine Vantyghem, Camille Vatier, Corinne Vigouroux, Julia von Schnurbein, David Araújo‐Vilar   +25 more
wiley   +1 more source

GLP‐1 receptor agonists and serious adverse events: Evidence, uncertainty and clinical implications

Journal of Internal Medicine, EarlyView.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists provide benefits in weight reduction, glycaemic control in Type 2 diabetes, and cardiovascular and renal outcomes. Their widespread use has given rise to concerns regarding rare but potentially serious adverse events.
Peter Ueda
wiley   +1 more source

Periodontitis, Edentulism, and Risk of Metabolic Syndrome, Obesity, and Dyslipidemia: A Systematic Review With Meta‐Analyses

Journal of Periodontal Research, EarlyView.
The aim of this SR was to investigate the risk of metabolic syndrome (MetS) and its single components in individuals with or without periodontitis/edentulism. Within the limits of this SR, periodontitis was associated with one or more new MetS components and the association may be higher for severe periodontitis.
Luigi Barbato, Maria Di Martino, Walter Castelluzzo, Cosimo Rupe, Folco Spoleti, Michele Nieri, Francesco Cairo   +6 more
wiley   +1 more source

The Effect of Lipemia on Insulin and Adiponectin Measurement in Equine Blood Samples

Veterinary Clinical Pathology, EarlyView.
ABSTRACT Background Lipemia is a common comorbidity in horses with obesity or equine metabolic syndrome, but the impact of lipemia on the measurement of insulin and adiponectin has not been evaluated. Objective To evaluate endogenous and exogenous lipemic interference with equine insulin and adiponectin measurements via several commercial assays ...
Kimberly L. Hallowell, Andrew W. van Eps, Jeaneen C. Kulp, Lauren V. Schnabel   +3 more
wiley   +1 more source