Results 121 to 130 of about 49,127 (236)

Safety, Tolerability and Antiviral Activity of GST‐HG131 in Chronic Hepatitis B: A Randomized, Double‐Blind Phase IIa Study

Liver International, Volume 46, Issue 11, November 2026.
ABSTRACT Background and Aims Chronic hepatitis B (CHB) remains a major global health burden. Current therapies rarely achieve a functional cure due to low rates of HBsAg clearance, the persistence of the viral replication template—covalently closed circular DNA (cccDNA)—and the need for lifelong treatment.
Yuming Guo, Zhe Xu, Yuanyuan Li, John Mao, Tianxiang Zhang, Yonggang Li, Fanping Meng, Junliang Fu, Dong Ji, Yingjie Ji, Yongqian Cheng, Min Zhang, Xin Zhang, Ying Sun, Zuxiong Huang, Dachuan Cai, Wenqiang Wu, Wenhao Yan, Xiuping Yan, Guoping Li, Jinlin Hou, George Zhang, Fu‐Sheng Wang   +22 more
wiley   +1 more source

Genetic Risk and High Burden of Depression and Suicide in the Maya‐Mestizo Population of Yucatán, México

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 7, Page 431-440, October 2026.
ABSTRACT Major depression and suicide are critical public health concerns, particularly in underrepresented populations with unique genetic and sociocultural contexts. The Maya‐mestizo population presents the highest suicide rates in the country but remains understudied in psychiatric genetics. This study evaluated the association between three genetic
Marta Menjivar, Erandi Bravo, Margarita Rivera‐Balancan, Barbara Itzel Pena Espinoza   +3 more
wiley   +1 more source

A rare case of familial chylomicronemia in infancy due to homozygous LMF1 variant. [PDF]

JCEM Case Rep
Kumar PR, Dash B, Dash DK, Patro D, Sahu PK, Biswas A.   +5 more
europepmc   +1 more source

Cholestatic Liver Failure and Hypoglycemia in a Newborn: A Mitochondrial Pathology due to Citrin Deficiency

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT In an infant with cholestasis and recurrent hypoglycemia, the combination of hypercitrullinemia, hypermethioninemia, and hyperthreoninemia should prompt testing for citrin deficiency, because early metabolic and genetic diagnosis allows targeted nutritional treatment and rapid clinical improvement.
Julien Neveu, Mathilde Butori, Anne Spraul, Charlotte Hinault‐Boyer, Mourad Naïmi   +4 more
wiley   +1 more source

Life-Threatening Hypertriglyceridemia in Diabetic Ketoacidosis Successfully Managed With Therapeutic Plasma Exchange: A Case Report and Review of Literature. [PDF]

Cureus
Hossain Z, Ahmed A, Moushumi M, Salim M, Islam QT.   +4 more
europepmc   +1 more source

Severe Plasmodium vivax Malaria Complicated by Secondary Hemophagocytic Lymphohistiocytosis, Disseminated Intravascular Coagulation, and Acute Pancreatitis: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Plasmodium vivax (P. vivax) malaria, once regarded as a comparatively benign infection, is increasingly recognized as a cause of severe, potentially life‐threatening multisystem disease. Concurrent secondary hemophagocytic lymphohistiocytosis (HLH), disseminated intravascular coagulation (DIC), and acute pancreatitis complicating P.
Tasnim Nafian, Md. Abul Kalam Azad, Khaled Mahbub Murshed, Kazi Ali Aftab, Rubayet Shahriar, Abdullah Al Faisal   +5 more
wiley   +1 more source

Critical Care-Based Decision-Making and Timing of Pregnancy Termination in Hypertriglyceridemia-Induced Acute Pancreatitis Complicated by Diabetic Ketoacidosis and Intrauterine Fetal Demise: A Case Report. [PDF]

Case Rep Crit Care
Hu Y, Mao Y, Gao H.
europepmc   +1 more source

Dorsal Pancreatic Agenesis Associated With New‐Onset Diabetes Mellitus and Acute Pancreatitis in an 18‐Year‐Old Man: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Dorsal pancreatic agenesis (DPA) is a rare congenital disorder resulting from failure of development of the dorsal pancreatic bud. Complete DPA implies absence of the pancreatic neck, body, and tail and can be associated with both diabetes mellitus and pancreatitis. The patient was an 18‐year‐old man admitted with a history of epigastric pain,
Mugheesa Rab, Muhammad Hassaan Javaid, Rabia Narmeen Numani, Fozia Khanam, Muddassir Khalid, Fred Segawa   +5 more
wiley   +1 more source

Relationship of ABO blood groups with metabolic syndrome and its metabolic abnormalities in a population in North Lahore. [PDF]

Pak J Med Sci
Iqbal MP, Ahmad HS, Iqbal SP, Khurram M.
europepmc   +1 more source

A case report of young-onset type 2 diabetes patient with severe metabolic dysregulation carrying an <i>LRP6</i> variant. [PDF]

Front Endocrinol (Lausanne)
Xiang D, Yuan L, Liao S, Wang Y.
europepmc   +1 more source