Results 141 to 150 of about 49,127 (236)

Severe Hypertriglyceridemia With Lipemia-Induced Analytical Interference: Diagnostic Challenges in a Chylomicronemia Phenotype. [PDF]

JACC Case Rep
Kaur A, Bali R, Batta A, Mohan B, Chaudhary S.   +4 more
europepmc   +1 more source

Perioperative Camrelizumab and Apatinib for High‐Risk Resectable Hepatocellular Carcinoma: A Phase II Study

MedComm, Volume 7, Issue 10, October 2026.
In this study, perioperative camrelizumab plus apatinib demonstrated promising efficacy and safety in resectable hepatocellular carcinoma (HCC) patients at high risk of recurrence, achieving a major pathological response of 46.2%. The median disease‐free survival and progression‐free survival were 24.1 months and 18.3 months, respectively.
Yunlong Cui, Xu Bao, Ge Yu, Feng Fang, Qiang Li, Han Mu, Chen Liu, Qiang Wu, Wei Zhang, Huikai Li, Ping Chen, Xiaomeng Liu, Hongyuan Zhou, Tianqiang Song   +13 more
wiley   +1 more source

Hypertriglyceridemia: Causes, Consequences, Diagnosis, and Management

MedComm, Volume 7, Issue 10, October 2026.
Hypertriglyceridemia (HTG) arises from the interplay between genetic susceptibility and secondary or precipitating factors, leading to dysregulated triglyceride‐rich lipoprotein (TRL) metabolism. Increased TRL production and impaired clearance promote distinct risk phenotypes: accumulation of apolipoprotein B(apoB)‐containing TRL remnants contributes ...
Shanshan Qi, Weiwei Chen, Kunhao Chen, Song Yang, Sibo Wang, Tongtian Ni, Dan Xu, Enqiang Mao, Erzhen Chen, Ying Chen   +9 more
wiley   +1 more source

Heterozygosity for pathogenic variants in familial chylomicronemia syndrome genes: from carrier state to complex trait. [PDF]

Curr Opin Lipidol
Hegele RA.
europepmc   +1 more source

Integrative Multiomics Profiling Reveals Immune Determinants of Response to Disitamab Vedotin Plus Penpulimab in HER2‐Low Breast Cancer

MedComm, Volume 7, Issue 10, October 2026.
This prospective single‐arm study evaluated neoadjuvant disitamab vedotin plus penpulimab in 20 patients with Stage II–III HER2‐low breast cancer. The regimen showed preliminary activity (pCR 20.0% intention‐to‐treat, 25.0% evaluable; ORR 56.3%) with manageable toxicity.
Xiaoxiao Liu, Yuting Song, Lei Liu, Aaron Qi Zhang, Xin Xie, Bing Wei, Ping He, Chunying Zhuang, Juanjuan Li, Xi Yan, Tinglun Tian, Xiaorong Zhong, Jie Chen, Yan Cheng, Dan Zheng, Shibao Li, Hao Wang, Ting Luo   +17 more
wiley   +1 more source

Efficacy and Safety of Fruquintinib Plus TAS‐102 in Patients With Previously Treated Metastatic Colorectal Cancer: Results From a Single‐Arm, Multi‐Center, Phase II Study

MedComm, Volume 7, Issue 10, October 2026.
This study is the first prospective clinical trial that evaluated the efficacy and safety of fruquintinib combined with TAS‐102 in the later‐line treatment of patients with mCRC. Fruquintinib plus TAS‐102 demonstrated promising efficacy and manageable safety profile in patients with mCRC who had failed at least two standard therapies, supporting its ...
Jianjun Peng, Yong Li, Ling Huang, Jianhua Liu, Jianjun Xiao, Derong Xie, Wei Wang, Zongcheng Zhang, Chengyin Weng, Xiaoshu Chai, Huifen Li, Xiaomei Jiang, Yan Qian, Risheng Zhao, Sile Chen, Zhimin Jiang, Lingdan Le, Xueqin Li, Jianting Long, Haibo Zhang, Chuangqi Chen, Shirong Cai   +21 more
wiley   +1 more source

Associations between pyrethroid insecticide concentrations and dyslipidemia: Findings from the Dongfeng-Tongji cohort. [PDF]

Sci Adv
Yin Z, Guo Y, You Y, Guan X, Zhong G, Jia C, Wang W, Jiang Q, Wen Y, Li W, Yin Y, Zhao H, Chen S, Wang X, Jing T, Guo H, Yuan Y, He M, Wu T, Long P.   +19 more
europepmc   +1 more source

Weight Loss Improves Predicted 10‐Year MACE and Type 2 Diabetes Risk, but Benefits Partially Rebound at 1 Year

Obesity, Volume 34, Issue 10, Page 1869-1879, October 2026.
ABSTRACT Objective This study aimed to quantify changes in predicted 10‐year risk for major adverse cardiovascular events (MACE) and type 2 diabetes (T2D) across weight loss, post–weight loss (Post‐WL), and 1‐year follow‐up and to determine whether trajectories varied by exercise modality.
Abdelrahman M. Elshakankiry, Gary R. Hunter, Cátia Martins, Gordon Fisher, W. Timothy Garvey, Carrie R. Howell   +5 more
wiley   +1 more source

Influence of patient factors on target plasma volume treated attainment rate during double filtration plasmapheresis in patients with hypertriglyceridemic acute pancreatitis

Therapeutic Apheresis and Dialysis, Volume 30, Issue 5, Page 690-697, October 2026.
Abstract Introduction This study aims to investigate patient factors affecting the rate of plasma volume target attained in hypertriglyceridemic pancreatitis (HTG‐AP) patients undergoing double filtration plasmapheresis (DFPP). Methods A retrospective analysis of 82 HTG‐AP‐interpreted patients from January 2019 to April 2024 compared target plasma ...
Hui Zhang, Chenqiang Zhu, Yunlong Wu
wiley   +1 more source

Serum Folate in Relation to Lipid Abnormalities in Community-Dwelling Adults: A Population-Based Cross-Sectional Study in Zhejiang Province, China. [PDF]

Nutrients
Chen X, Lin J, Chen L, Yao W, Zhong J, Liang M.   +5 more
europepmc   +1 more source