Results 111 to 120 of about 68,532 (268)

GREM1 deficiency induced bone marrow adipose niche promotes B‐cell acute lymphoblastic leukemia disease progression

International Journal of Cancer, Volume 157, Issue 3, Page 559-572, 1 August 2025.
What's new? Too often, children treated for B‐cell acute lymphocytic leukemia (B‐ALL) experience relapse. Here, the authors investigate the role of dyslipidemia in leukemia progression. Higher adipogenicity in bone marrow mesenchymal stem cells, and increased triglyceride accumulation, are associated with higher risk of death.
Lili Song, Rui Zhang, Liya Pan, Qiang Mi, Yi Yang, Xiang Wang, Yani Ma, Shuhong Shen, Benshang Li, Yanxin Li, Li Hong   +10 more
wiley   +1 more source

Abnormal Lipoprotein Lipase in Familial Exogenous Hypertriglyceridemia [PDF]

, 1973
Paul H. Schreibman, Daniel L. Arons, Christopher D. Saudek, Ronald A. Arky   +3 more
openalex   +1 more source

Essential fatty acid deficiency, olive oil‐based intravenous lipid emulsion, and genetic polymorphisms: A pediatric randomized controlled trial

Journal of Pediatric Gastroenterology and Nutrition, Volume 81, Issue 2, Page 314-323, August 2025.
Abstract Objectives There is a concern that decreasing soybean oil (SO) content in intravenous lipid emulsions (ILEs) may increase the risk for essential fatty acid deficiency (EFAD). This study evaluates the risk of EFAD in pediatric patients who were expected to require parenteral nutrition for at least 7 days with an 80% olive oil/20% SO ILE (OO/SO ...
Cynthia Blanco, Weili Chang, Abhay J. Bhatt, Erick Gerday, Ajay J. Talati, Narendra Dereddy, Rachana Singh, Erika Ryan, Thibault Senterre   +8 more
wiley   +1 more source

Carbohydrate‐Rich Fraction of Aloe vera (L.) Burm.f. Extract Mitigates Bone Loss and Improves Metabolic Disturbance in Estrogen‐Deficient Rats

Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
Unveiling Aloe vera's potential: A nutraceutical candidate to mitigate osteoporosis and metabolic aberrations linked to Estrogen deficiency. ABSTRACT Aloe vera (L.) Burm.f., (AE) herb has been shown to have osteogenic, anti‐diabetic, and prebiotic activities in animal and human studies. Postmenopausal women generally exhibit massive bone loss, impaired
Panan Suntornsaratoon, Wajathip Bulanawichit, Wikanda Chimlek, Wanwipa Saeten, Waraporn Sorndech, Wiriyaporn Sumsakul, Suchinda Malaivijitnond, Vitoon Saengsirisuwan, Nateetip Krishnamra, Narattaphol Charoenphandhu   +9 more
wiley   +1 more source

FAMILIAL HYPERTRIGLYCERIDEMIA IN CHILDREN: DIETARY THERAPY [PDF]

, 1977
Charles J. Glueck, Margot J. Mellies, R C Tsang, P M Steiner   +3 more
openalex   +1 more source

Differences in mRNA Expression of Selected Cytochrome P450, Transporters and Nuclear Receptors Among Various Rat Models of Metabolic Syndrome

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 2, August 2025.
Metabolic syndrome (MetS) is a combination of several factors, which lead to a higher risk of cardiovascular and other diseases. To study MetS, its mechanisms and means to alleviate complications associated with it, there is a demand for suitable animal models and their strains.
Jan Soukop, Zuzana Rácová, Ludmila Kazdová, Iveta Zapletalová, Martin Poruba, Hana Malínská, Martina Hüttl, Irena Marková, Kristýna Nováková, Rostislav Večeřa   +9 more
wiley   +1 more source

Sex Differences in Severity and Risk Factors for Ischemic Stroke in Patients With Hyperlipidemia

Neuroscience Insights
Objective: This study aims to determine sex differences in poststroke hypertriglyceridemia (serum triglyceride levels ⩾ 200 mg/dl) and high stroke severity in ischemic stroke patients.
Emmanuel Imeh-Nathaniel, Samuel Imeh-Nathaniel, Adebobola Imeh-Nathaniel, Oreoluwa Coker-Ayo, Nikhil Kulkarni, Thomas I Nathaniel   +5 more
doaj   +1 more source

A biochemical and morphologic study of very low density lipoproteins in carbohydrate-induced hypertriglyceridemia [PDF]

, 1971
Neil B. Ruderman, Albert L. Jones, Ronald M. Krauss, Eleazar Shafrir   +3 more
openalex   +1 more source

Role for the liver X receptor agonist 22‐ketositosterol in preventing disease progression in an Alzheimer's disease mouse model

British Journal of Pharmacology, Volume 182, Issue 16, Page 3744-3766, August 2025.
Background and Purpose Liver X receptors (LXRs) are promising therapeutic targets for alleviating Alzheimer's disease (AD) symptoms. We assessed the impact of the semi‐synthetic LXR agonist 22‐ketositosterol on disease progression in an AD mouse model.
Nikita Martens, Na Zhan, Sammie C. Yam, Marcella Palumbo, Lorenzo Pontini, Frank P. J. Leijten, Leonie van Vark‐van der Zee, Gardi Voortman, Silvia Friedrichs, Albert Gerding, Maura Marinozzi, Johan W. Jonker, Folkert Kuipers, Dieter Lütjohann, Tim Vanmierlo, Monique T. Mulder   +15 more
wiley   +1 more source

Association of Triglyceride–Glucose Body Mass Index with Target Organ Damage in Essential Hypertension: A Retrospective Cohort Study

The Journal of Clinical Hypertension, Volume 27, Issue 8, August 2025.
ABSTRACT The triglyceride–glucose body mass index (TyG‐BMI) is an emerging composite metabolic indicator in cardiovascular research. However, the link between TyG‐BMI and target organ damage (TOD) in essential hypertension (EH) remains uncertain. This study investigated the association between TyG‐BMI and TOD in patients with EH.
Xiaodong Huang, Junnan Ye, Siyao Liu, Zhihong Xu, Mandong Pan, Jiyan Lin, Liangdi Xie   +6 more
wiley   +1 more source