Results 111 to 120 of about 103,321 (345)

An Open‐Label, Multicenter, Phase II Study of Bexarotene in Patients with Adult T‐Cell Leukemia/Lymphoma

The Journal of Dermatology, EarlyView.
ABSTRACT A multicenter, open‐label, historically controlled, 2‐arm phase II study was conducted to evaluate the safety, efficacy, and pharmacokinetics of bexarotene in Japanese patients with adult T‐cell lymphoma/leukemia (ATL). The study enrolled patients with indolent ATL and skin lesions and patients with aggressive ATL who had skin relapse after ...
Kentaro Yonekura, Ikko Muto, Motoi Takenaka, Jun Aoi, Taku Fujimura, Masahiro Amano, Takuro Kanekura, Takuya Miyagi, Kanami Saito, Eiji Kiyohara, Takatoshi Shimauchi, Ken Watanabe, Tomoko Miyake, Takamichi Ito, Hisashi Uhara, Kazuyasu Fujii, Akihito Sudo, Toshiki Watanabe, Keiji Iwatsuki   +18 more
wiley   +1 more source

ApoE gene therapy: an overview and update [PDF]

, 2005
Atherosclerosis remains the leading cause of death in industrialized societies. Apolipoprotein E (ApoE) is an attractive candidate to treat hypercholesterolemia and coronary heart disease, as it is a circulating protein with pleiotropic ...
Owen, J.S.
core  

Vitamin D3 supplementation of a high fat high sugar diet ameliorates prediabetic phenotype in female LDLR–/–and LDLR+/+mice [PDF]

, 2017
© 2017 The Authors. Immunity, Inflammation and Disease Published by John Wiley & Sons Ltd. INTRODUCTION: Fatty liver disease is prevalent in populations with high caloric intake.
Asai, Baldock, Bieghs, Bora, Cani, Chan, Chawla, Del Ben, DeLuca, Dongiovanni, Drewnowski, George, Giugliano, Glaros, Hummasti, Iwaki, Jorde, Jump, Kalra, Karbowska, Kennedy, Kheder, Kitson, Kleiner, Kraakman, Lira, Livak, Lytle, Machado, Madar, Marcotorchino, Merat, Minto, Oh, Okamoto, Parekh, Pham, Roth, Saraswathi, Schwen, Sergeev, Shu, Subramanian, Teramoto, Tintut, Vanlint, Wortsman, Wouters, Yin, Zhang, Zhang   +50 more
core   +1 more source

Women's and Health Care Professionals' Experiences of Discontinuing Hormone Replacement Therapy (HRT): A Systematic Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Hormone Replacement Therapy (HRT) is used to manage menopausal symptoms, particularly vasomotor symptoms (VMS). HRT prescribing rates are rising, but most women will eventually discontinue. Objectives To explore the experiences of women stopping HRT, why women restart HRT, and the HCPs advising them. Search Strategy Embase, MEDLINE,
Sarah Bunnewell, Sabrina Keating, Jo Parsons, Martha Hickey, Sarah Hillman   +4 more
wiley   +1 more source

Association between one-hour post-load plasma glucose levels and vascular stiffness in essential hypertension [PDF]

, 2012
Objectives: Pulse wave velocity (PWV) is a surrogate end-point for cardiovascular morbidity and mortality. A plasma glucose value $155 mg/dl for the 1-hour post-load plasma glucose during an oral glucose tolerance test (OGTT) is able to identify ...
Arturi, F, Carullo, G, Grillo, N, Maio, R, Miceli, S, Pascale, A, Perticone, F., Sciacqua, A, Sesti, G   +8 more
core   +2 more sources

The Incidence of Propofol-Induced Hypertriglyceridemia and Identification of Associated Risk Factors

Critical Care Explorations, 2020
Supplemental Digital Content is available in the text. Objectives: The objective of this study was to describe the incidence of propofol-induced hypertriglyceridemia and the risk factors associated with hypertriglyceridemia in mechanically ventilated ICU
Michael J Corrado, Mary P. Kovacevic, Kevin M. Dube, Kenneth E. Lupi, P. Szumita, Jeremy R. DeGrado   +5 more
semanticscholar   +1 more source

Influence of patient factors on target plasma volume treated attainment rate during double filtration plasmapheresis in patients with hypertriglyceridemic acute pancreatitis

Therapeutic Apheresis and Dialysis, EarlyView.
Abstract Introduction This study aims to investigate patient factors affecting the rate of plasma volume target attained in hypertriglyceridemic pancreatitis (HTG‐AP) patients undergoing double filtration plasmapheresis (DFPP). Methods A retrospective analysis of 82 HTG‐AP‐interpreted patients from January 2019 to April 2024 compared target plasma ...
Hui Zhang, Chenqiang Zhu, Yunlong Wu
wiley   +1 more source

Effect of Statins and PCSK9 Inhibition on Metabolic Dysfunction–Associated Steatotic Liver Disease

Journal of Digestive Diseases, EarlyView.
Statins reduce low‐density lipoprotein‐cholesterol (LDL‐C) production and reduce cardiovascular risk and hepatic steatosis in metabolic dysfunction‐associated steatotic liver disease (MASLD), but they have no significant effect on steatohepatitis and/or fibrosis.
Eleni Theocharidou, Thomas Gossios
wiley   +1 more source

Immunovirological outcomes and resistance patterns at 4 years of antiretroviral therapy use in HIV-infected patients in Cambodia [PDF]

, 2011
Objectives  To report immunovirological outcomes and resistance patterns in adults treated with triple combination antiretroviral therapy (cART) for 4 years in an HIV programme of Phnom Penh, Cambodia.
Balkan, Suna, Chanchhaya, Ngeth, Ferradini, Laurent, Narom, Prak, Nerrienet, Eric, Pujades-Rodríguez, Mar, Schramm, Birgit, Som, Leakena   +7 more
core   +2 more sources

Advances and Future Perspectives for the Management of Non‐Small Cell Lung Cancer in Australia: A Narrative Review

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Lung cancer remains Australia's leading cause of cancer death. With new screening and evolving therapies, equitable access and workforce readiness are essential. This review discusses current and emerging treatments for NSCLC in Australia, clinical trials underway, and future directions in delivering optimal, accessible care nationwide.
Lauren Julia Brown, Graham Meredith, Bo Gao, Pei Ding, Harriet Gee, Inês Pires da Silva, Adnan Nagrial, Eric Hau   +7 more
wiley   +1 more source