Results 111 to 120 of about 78,803 (280)

Correlation between serum SUMO1 level and hypertriglyceridemia in type 2 diabetes mellitus patients

Shanghai Jiaotong Daxue xuebao. Yixue ban
Objective·To explore the correlation between serum small ubiquitin-like modifier 1 (SUMO1) levels and hypertriglyceridemia in patients with type 2 diabetes mellitus (T2DM).Methods·A total of 239 newly diagnosed T2DM patients were recruited from the ...
ZHANG Xinyan, LI Han, RAN Hui, SU Qing, ZHANG Hongmei   +4 more
doaj   +1 more source

Advances and Future Perspectives for the Management of Non‐Small Cell Lung Cancer in Australia: A Narrative Review

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Lung cancer remains Australia's leading cause of cancer death. With new screening and evolving therapies, equitable access and workforce readiness are essential. This review discusses current and emerging treatments for NSCLC in Australia, clinical trials underway, and future directions in delivering optimal, accessible care nationwide.
Lauren Julia Brown, Graham Meredith, Bo Gao, Pei Ding, Harriet Gee, Inês Pires da Silva, Adnan Nagrial, Eric Hau   +7 more
wiley   +1 more source

Prevalence and Patterns of Dyslipidemia in West District of Delhi: Prospective Study for Lifestyle Modification to Prevent Heart Disease [PDF]

Indian Journal of Medical Biochemistry
Introduction: Dyslipidemia involves abnormal blood lipid levels, such as high cholesterol, high triglycerides, high low-density lipoprotein (LDL), and low high-density lipoprotein (HDL).
Vineet Banga, K Gloria T Ro
doaj   +1 more source

Fenofibrate potentiates the therapeutic efficacy of EZH2 inhibitors on melanoma via TRIM21‐ and OTUD4‐mediated EZH2 ubiquitination

British Journal of Pharmacology, EarlyView.
Background and Purpose EZH2 (enhancer of zeste homologue 2) inhibitors are an emerging class of drugs that target epigenetic regulation. However, their efficacy in solid tumours has been limited, partly due to drug‐induced upregulation of fatty acid synthesis.
Rui Cheng, Yuanjun Tang, Xuedi Cao, Xiaotong Yu, Zhanya Huang, Yunyun Guo, Renjing Jin, Yan Wang, Yang Liu, Lixiang Xue, Yuqing Wang   +10 more
wiley   +1 more source

Early‐Onset Digestive System Cancers: Risk Factors and Clinicopathological and Molecular Features Across Organ Sites

Cancer Science, EarlyView.
Shared risk factors, clinical features, and tumor characteristics across multiple early‐onset cancer types are shown in this Graphical Abstract. Integrative approaches combining molecular pathology, oncology, and population sciences offer opportunities to clarify underlying mechanisms and help us develop preventive strategies for early‐onset cancers ...
Nobuhiro Nakazawa, Satoko Ugai, Atsushi Kondo, Kosuke Matsuda, Shu Kato, Genki Usui, Shiori Tanaka, Hwa‐Young Lee, Xinyuan Zhang, Hideo Miyagawa, Mai Chan Lau, Hiroshi Saeki, Yukihide Kanemitsu, Andrew T. Chan, Shuji Ogino, Minkyo Song, Juha P. Väyrynen, Tomotaka Ugai   +17 more
wiley   +1 more source

Steatotic Liver Disease: A Key Related Risk Factor in the Emergence of Metabolic Syndrome‐Related Disorders

Hepatology Research, EarlyView.
It is speculated that the onset of obesity‐related diseases follows the sequence of obesity → SLD → MetS‐related diseases. In this study, the contribution of SLD to each MetS‐related disease was large for T2D and hypertension and SLD contributed to the onset and new onset of the disease by the 7‐year follow‐up.
Yoshihiro Kamada, Makoto Fujii, Hitoshi Nishizawa, Shiro Fukuda, Makoto Yamada, Iichiro Shimomura, Eiji Miyoshi   +6 more
wiley   +1 more source

Risk of end‐stage renal disease in Korean patients with type 2 diabetes according to cumulative low‐density lipoprotein cholesterol levels

Journal of Diabetes Investigation, EarlyView.
High cumulative LDL‐C levels increase ESRD risk in type 2 diabetes, particularly among patients using insulin, those receiving multiple antidiabetic medications, and those with longer diabetes duration. Longer exposure to elevated LDL‐C further increases risk, underscoring the need for intensive LDL‐C control.
Da‐Yeon Lee, Kyung‐Do Han, Ji‐Hee Ko, Han‐Na Jang, Sun Joon Moon, Hye‐Mi Kwon, Se‐Eun Park, Won‐Young Lee, Eun‐Jung Rhee   +8 more
wiley   +1 more source

Triglycerides and T Cells in Cardiovascular Risk

JACC: Basic to Translational Science
Summary: Triglycerides and T cells play a key role in atherosclerosis, the leading cause of cardiovascular disease (CVD). Moderately elevated triglycerides have emerged as a causal risk factor, and T cells are a prominent component of atherosclerotic ...
Nathalie A. Reilly, PhD, Janneke W.C.M. Mulder, MD, Koen F. Dekkers, PhD, Thomas B. Kuipers, BSc, Leonie C. van Vark-van der Zee, BSc, Monique T. Mulder, PhD, Jeanine E. Roeters van Lennep, MD, PhD, J. Wouter Jukema, MD, PhD, Bastiaan T. Heijmans, PhD   +8 more
doaj   +1 more source

Association of Adverse Childhood Experiences and Metabolic Syndrome: A Systematic Review and Meta‐Analysis

Obesity Reviews, EarlyView.
ABSTRACT Background The association between adverse childhood experiences (ACEs) and metabolic syndrome (MetS) across life course and its components (abdominal obesity, elevated blood pressure, dyslipidemia, and hyperglycemia) is poorly understood. Methods Three databases were screened for studies published January 2000–February 2024 that examined the ...
Joohan Kim, Luyu Xie, Alejandra Fernandez, Jaime P. Almandoz, Sarah E. Messiah   +4 more
wiley   +1 more source

[Hypertriglyceridemias].

Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 1999
Triglyceride atherogenicity is still a matter of controversy for reasons related to their biological and epidemiological characteristics. The authors discuss and review several of these problems, as well as the metabolic relationship of triglycerides and HDL-cholesterol, data indicating a strong influence of triglycerides on cardiovascular risk ...
J M, Silva, M M, Méndez, N, Devesa
openaire   +1 more source