Journal of Diabetes Investigation, Volume 16, Issue 8, Page 1473-1486, August 2025.Diabetic nephropathy (DN) is a major complication of diabetes, leading to end‐stage renal disease. This study identified 109 differentially expressed genes (DEGs) and validated LOX as a novel diagnostic biomarker through integrated bioinformatics and experimental analysis.
Shahad W. Kattan +11 more
wiley +1 more source
Gene Expression Shifts in Emperor Penguin Adaptation to the Extreme Antarctic Environment
Molecular Ecology, Volume 34, Issue 15, August 2025.ABSTRACT Gene expression can accelerate ecological divergence by rapidly tweaking the response of an organism to novel environments, with more divergent environments exerting stronger selection and supposedly, requiring faster adaptive responses. Organisms adapted to extreme environments provide ideal systems to test this hypothesis, particularly when ...
Josephine R. Paris +11 more
wiley +1 more source
Therapeutic Advances in HematologyPolyethylene-glycolated Escherichia coli -derived l -asparaginase (pegaspargase, pASP) is an essential component of paediatric-inspired regimens for the treatment of acute lymphoblastic leukaemia/lymphoma; nonetheless, is characterised by severe and ...
Gaia Ciolli +10 more
doaj +1 more source
The FASEB Journal, Volume 39, Issue 13, 15 July 2025.Female and male mice were fed manganese (Mn)‐depleted or Mn‐enriched diets in combination with either a low fat‐low sucrose (LFLS) or high fat‐high sucrose (HFHS) diet for 28 days. A sex‐specific metabolic response was observed under Mn‐depleted conditions, particularly affecting monoacylglycerol levels.
Fredy Alexander Guevara Agudelo +8 more
wiley +1 more source
Abnormal bile acid absorption in familial hypertriglyceridemia
Journal of Lipid Research, 1995 To better define the abnormality of bile acid metabolism associated with hypertriglyceridemia, we measured bile acid kinetics and absorption as well as preferential use of newly synthesized cholesterol for bile acid synthesis in eleven controls and ten ...
W C Duane
doaj
Lipid composition of fat particles from normal man and patients with idiopathic hypertriglyceridemia
, 1966 Daniel Porte +2 more
openalex +1 more source
Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein E. [PDF]
, 1997 Tetsu Ebara +3 more
openalex +1 more source
Common genetic variation in the promoter of the human apo CIII gene abolishes regulation by insulin and may contribute to hypertriglyceridemia. [PDF]
, 1995 W W Li +5 more
openalex +1 more source
Characterization of a model of dietary-induced hypertriglyceridemia in young, nonobese rats.
, 1979 Gerald M. Reaven +3 more
openalex +1 more source
Vascular reactivity and effect of serum in a rat model of hypertriglyceridemia and hypertension*1 [PDF]
, 1997 Guadalupe Baños
openalex +1 more source