Results 131 to 140 of about 103,321 (345)

Integrative proteomic analysis provides novel therapeutic insights for etiological subtypes of diabetes

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Type 2 diabetes (T2D) is a highly heterogeneous disease characterised by subtypes with variations in aetiology, disease progression, and risk of complications. However, potential drug targets for these subtypes have not been explored. This study aims to investigate potential drug targets by integrating proteomics.
Jiahe Wei, Hanzhang Wu, Ningjian Wang, Jiahao Zhu, Ranjit Mohan Anjana, Aleksandr V. Sokolov, Helgi B. Schiöth, Viswanathan Mohan, Xiao Tan   +8 more
wiley   +1 more source

Factors associated with abdominal obesity and lipid alterations in low-income adults

Acta Scientiarum. Health Sciences
To evaluate the prevalence of abdominal obesity, hypercholesterolemia and hypertriglyceridemia and its associated factors in adults in a low income region.
Cristyane Nathália Gomes Mendonça, Vanessa Sá Leal, Juliana Souza Oliveira, Marcela Claudia de Paula Oliveira, Marco Aurélio de Valois Correia Júnior, Pedro Israel Cabral de Lira, Emilia Chagas Costa   +6 more
doaj   +1 more source

The association of hypertriglyceridemia with cardiovascular events and pancreatitis: a systematic review and meta-analysis

BMC Endocrine Disorders, 2012
Background Hypertriglyceridemia may be associated with important complications. The aim of this study is to estimate the magnitude of association and quality of supporting evidence linking hypertriglyceridemia to cardiovascular events and pancreatitis ...
Murad M Hassan, Hazem Ahmad, Coto-Yglesias Fernando, Dzyubak Svitlana, Gupta Shabnum, Bancos Irina, Lane Melanie A, Erwin Patricia J, Berglund Lars, Elraiyah Tarig, Montori Victor M   +10 more
doaj   +1 more source

The cardiovascular risk of young women with polycystic ovary syndrome: an observational, analytical, prospective case-control study [PDF]

, 2004
To evaluate the cardiovascular risk of polycystic ovary syndrome (PCOS), we investigated lipid profile, metabolic pattern, and echocardiography in 30 young women with PCOS and 30 healthy age- and body mass index (BMI)-matched women. PCOS women had higher
CASCELLA, TERESA, COLAO, ANNAMARIA, F. Zullo, L. Tauchmanovà, LOMBARDI, GAETANO, ORIO, FRANCESCO, PALOMBA, STEFANO, SPINELLI, LETIZIA   +7 more
core   +1 more source

Investigating multimorbidity trajectories in people living with MASLD diagnosis: A trajectory analysis using the UK Biobank

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Background Metabolic dysfunction‐associated steatotic liver disease (MASLD) is an emerging global health concern, and its presence increases the risk of multi‐system diseases. This study aimed to investigate the multimorbidity trajectories of chronic diseases in people living with MASLD.
Fang Lu, Hailin Yang, Bingyang She, Qianhui Lu, Yining Bao, Wai‐Kay Seto, William C. W. Wong, Man‐Fung Yuen, Yingli He, Xinyuan He, Fanpu Ji, Lei Zhang   +11 more
wiley   +1 more source

Tirzepatide and the 10‐year predicted risk of cardiovascular disease and type 2 diabetes in adults with obesity and prediabetes: A post hoc analysis from the three‐year SURMOUNT‐1 trial

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aim We assessed the association between tirzepatide and the 10‐year predicted risk of developing cardiovascular disease (CVD) and type 2 diabetes (T2D) among three‐year SURMOUNT‐1 trial participants. Materials and Methods This post hoc analysis applied validated risk engines that predict 10‐year CVD (atherosclerotic cardiovascular disease ...
Emily R. Hankosky, Jeremie Lebrec, Clare J. Lee, Georgios K. Dimitriadis, Irina Jouravskaya, Adam Stefanski, W. Timothy Garvey   +6 more
wiley   +1 more source

Pharmacokinetics and adverse effects of a long‐acting IM dopamine agonist: Cabergoline in healthy horses

Equine Veterinary Education, EarlyView.
Summary Background Pituitary pars intermedia dysfunction (PPID) is commonly treated with pergolide mesylate, a dopamine receptor agonist. Cabergoline is a dopamine receptor agonist that has shown activity on prolactin secretion in horses for up to 10 days.
H. Hess, A. Bracken, S. Rao, Y. Nout‐Lomas, D. Gustafson, L. Bass   +5 more
wiley   +1 more source

Identification and Validation of Hub Genes in Acute Pancreatitis and Hypertriglyceridemia

Diabetes, Metabolic Syndrome and Obesity, 2022
Shiyu Zhang, Zhihai Liang, Xuelian Xiang, Li Liu, Huiying Yang, Guodu Tang Department of Gastroenterology, The First Affiliated Hospital of Guangxi Medical University, Nanning City, Guangxi Province, People’s Republic of ChinaCorrespondence: Guodu Tang ...
Zhang S, Liang Z, Xiang X, Liu L, Yang H, Tang G   +5 more
doaj  

Waist circumference provides an indication of numerous cardiometabolic risk factors in adults with cerebral palsy [PDF]

, 2014
This article has been made available through the Brunel Open Access Publishing Fund.Objective: To report the prevalence of cardiometabolic risk factors in a cohort of adults with cerebral palsy (CP) and to investigate the ability of anthropometric ...
Crowley, VE, Gormley, J, Hensey, O, McGahey, A, Ryan, JM   +4 more
core   +1 more source

Association of Tooth Loss With Stress and Depressive Symptoms in Korean Adults: An Analysis Using Korean National Health and Nutrition Examination Survey (KNHANES VI) (2013, 2015)

Gerodontology, EarlyView.
ABSTRACT Objective To examine the association between tooth loss and depressive symptoms in the Korean population using nationally representative data. Background Tooth loss negatively impacts oral function, aesthetics, and overall quality of life. It can lead to systemic issues, such as nutritional deficiencies, and is associated with mental health ...
Jae‐hun Koh, Eun‐Jae Choi, Jung‐Ah Lee, Seon‐Jip Kim, Hyun‐Jae Cho   +4 more
wiley   +1 more source